deferoxamine has been researched along with Injuries, Eye in 3 studies
Deferoxamine: Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
desferrioxamine B : An acyclic desferrioxamine that is butanedioic acid in which one of the carboxy groups undergoes formal condensation with the primary amino group of N-(5-aminopentyl)-N-hydroxyacetamide and the second carboxy group undergoes formal condensation with the hydroxyamino group of N(1)-(5-aminopentyl)-N(1)-hydroxy-N(4)-[5-(hydroxyamino)pentyl]butanediamide. It is a siderophore native to Streptomyces pilosus biosynthesised by the DesABCD enzyme cluster as a high affinity Fe(III) chelator.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Physiopathologic mechanisms associated with these toxic effects are yet unclear and, besides discontinuation of the drug, when possible, there is no current validated treatment once visual loss is present." | 2.49 | [Ocular toxicity of drugs]. ( Audo, I, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (66.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Audo, I | 1 |
| Luongo, E | 1 |
| Falbe-Hansen, I | 1 |
1 review available for deferoxamine and Injuries, Eye
| Article | Year |
|---|---|
[Ocular toxicity of drugs].
Topics: Anticonvulsants; Antimalarials; Deferoxamine; Drug-Related Side Effects and Adverse Reactions; Eye I | 2013 |
2 other studies available for deferoxamine and Injuries, Eye
| Article | Year |
|---|---|
[Treatment of ocular siderosis with desferrioxamine B].
Topics: Adolescent; Adult; Deferoxamine; Eye Diseases; Eye Foreign Bodies; Eye Injuries; Humans; Male; Sider | 1968 |
Treatment of ocular siderosis and haemochromatosis with desferrioxamine.
Topics: Deferoxamine; Eye Diseases; Eye Foreign Bodies; Eye Injuries; Hemorrhage; Humans; Injections, Intram | 1966 |