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deferoxamine and Injuries, Radiation

deferoxamine has been researched along with Injuries, Radiation in 8 studies

Deferoxamine: Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
desferrioxamine B : An acyclic desferrioxamine that is butanedioic acid in which one of the carboxy groups undergoes formal condensation with the primary amino group of N-(5-aminopentyl)-N-hydroxyacetamide and the second carboxy group undergoes formal condensation with the hydroxyamino group of N(1)-(5-aminopentyl)-N(1)-hydroxy-N(4)-[5-(hydroxyamino)pentyl]butanediamide. It is a siderophore native to Streptomyces pilosus biosynthesised by the DesABCD enzyme cluster as a high affinity Fe(III) chelator.

Research Excerpts

ExcerptRelevanceReference
"Deferoxamine treatment presents a potential therapeutic avenue through which to target impaired wound healing in patients following radiotherapy."1.72Transdermal deferoxamine administration improves excisional wound healing in chronically irradiated murine skin. ( Abbas, DB; Churukian, A; Griffin, M; Guardino, N; Guo, JL; Gurtner, GC; Lavin, CV; Lintel, H; Longaker, MT; Momeni, A; Wan, DC, 2022)
"Deferoxamine is a U."1.42Deferoxamine mitigates radiation-induced tissue injury in a rat irradiated TRAM flap model. ( Best, R; Das, A; Lin, KY; Mericli, AF; Rodeheaver, G; Rodeheaver, P, 2015)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19901 (12.50)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's6 (75.00)24.3611
2020's1 (12.50)2.80

Authors

AuthorsStudies
Lintel, H1
Abbas, DB1
Lavin, CV1
Griffin, M1
Guo, JL1
Guardino, N1
Churukian, A1
Gurtner, GC1
Momeni, A2
Longaker, MT1
Wan, DC2
Urlaub, KM1
Lynn, JV1
Carey, EG1
Nelson, NS3
Polyatskaya, Y2
Donneys, A4
Mazzoli, AC1
Buchman, SR4
Dassoulas, KR1
Mericli, AF2
Wang, JS1
Lei, SS1
Kim, T1
Cottler, PS1
Lin, KY2
Das, A1
Best, R1
Rodeheaver, P1
Rodeheaver, G1
Blough, JT1
Perosky, JE2
Deshpande, SS2
Kang, SY1
Felice, PA1
Figueredo, C2
Peterson, JR1
Kozloff, KM2
Levi, B1
Chepeha, DB1
Rodriguez, JJ1
Vasseli, CA1
Ratliff, HC1
Rapp, S1
Wesbey, GE1
Engelstad, BL1
Brasch, RC1

Other Studies

8 other studies available for deferoxamine and Injuries, Radiation

ArticleYear
Transdermal deferoxamine administration improves excisional wound healing in chronically irradiated murine skin.
    Journal of translational medicine, 2022, 06-17, Volume: 20, Issue:1

    Topics: Animals; Cicatrix; Collagen; Deferoxamine; Humans; Mice; Nitric Oxide; Radiation Injuries; Skin; Wou

2022
Histologic Improvements in Irradiated Bone Through Pharmaceutical Intervention in Mandibular Distraction Osteogenesis.
    Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 2018, Volume: 76, Issue:12

    Topics: Amifostine; Animals; Deferoxamine; Drug Therapy, Combination; Male; Mandible; Osteogenesis, Distract

2018
Treatment With Topical Deferoxamine Improves Cutaneous Vascularity and Tissue Pliability in an Irradiated Animal Model of Tissue Expander-Based Breast Reconstruction.
    Annals of plastic surgery, 2019, Volume: 82, Issue:1

    Topics: Administration, Topical; Animals; Breast Neoplasms; Deferoxamine; Disease Models, Animal; Female; Ma

2019
Deferoxamine mitigates radiation-induced tissue injury in a rat irradiated TRAM flap model.
    Plastic and reconstructive surgery, 2015, Volume: 135, Issue:1

    Topics: Animals; Deferoxamine; Disease Models, Animal; Male; Radiation Injuries; Rats; Rats, Sprague-Dawley;

2015
Translational treatment paradigm for managing non-unions secondary to radiation injury utilizing adipose derived stem cells and angiogenic therapy.
    Head & neck, 2016, Volume: 38 Suppl 1

    Topics: Adipose Tissue; Animals; Debridement; Deferoxamine; Fractures, Ununited; Mandible; Radiation Injurie

2016
Prevention of radiation-induced bone pathology through combined pharmacologic cytoprotection and angiogenic stimulation.
    Bone, 2016, Volume: 84

    Topics: Amifostine; Angiography; Animals; Biomechanical Phenomena; Bone Density; Bone Diseases; Cytoprotecti

2016
Clinical Use of Deferoxamine in Distraction Osteogenesis of Irradiated Bone.
    The Journal of craniofacial surgery, 2016, Volume: 27, Issue:4

    Topics: Animals; Bone Regeneration; Deferoxamine; Humans; Male; Maxilla; Maxillary Diseases; Osteogenesis, D

2016
Paramagnetic pharmaceuticals for magnetic resonance imaging.
    Physiological chemistry and physics and medical NMR, 1984, Volume: 16, Issue:2

    Topics: Abdomen; Adult; Animals; Brain; Contrast Media; Deferoxamine; Electron Spin Resonance Spectroscopy;

1984