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deferoxamine and Kidney Failure

deferoxamine has been researched along with Kidney Failure in 4 studies

Deferoxamine: Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
desferrioxamine B : An acyclic desferrioxamine that is butanedioic acid in which one of the carboxy groups undergoes formal condensation with the primary amino group of N-(5-aminopentyl)-N-hydroxyacetamide and the second carboxy group undergoes formal condensation with the hydroxyamino group of N(1)-(5-aminopentyl)-N(1)-hydroxy-N(4)-[5-(hydroxyamino)pentyl]butanediamide. It is a siderophore native to Streptomyces pilosus biosynthesised by the DesABCD enzyme cluster as a high affinity Fe(III) chelator.

Kidney Failure: A severe irreversible decline in the ability of kidneys to remove wastes, concentrate URINE, and maintain ELECTROLYTE BALANCE; BLOOD PRESSURE; and CALCIUM metabolism.

Research Excerpts

ExcerptRelevanceReference
" DFO at a dosing level equivalent to 10-fold of that of DXR was useful to obtain protective effects."1.31The preventive role of deferoxamine against acute doxorubicin-induced cardiac, renal and hepatic toxicity in rats. ( Al-Rikabi, AC; Najjar, TA; Saad, SY, 2001)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (50.00)18.2507
2000's2 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kozaki, K1
Egawa, H1
Garcia-Kennedy, R1
Cox, KL1
Lindsay, J1
Esquivel, CO1
Wang, G1
Zhu, P1
Wang, S1
Saad, SY1
Najjar, TA1
Al-Rikabi, AC1
Fernández-Martín, JL1
Fernández-Soto, I1
Acuña, G1
Cannata-Andía, JB1

Other Studies

4 other studies available for deferoxamine and Kidney Failure

ArticleYear
Hepatic failure due to massive iron ingestion successfully treated with liver transplantation.
    Clinical transplantation, 1995, Volume: 9, Issue:2

    Topics: Child, Preschool; Deferoxamine; Female; Follow-Up Studies; Gastric Lavage; Hemofiltration; Hepatic E

1995
[The causes, diagnosis and treatment of aluminum toxicity in patients with chronic renal failure undergoing dialysis].
    Zhonghua nei ke za zhi, 1996, Volume: 35, Issue:1

    Topics: Aluminum; Bone and Bones; Deferoxamine; Humans; Poisoning; Renal Dialysis; Renal Insufficiency; Side

1996
The preventive role of deferoxamine against acute doxorubicin-induced cardiac, renal and hepatic toxicity in rats.
    Pharmacological research, 2001, Volume: 43, Issue:3

    Topics: Analysis of Variance; Animals; Chelating Agents; Chemical and Drug Induced Liver Injury; Deferoxamin

2001
Bone aluminum uptake in uremic rats receiving intraperitoneal iron.
    Biological trace element research, 2001,Winter, Volume: 84, Issue:1-3

    Topics: Aluminum; Animals; Bone and Bones; Deferoxamine; Erythropoietin; Iron; Male; Rats; Rats, Wistar; Ren

2001