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deferoxamine and Low Bone Density

deferoxamine has been researched along with Low Bone Density in 16 studies

Deferoxamine: Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
desferrioxamine B : An acyclic desferrioxamine that is butanedioic acid in which one of the carboxy groups undergoes formal condensation with the primary amino group of N-(5-aminopentyl)-N-hydroxyacetamide and the second carboxy group undergoes formal condensation with the hydroxyamino group of N(1)-(5-aminopentyl)-N(1)-hydroxy-N(4)-[5-(hydroxyamino)pentyl]butanediamide. It is a siderophore native to Streptomyces pilosus biosynthesised by the DesABCD enzyme cluster as a high affinity Fe(III) chelator.

Research Excerpts

ExcerptRelevanceReference
"The bone histology in patients with chronic renal failure and aluminum-related bone disease does not always show the excess accumulation of unmineralized osteoid (matrix) characteristic of osteomalacia."7.67Osteomalacia and aplastic bone disease in aluminum-related osteodystrophy. ( Andress, DL; Coburn, JW; Endres, DB; Maloney, NA; Sherrard, DJ, 1987)
"The bone histology in patients with chronic renal failure and aluminum-related bone disease does not always show the excess accumulation of unmineralized osteoid (matrix) characteristic of osteomalacia."3.67Osteomalacia and aplastic bone disease in aluminum-related osteodystrophy. ( Andress, DL; Coburn, JW; Endres, DB; Maloney, NA; Sherrard, DJ, 1987)
"Body disproportion and severe degree of osteopenia (BMD SDSBA -2."1.31Persistence of delayed adrenarche in boys with thalassemia. ( De Martinis, F; De Terlizzi, F; Di Maio, S; Esposito, G; Filosa, A, 2001)
"Nevertheless, osteopenia remains the main negative factor of thalassemia."1.29[The evolutionary effects of therapy on the skeletal lesions in beta-thalassemia]. ( Bariani, L; Castaldi, G; Orzincolo, C; Scutellari, PN, 1994)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19906 (37.50)18.7374
1990's5 (31.25)18.2507
2000's4 (25.00)29.6817
2010's1 (6.25)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hernández-Sánchez, A1
Tejada-González, P1
Arteta-Jiménez, M1
Kashiwagi, T1
Kurihara, S2
Nakazawa, R2
Vogiatzi, MG1
Autio, KA1
Mait, JE1
Schneider, R1
Lesser, M1
Giardina, PJ1
Orzincolo, C1
Castaldi, G1
Bariani, L1
Scutellari, PN1
Sulková, S1
Filosa, A1
Di Maio, S1
Esposito, G1
De Martinis, F1
De Terlizzi, F1
Marumo, F1
Mazzaferro, S1
Coen, G1
Ballanti, P1
Costantini, S1
Bondatti, F1
Giordano, R1
Manni, M1
Pasquali, M1
Perruzza, I1
Sardella, D1
Klein, GL1
Snodgrass, WR1
Griffin, MP1
Miller, NL1
Alfrey, AC2
Coburn, JW2
Norris, KC1
Sherrard, DJ2
Bia, M1
Llach, F1
Slatopolsky, E1
Andress, DL1
Maloney, NA1
Endres, DB1
Williams, JW1
Vera, SR1
Peters, TG1
Luther, RW1
Bhattacharya, S1
Spears, H1
Graham, A1
Pitcock, JA1
Crawford, AJ1
Palmieri, GM1
Charhon, SA1
Chavassieux, PM1
Chapuy, MC1
Traeger, J1
Meunier, PJ1

Reviews

4 reviews available for deferoxamine and Low Bone Density

ArticleYear
Aluminium in parenteral nutrition: a systematic review.
    European journal of clinical nutrition, 2013, Volume: 67, Issue:3

    Topics: Aluminum; Alzheimer Disease; Bone Diseases, Metabolic; Deferoxamine; Dyslipidemias; Humans; Iron; Ke

2013
[Aluminum and iron deposition in dialysis patients].
    Nihon rinsho. Japanese journal of clinical medicine, 2004, Volume: 62 Suppl 6

    Topics: Aluminum; Aluminum Hydroxide; Anemia; Bone Diseases, Metabolic; Contraindications; Deferoxamine; Dem

2004
[The K/DOQI guidelines on diagnosis and treatment of aluminum bone disease in hemodialysis patients].
    Clinical calcium, 2004, Volume: 14, Issue:5

    Topics: Aluminum; Biomarkers; Bone Diseases, Metabolic; Deferoxamine; Hemodiafiltration; Hemodialysis Soluti

2004
Deferoxamine therapy of bone aluminum accumulation in renal dialysis patients.
    Nutrition reviews, 1985, Volume: 43, Issue:4

    Topics: Adolescent; Adult; Aluminum; Bone and Bones; Bone Diseases, Metabolic; Chelating Agents; Child; Chil

1985

Other Studies

12 other studies available for deferoxamine and Low Bone Density

ArticleYear
Low bone mineral density in adolescents with beta-thalassemia.
    Annals of the New York Academy of Sciences, 2005, Volume: 1054

    Topics: Adolescent; Adult; Anthropometry; beta-Thalassemia; Blood Transfusion; Bone Density; Bone Diseases,

2005
[The evolutionary effects of therapy on the skeletal lesions in beta-thalassemia].
    La Radiologia medica, 1994, Volume: 87, Issue:4

    Topics: Adolescent; Adult; beta-Thalassemia; Blood Transfusion; Bone and Bones; Bone Diseases, Metabolic; Ch

1994
[Aluminum osteopathy--experience with therapy].
    Vnitrni lekarstvi, 1993, Volume: 39, Issue:5

    Topics: Aluminum; Bone Diseases, Metabolic; Deferoxamine; Female; Humans; Male; Middle Aged; Poisoning; Rena

1993
Persistence of delayed adrenarche in boys with thalassemia.
    Journal of pediatric endocrinology & metabolism : JPEM, 2001, Volume: 14, Issue:4

    Topics: Adolescent; Age Determination by Skeleton; Blood Transfusion; Body Height; Body Mass Index; Bone Den

2001
[Dialysis bone disease associated with other factors].
    Nihon rinsho. Japanese journal of clinical medicine, 1992, Volume: 50 Suppl

    Topics: Aluminum; Amyloidosis; Bone Diseases, Metabolic; Calcium Carbonate; Deferoxamine; Humans; Iron; Kidn

1992
[Aluminum and iron deposition in dialysis patients].
    Nihon rinsho. Japanese journal of clinical medicine, 1992, Volume: 50 Suppl

    Topics: Aluminum; Anemia; Bone Diseases, Metabolic; Deferoxamine; Erythropoietin; Humans; Iron; Kidney Failu

1992
Deferoxamine test and PTH serum levels are useful not to recognize but to exclude aluminum-related bone disease.
    Nephron, 1992, Volume: 61, Issue:2

    Topics: Adult; Aluminum; Biopsy; Bone and Bones; Bone Diseases, Metabolic; Deferoxamine; Diagnostic Errors;

1992
Hypocalcemia complicating deferoxamine therapy in an infant with parenteral nutrition-associated aluminum overload: evidence for a role of aluminum in the bone disease of infants.
    Journal of pediatric gastroenterology and nutrition, 1989, Volume: 9, Issue:3

    Topics: Adult; Aluminum; Bone Diseases, Metabolic; Calcium; Deferoxamine; Female; Humans; Hypocalcemia; Infa

1989
Toxic effects of aluminum in end-stage renal disease: discussion of a case.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 1988, Volume: 12, Issue:3

    Topics: Aluminum; Bone Diseases, Metabolic; Brain Diseases; Deferoxamine; Female; Hemodialysis, Home; Humans

1988
Osteomalacia and aplastic bone disease in aluminum-related osteodystrophy.
    The Journal of clinical endocrinology and metabolism, 1987, Volume: 65, Issue:1

    Topics: Adult; Aluminum; Bone Diseases, Metabolic; Deferoxamine; Female; Humans; Male; Middle Aged; Osteomal

1987
Biliary excretion of aluminum in aluminum osteodystrophy with liver disease.
    Annals of internal medicine, 1986, Volume: 104, Issue:6

    Topics: Adult; Aluminum; Aluminum Hydroxide; Bile; Bone and Bones; Bone Diseases, Metabolic; Chronic Disease

1986
High bone turnover associated with an aluminum-induced impairment of bone mineralization.
    Bone, 1986, Volume: 7, Issue:5

    Topics: Aluminum; Biopsy; Bone and Bones; Bone Diseases, Metabolic; Deferoxamine; Humans; Hyperparathyroidis

1986