deferoxamine has been researched along with Liver Failure in 4 studies
Deferoxamine: Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
desferrioxamine B : An acyclic desferrioxamine that is butanedioic acid in which one of the carboxy groups undergoes formal condensation with the primary amino group of N-(5-aminopentyl)-N-hydroxyacetamide and the second carboxy group undergoes formal condensation with the hydroxyamino group of N(1)-(5-aminopentyl)-N(1)-hydroxy-N(4)-[5-(hydroxyamino)pentyl]butanediamide. It is a siderophore native to Streptomyces pilosus biosynthesised by the DesABCD enzyme cluster as a high affinity Fe(III) chelator.
Liver Failure: Severe inability of the LIVER to perform its normal metabolic functions, as evidenced by severe JAUNDICE and abnormal serum levels of AMMONIA; BILIRUBIN; ALKALINE PHOSPHATASE; ASPARTATE AMINOTRANSFERASE; LACTATE DEHYDROGENASES; and albumin/globulin ratio. (Blakiston's Gould Medical Dictionary, 4th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| " In thalassemia major patients, combined therapy with desferrioxamine and deferiprone has maximized tissue iron removal and may reduce the overall occurrence of hemosiderotic heart failure." | 3.73 | Transfusional hemosiderosis and combined chelation therapy in sickle thalassemia. ( Aessopos, A; Andriopoulos, P; Deftereos, S; Farmakis, D; Moyssakis, I; Polonifi, K; Tsironi, M, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kim, KM | 1 |
| Cho, SS | 1 |
| Ki, SH | 1 |
| Panatto, JP | 1 |
| Jeremias, IC | 1 |
| Ferreira, GK | 1 |
| Ramos, AC | 1 |
| Rochi, N | 1 |
| Gonçalves, CL | 1 |
| Daufenbach, JF | 1 |
| Jeremias, GC | 1 |
| Carvalho-Silva, M | 1 |
| Rezin, GT | 1 |
| Scaini, G | 1 |
| Streck, EL | 1 |
| Tsironi, M | 1 |
| Polonifi, K | 1 |
| Deftereos, S | 1 |
| Farmakis, D | 1 |
| Andriopoulos, P | 1 |
| Moyssakis, I | 1 |
| Aessopos, A | 1 |
| Heffron, T | 1 |
| Pillen, T | 1 |
| Welch, D | 1 |
| Asolati, M | 1 |
| Smallwood, G | 1 |
| Hagedorn, P | 1 |
| Fasola, C | 1 |
| Solis, D | 1 |
| Rodrigues, J | 1 |
| DePaolo, J | 1 |
| Spivey, J | 1 |
| Martinez, E | 1 |
| Henry, S | 1 |
| Romero, R | 1 |
1 review available for deferoxamine and Liver Failure
| Article | Year |
|---|---|
Emerging roles of ferroptosis in liver pathophysiology.
Topics: Animals; Antineoplastic Agents; Caffeic Acids; Carcinoma, Hepatocellular; Cycloheximide; Cyclohexyla | 2020 |
3 other studies available for deferoxamine and Liver Failure
| Article | Year |
|---|---|
Inhibition of mitochondrial respiratory chain in the brain of rats after hepatic failure induced by acetaminophen.
Topics: Acetaminophen; Acetylcysteine; Analgesics, Non-Narcotic; Animals; Antioxidants; Brain; Deferoxamine; | 2011 |
Transfusional hemosiderosis and combined chelation therapy in sickle thalassemia.
Topics: Adult; Anemia, Sickle Cell; beta-Thalassemia; Blood Transfusion; Chelation Therapy; Deferiprone; Def | 2005 |
Medical and surgical treatment of neonatal hemochromatosis: single center experience.
Topics: Antioxidants; Chelation Therapy; Deferoxamine; Disease Progression; Drug Therapy, Combination; Facto | 2007 |