deferoxamine has been researched along with Koch's Disease in 2 studies
Deferoxamine: Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
desferrioxamine B : An acyclic desferrioxamine that is butanedioic acid in which one of the carboxy groups undergoes formal condensation with the primary amino group of N-(5-aminopentyl)-N-hydroxyacetamide and the second carboxy group undergoes formal condensation with the hydroxyamino group of N(1)-(5-aminopentyl)-N(1)-hydroxy-N(4)-[5-(hydroxyamino)pentyl]butanediamide. It is a siderophore native to Streptomyces pilosus biosynthesised by the DesABCD enzyme cluster as a high affinity Fe(III) chelator.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Tuberculosis is the single biggest infectious killer in the world and presents a major global health challenge." | 1.56 | Desferrioxamine Supports Metabolic Function in Primary Human Macrophages Infected With ( Basdeo, SA; Cox, DJ; Gogan, KM; Keane, J; Kenny, C; McQuaid, K; Ó Maoldomhnaigh, C; O'Leary, S; O'Neill, LA; O'Sullivan, MJ; O'Sullivan, MP; Phelan, JJ; Tazoll, SC, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 2 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Terán, G | 1 |
| Li, H | 1 |
| Catrina, SB | 1 |
| Liu, R | 1 |
| Brighenti, S | 1 |
| Zheng, X | 1 |
| Grünler, J | 1 |
| Nylén, S | 1 |
| Carow, B | 1 |
| Rottenberg, ME | 1 |
| Phelan, JJ | 1 |
| McQuaid, K | 1 |
| Kenny, C | 1 |
| Gogan, KM | 1 |
| Cox, DJ | 1 |
| Basdeo, SA | 1 |
| O'Leary, S | 1 |
| Tazoll, SC | 1 |
| Ó Maoldomhnaigh, C | 1 |
| O'Sullivan, MP | 1 |
| O'Neill, LA | 1 |
| O'Sullivan, MJ | 1 |
| Keane, J | 1 |
2 other studies available for deferoxamine and Koch's Disease
| Article | Year |
|---|---|
High Glucose and Carbonyl Stress Impair HIF-1-Regulated Responses and the Control of Mycobacterium tuberculosis in Macrophages.
Topics: Animals; Deferoxamine; Glucose; Hypoxia; Hypoxia-Inducible Factor 1; Macrophages; Magnesium Oxide; M | 2022 |
Desferrioxamine Supports Metabolic Function in Primary Human Macrophages Infected With
Topics: Blood Donors; Cell Count; Cell Survival; Cells, Cultured; Deferoxamine; Glycolysis; Host-Pathogen In | 2020 |