deferoxamine has been researched along with Leukemia L5178 in 2 studies
Deferoxamine: Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
desferrioxamine B : An acyclic desferrioxamine that is butanedioic acid in which one of the carboxy groups undergoes formal condensation with the primary amino group of N-(5-aminopentyl)-N-hydroxyacetamide and the second carboxy group undergoes formal condensation with the hydroxyamino group of N(1)-(5-aminopentyl)-N(1)-hydroxy-N(4)-[5-(hydroxyamino)pentyl]butanediamide. It is a siderophore native to Streptomyces pilosus biosynthesised by the DesABCD enzyme cluster as a high affinity Fe(III) chelator.
Leukemia L5178: An experimental lymphocytic leukemia of mice.
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 2 (100.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Kruszewski, M | 2 |
Green, MH | 1 |
Lowe, JE | 1 |
Szumiel, I | 2 |
Iwaneńko, T | 1 |
Bouzyk, E | 1 |
2 other studies available for deferoxamine and Leukemia L5178
Article | Year |
---|---|
Comparison of effects of iron and calcium chelators on the response of L5178Y sublines to X-rays and H2O2.
Topics: Aminoquinolines; Animals; Antimutagenic Agents; Calcium; Cell Survival; Chelating Agents; Deferoxami | 1995 |
Chelating of iron and copper alters properties of DNA in L5178Y cells, as revealed by the comet assay.
Topics: Animals; Cell Count; Cell Nucleus; Cell Survival; Chelating Agents; Copper; Deferoxamine; DNA Damage | 1999 |