deferoxamine has been researched along with Lung Diseases in 29 studies
Deferoxamine: Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
desferrioxamine B : An acyclic desferrioxamine that is butanedioic acid in which one of the carboxy groups undergoes formal condensation with the primary amino group of N-(5-aminopentyl)-N-hydroxyacetamide and the second carboxy group undergoes formal condensation with the hydroxyamino group of N(1)-(5-aminopentyl)-N(1)-hydroxy-N(4)-[5-(hydroxyamino)pentyl]butanediamide. It is a siderophore native to Streptomyces pilosus biosynthesised by the DesABCD enzyme cluster as a high affinity Fe(III) chelator.
Lung Diseases: Pathological processes involving any part of the LUNG.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We report a case of thalassemia major with biopsy-proven pulmonary iron overload, in which thoracic high-resolution computed tomography revealed a morphological-functional correlation consistent with small airway disease." | 1.31 | Pulmonary iron overload in thalassemia major presenting as small airway disease. ( Khong, PL; Lam, WK; Ooi, GC; Trendell-Smith, NJ; Tsang, KW, 2002) |
| "Pretreatment with deferoxamine resulted in a significant decrease in lung leak as compared to animals pretreated with vehicle prior to I/R (DES-I/R = 0." | 1.29 | Desferal attenuates TNF release following hepatic ischemia/reperfusion. ( Campbell, DA; Colletti, LM; Remick, DG, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (51.72) | 18.7374 |
| 1990's | 9 (31.03) | 18.2507 |
| 2000's | 4 (13.79) | 29.6817 |
| 2010's | 1 (3.45) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sato, K | 2 |
| Tashiro, Y | 1 |
| Chibana, S | 1 |
| Yamashita, A | 1 |
| Karakawa, T | 1 |
| Kohrogi, H | 1 |
| Noori, NM | 1 |
| Keshavarz, K | 1 |
| Shahriar, M | 1 |
| Ooi, GC | 1 |
| Khong, PL | 1 |
| Lam, WK | 1 |
| Trendell-Smith, NJ | 1 |
| Tsang, KW | 1 |
| SUNDERMANN, A | 1 |
| PANZRAM, G | 1 |
| Arimoto, T | 1 |
| Kadiiska, MB | 1 |
| Corbett, J | 1 |
| Mason, RP | 1 |
| Teixeira, KC | 1 |
| Soares, FS | 1 |
| Rocha, LG | 1 |
| Silveira, PC | 1 |
| Silva, LA | 1 |
| Valença, SS | 1 |
| Dal Pizzol, F | 1 |
| Streck, EL | 1 |
| Pinho, RA | 1 |
| Poggio, GL | 1 |
| Lucioni, F | 1 |
| Ward, PA | 4 |
| Till, GO | 3 |
| Kunkel, R | 1 |
| Beauchamp, C | 1 |
| Meulenbelt, J | 1 |
| Dormans, JA | 1 |
| van Bree, L | 1 |
| Rombout, PJ | 1 |
| Sangster, B | 1 |
| Colletti, LM | 1 |
| Remick, DG | 1 |
| Campbell, DA | 1 |
| Adamson, IY | 2 |
| Sienko, A | 1 |
| Tenenbein, M | 2 |
| Giardina, PJ | 1 |
| Grady, RW | 1 |
| Kang, SA | 1 |
| Jang, YJ | 1 |
| Park, H | 1 |
| Capaccioli, L | 1 |
| D'Ambrosio, A | 1 |
| Paciotti, F | 1 |
| Acquaviva, A | 1 |
| Morgese, G | 1 |
| Shannon, M | 1 |
| Curiel, DT | 1 |
| Agarwal, S | 1 |
| Rømer, MU | 1 |
| Wagner, E | 1 |
| Cotten, M | 1 |
| Birnstiel, ML | 1 |
| Boucher, RC | 1 |
| Kobayashi, T | 1 |
| Kubo, K | 1 |
| Ward, HE | 1 |
| Hicks, M | 1 |
| Nicholson, A | 1 |
| Berend, N | 1 |
| Boyce, NW | 1 |
| Campbell, D | 1 |
| Holdsworth, SR | 1 |
| Hatherill, JR | 1 |
| Tourtellotte, WW | 1 |
| Lutz, MJ | 1 |
| Johnson, KJ | 1 |
| Kunkel, RG | 1 |
| Wilson, BS | 1 |
| Annesley, TM | 1 |
| Etienne, JP | 1 |
| Passa, P | 1 |
| Turbina, NS | 1 |
| Stacher, A | 1 |
| Cerruti Mainardi, P | 1 |
| Massimo, L | 1 |
| Desenne, JJ | 1 |
| Layrisse, M | 1 |
| Pecora, L | 1 |
| Cascini, F | 1 |
| De Siena, F | 1 |
3 reviews available for deferoxamine and Lung Diseases
| Article | Year |
|---|---|
Chelation therapy in beta-thalassemia: the benefits and limitations of desferrioxamine.
Topics: Adolescent; Adult; Chelating Agents; Chelation Therapy; Child; Deferoxamine; Growth Disorders; Heari | 1995 |
[Use of desferal in treatment of sideroses of different origin. (Literature review)].
Topics: Anemia; Anemia, Aplastic; Anemia, Sideroblastic; Animals; Bile; Child, Preschool; Deferoxamine; Hemo | 1968 |
[Diseases caused by iron metabolism disorders and their therapy].
Topics: Adult; Anemia, Hypochromic; Anti-Glomerular Basement Membrane Disease; Bloodletting; Deferoxamine; D | 1969 |
26 other studies available for deferoxamine and Lung Diseases
| Article | Year |
|---|---|
Role of lipid-derived free radical in bleomycin-induced lung injury in mice: availability for ESR spin trap method with organic phase extraction.
Topics: Animals; Anti-Bacterial Agents; Antidotes; Bleomycin; Bronchoalveolar Lavage Fluid; Deferoxamine; Fr | 2008 |
Cardiac and pulmonary dysfunction in asymptomatic beta-thalassanemia major.
Topics: Adolescent; Asymptomatic Diseases; beta-Thalassemia; Blood Transfusion; Case-Control Studies; Child; | 2012 |
Pulmonary iron overload in thalassemia major presenting as small airway disease.
Topics: Adult; Airway Obstruction; beta-Thalassemia; Biopsy; Chelation Therapy; Combined Modality Therapy; D | 2002 |
[DISEASES OF THE LUNG].
Topics: Adrenal Cortex Hormones; Child; Deferoxamine; Diagnosis, Differential; Glomerulonephritis; Granuloma | 1964 |
Synergistic production of lung free radicals by diesel exhaust particles and endotoxin.
Topics: Allopurinol; Animals; Anti-Inflammatory Agents; Bronchoalveolar Lavage Fluid; Deferoxamine; Disease | 2005 |
Attenuation of bleomycin-induced lung injury and oxidative stress by N-acetylcysteine plus deferoxamine.
Topics: Acetylcysteine; Animals; Antineoplastic Agents; Antioxidants; Bleomycin; Catalase; Deferoxamine; Dru | 2008 |
[Study of a case of idiopathic pulmonary hemosiderosis treated with an iron chelating agent (desferoxamine B, "Desferal")].
Topics: Adolescent; Deferoxamine; Hemosiderosis; Humans; Lung Diseases; Male | 1967 |
Evidence for role of hydroxyl radical in complement and neutrophil-dependent tissue injury.
Topics: Acute Disease; Animals; Capillaries; Complement Activation; Complement C3; Complement System Protein | 1983 |
Desferrioxamine treatment reduces histological evidence of lung damage in rats after acute nitrogen dioxide (NO2) intoxication.
Topics: Administration, Inhalation; Animals; Body Weight; Deferoxamine; Female; Injections, Intravenous; Lun | 1993 |
Desferal attenuates TNF release following hepatic ischemia/reperfusion.
Topics: Alanine Transaminase; Animals; Deferoxamine; Disease Models, Animal; Liver; Liver Diseases; Lung Dis | 1994 |
Pulmonary toxicity of deferoxamine in iron-poisoned mice.
Topics: Animals; Atmosphere Exposure Chambers; Bronchoalveolar Lavage Fluid; Deferoxamine; Disease Models, A | 1993 |
In vivo dual effects of vitamin C on paraquat-induced lung damage: dependence on released metals from the damaged tissue.
Topics: Animals; Ascorbic Acid; Breath Tests; Deferoxamine; Ethane; Lipid Peroxidation; Lung; Lung Diseases; | 1998 |
[Idiopathic pulmonary hemosiderosis].
Topics: Child, Preschool; Chronic Disease; Cortisone; Deferoxamine; Female; Hemosiderosis; Humans; Immunosup | 1978 |
Desferrioxamine in acute iron poisoning.
Topics: Deferoxamine; Female; Humans; Iron; Lung Diseases | 1992 |
Desferrioxamine and pulmonary injury.
Topics: Deferoxamine; Humans; Lung Diseases | 1992 |
Gene transfer to respiratory epithelial cells via the receptor-mediated endocytosis pathway.
Topics: Animals; Cell Line; Coleoptera; Deferoxamine; DNA; Drug Interactions; Endocytosis; Epithelial Cells; | 1992 |
[Oxidant-induced lung injury].
Topics: Animals; Deferoxamine; Free Radical Scavengers; Free Radicals; Hydroxides; Lung Diseases; Oxygen; Pa | 1990 |
Deferoxamine infusion does not inhibit bleomycin-induced lung damage in the rat.
Topics: Animals; Bleomycin; Deferoxamine; Infusion Pumps; Iron; Lung; Lung Diseases; Osmolar Concentration; | 1988 |
Modulation of normobaric pulmonary oxygen toxicity by hydroxyl radical inhibition.
Topics: Animals; Capillary Permeability; Deferoxamine; Hydroxides; Hydroxyl Radical; Lung; Lung Diseases; Ma | 1987 |
Lipid peroxidation and acute lung injury after thermal trauma to skin. Evidence of a role for hydroxyl radical.
Topics: Animals; Burns; Capillary Permeability; Chelating Agents; Deferoxamine; Dimethyl Sulfoxide; Hydroxid | 1985 |
Mediation of IgA induced lung injury in the rat. Role of macrophages and reactive oxygen products.
Topics: Animals; Catalase; Deferoxamine; Dimethyl Sulfoxide; Dinitrophenols; Free Radicals; Haptens; Immune | 1986 |
Cutaneous thermal burn and oxidant-mediated acute lung injury: appearance in serum of lung-related LDH isoenzyme.
Topics: Animals; Burns; Deferoxamine; Free Radicals; Isoenzymes; L-Lactate Dehydrogenase; Lung; Lung Disease | 1985 |
[Infectious mononucleosis with pulmonary, pleural and mediastinal involvement].
Topics: Adult; Agglutination Tests; Deferoxamine; Hemochromatosis; Hepatitis A; Hepatomegaly; Humans; Infect | 1969 |
[Nosological classification and new therapeutic trends in idiopathic pulmonary hemosiderosis].
Topics: Adrenal Cortex Hormones; Azathioprine; Blood Protein Electrophoresis; Child, Preschool; Deferoxamine | 1966 |
Mobilisation of iron by desferrioxamine in cases with low serum iron.
Topics: Anemia, Hypochromic; Bone Marrow Examination; Deferoxamine; Female; Hemoglobinuria; Humans; Injectio | 1969 |
[Research on the desferrioxamine test in welders].
Topics: Adult; Deferoxamine; Humans; Iron; Lung Diseases; Middle Aged; Occupational Diseases; Siderosis; Wel | 1967 |