deferoxamine has been researched along with Infections in 5 studies
Deferoxamine: Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
desferrioxamine B : An acyclic desferrioxamine that is butanedioic acid in which one of the carboxy groups undergoes formal condensation with the primary amino group of N-(5-aminopentyl)-N-hydroxyacetamide and the second carboxy group undergoes formal condensation with the hydroxyamino group of N(1)-(5-aminopentyl)-N(1)-hydroxy-N(4)-[5-(hydroxyamino)pentyl]butanediamide. It is a siderophore native to Streptomyces pilosus biosynthesised by the DesABCD enzyme cluster as a high affinity Fe(III) chelator.
Infections: Invasion of the host organism by microorganisms or their toxins or by parasites that can cause pathological conditions or diseases.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Iron overload is known to exacerbate many infectious diseases." | 1.36 | The role of iron and chelators on infections in iron overload and non iron loaded conditions: prospects for the design of new antimicrobial therapies. ( Kolnagou, A; Kontoghiorghes, GJ; Petrikkos, G; Skiada, A, 2010) |
| "Our results demonstrate that scrapie infection leads to changes in cellular iron metabolism, affecting both total cellular and cytosolic free iron, and the activities and expression of major regulators of cellular iron homeostasis." | 1.33 | Changed iron regulation in scrapie-infected neuroblastoma cells. ( Bedecs, K; Fernaeus, S; Hälldin, J; Land, T, 2005) |
| "aureus infection in thigh." | 1.30 | Dual radiolabeled liposomes: biodistribution studies and localization of focal sites of infection in rats. ( Awasthi, VD; Goins, B; Klipper, R; Phillips, WT, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (40.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kontoghiorghes, GJ | 1 |
| Kolnagou, A | 1 |
| Skiada, A | 1 |
| Petrikkos, G | 1 |
| Fernaeus, S | 1 |
| Hälldin, J | 1 |
| Bedecs, K | 1 |
| Land, T | 1 |
| Economidou, J | 1 |
| Awasthi, VD | 1 |
| Goins, B | 1 |
| Klipper, R | 1 |
| Phillips, WT | 1 |
| Stacher, A | 1 |
2 reviews available for deferoxamine and Infections
| Article | Year |
|---|---|
Problems related to treatment of beta-thalassaemia major.
Topics: Adolescent; Adult; Bone Diseases; Child; Child, Preschool; Deferoxamine; Encephalitis; Female; Hormo | 1982 |
[Diseases caused by iron metabolism disorders and their therapy].
Topics: Adult; Anemia, Hypochromic; Anti-Glomerular Basement Membrane Disease; Bloodletting; Deferoxamine; D | 1969 |
3 other studies available for deferoxamine and Infections
| Article | Year |
|---|---|
The role of iron and chelators on infections in iron overload and non iron loaded conditions: prospects for the design of new antimicrobial therapies.
Topics: Anti-Infective Agents; Benzoates; Deferasirox; Deferiprone; Deferoxamine; Humans; Infections; Iron; | 2010 |
Changed iron regulation in scrapie-infected neuroblastoma cells.
Topics: Animals; Blotting, Southern; Blotting, Western; Cell Line, Tumor; Deferoxamine; Electrophoretic Mobi | 2005 |
Dual radiolabeled liposomes: biodistribution studies and localization of focal sites of infection in rats.
Topics: Animals; Chelating Agents; Deferoxamine; Glutathione; Image Processing, Computer-Assisted; Indium Ra | 1998 |