deferoxamine has been researched along with Keloid in 2 studies
Deferoxamine: Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
desferrioxamine B : An acyclic desferrioxamine that is butanedioic acid in which one of the carboxy groups undergoes formal condensation with the primary amino group of N-(5-aminopentyl)-N-hydroxyacetamide and the second carboxy group undergoes formal condensation with the hydroxyamino group of N(1)-(5-aminopentyl)-N(1)-hydroxy-N(4)-[5-(hydroxyamino)pentyl]butanediamide. It is a siderophore native to Streptomyces pilosus biosynthesised by the DesABCD enzyme cluster as a high affinity Fe(III) chelator.
Keloid: A sharply elevated, irregularly shaped, progressively enlarging scar resulting from formation of excessive amounts of collagen in the dermis during connective tissue repair. It is differentiated from a hypertrophic scar (CICATRIX, HYPERTROPHIC) in that the former does not spread to surrounding tissues.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Keloids are an excessive accumulation of extracellular matrix." | 1.32 | Mechanisms of hypoxic regulation of plasminogen activator inhibitor-1 gene expression in keloid fibroblasts. ( Ann, DK; Bertolami, CN; Kelly, AP; Le, AD; Messadi, DV; Tuan, TL; Wu, Y; Zhang, Q, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, Q | 1 |
| Wu, Y | 1 |
| Ann, DK | 1 |
| Messadi, DV | 1 |
| Tuan, TL | 1 |
| Kelly, AP | 1 |
| Bertolami, CN | 1 |
| Le, AD | 1 |
| Vincent, AS | 1 |
| Phan, TT | 1 |
| Mukhopadhyay, A | 1 |
| Lim, HY | 1 |
| Halliwell, B | 1 |
| Wong, KP | 1 |
2 other studies available for deferoxamine and Keloid
| Article | Year |
|---|---|
Mechanisms of hypoxic regulation of plasminogen activator inhibitor-1 gene expression in keloid fibroblasts.
Topics: Adult; Cell Hypoxia; Cells, Cultured; Cycloheximide; Dactinomycin; Deferoxamine; Female; Fibroblasts | 2003 |
Human skin keloid fibroblasts display bioenergetics of cancer cells.
Topics: Adenosine Triphosphate; Adolescent; Adult; Antimutagenic Agents; Cell Hypoxia; Cells, Cultured; Chil | 2008 |