Page last updated: 2024-10-25

deferoxamine and Infections, Yersinia

deferoxamine has been researched along with Infections, Yersinia in 46 studies

Deferoxamine: Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
desferrioxamine B : An acyclic desferrioxamine that is butanedioic acid in which one of the carboxy groups undergoes formal condensation with the primary amino group of N-(5-aminopentyl)-N-hydroxyacetamide and the second carboxy group undergoes formal condensation with the hydroxyamino group of N(1)-(5-aminopentyl)-N(1)-hydroxy-N(4)-[5-(hydroxyamino)pentyl]butanediamide. It is a siderophore native to Streptomyces pilosus biosynthesised by the DesABCD enzyme cluster as a high affinity Fe(III) chelator.

Research Excerpts

ExcerptRelevanceReference
" We describe a case of this unusual condition in a 17-year-old male patient with thalassemia intermedia requiring transfusion, who was also taking deferoxamine."3.68Yersinia enterocolitica infection with ileal perforation associated with iron overload and deferoxamine therapy. ( deSa, D; Gately, J; Mazzoleni, G; Riddell, RH, 1991)
" The severe toxic effects on vision, hearing and growth are all more likely at higher doses of DF and there appears to be partial protection against them by iron overload."2.38The toxic effects of desferrioxamine. ( Huehns, ER; Porter, JB, 1989)
"Our patient's unusual presentation of intussusception was secondary to the mass effect caused by lymphoid hyperplasia, specifically hypertrophied Peyer's patches in the ileum caused by Y enterocolitica infection."1.31Intussusception due to Yersinia enterocolitica enterocolitis in a patient with beta-thalassemia. ( Hansen, MG; Levy, M; Pearl, G, 2001)
"Deferoxamine therapy was withheld, and antibiotic therapy was administered with subsequent clinical improvement."1.29Yersinia enterocolitica infection in a patient with sickle cell disease after exposure to chitterlings. ( Casella, JF; Nataro, JP; Stoddard, JJ; Wechsler, DS, 1994)
"Systemic yersiniosis was further confirmed by the finding of antibodies to Yersinia enterocolitica O5."1.29[Hepatic abscess due to Yersinia in a child with thalassemia]. ( Brunel, F; Croize, J; Durand, C; François, P; Jeannoel, P, 1993)

Research

Studies (46)

TimeframeStudies, this research(%)All Research%
pre-199025 (54.35)18.7374
1990's15 (32.61)18.2507
2000's6 (13.04)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Greco, L1
Marino, F1
Gentile, A1
Catalano, G1
Angilletta, D1
Robins-Browne, RM4
Prpic, JK4
Gordts, B1
Rummens, E1
deMeirleir, L1
Butzler, JP1
Scharnetzky, M1
König, R1
Lakomek, M1
Tillmann, W1
Schröter, W1
Paitel, JF1
Guerci, AP1
Dorvaux, V1
Lederlin, P1
Chambers, CE1
Sokol, PA1
Autenrieth, IB2
Reissbrodt, R1
Saken, E1
Berner, R1
Vogel, U1
Rabsch, W1
Heesemann, J1
Stoddard, JJ1
Wechsler, DS1
Nataro, JP1
Casella, JF1
Chandler, ND1
Parisi, MT1
Blei, F1
Puder, DR1
Brunel, F1
François, P1
Durand, C1
Croize, J1
Jeannoel, P1
Adamkiewicz, TV1
Berkovitch, M1
Krishnan, C1
Polsinelli, C1
Kermack, D1
Olivieri, NF1
Sparling, PF1
Schubert, S1
Pallister, C1
Rotstein, OD1
Nikolova, S1
Wesselinova, D1
Vesselinova, A1
Hansen, MG1
Pearl, G1
Levy, M1
Lesic, B1
Foulon, J1
Carniel, E1
de los Toyos, JR1
Menéndez, P1
Sampedro, A1
Hardisson, C1
Hoen, B2
Kessler, M2
Cabanne, JF1
Dubot, P1
Mazzoleni, G1
deSa, D1
Gately, J1
Riddell, RH1
Abcarian, PW1
Demas, BE1
Pierron, H1
Gillet, R1
Perrimond, H1
Broudeur, JC1
Soudry, G1
Porter, JB1
Huehns, ER1
Freedman, MH2
Bentur, Y1
Koren, G1
Hughes, RT1
Keidan, J1
Janmohamed, R1
Leyland, MJ1
Chiu, HY1
Flynn, DM1
Hoffbrand, AV1
Politis, D1
Kelly, D1
Price, E1
Wright, V1
Walker-Smith, J1
Rossiter, M1
Warren, JJ1
Waterlot, Y1
Vanherweghem, JL2
Dumont-Senaneuch, C1
Floret, D1
Philippe, N1
Masters, AP1
Hopkinson, RB1
Renoult, E1
Jonon, B1
Stuart, SJ1
Hadjiminas, JM1
Eggleston, SM1
Huang, CB1
Löhr, H1
Mofenson, HC1
Caraccio, TR1
Sharieff, N1
Chiesa, C1
Pacifico, L1
Renzulli, F1
Midulla, M1
Garlaschi, L1
Boelaert, JR2
van Landuyt, HW1
Valcke, YJ1
Cantinieaux, B1
Lornoy, WF1
Moreillon, P1
Vandepitte, JM2
Vergauwe, PL1
Gallant, T1
Vellend, H1
Francombe, WH1
Boyce, N1
Wood, C1
Holdsworth, S1
Thomson, NM1
Atkins, RC1
Davey, RB1

Reviews

4 reviews available for deferoxamine and Infections, Yersinia

ArticleYear
Yersinia enterocolitica bacteremia in a chronically transfused patient with sickle cell anemia. Case report and review of the literature.
    The American journal of pediatric hematology/oncology, 1993, Volume: 15, Issue:4

    Topics: Adolescent; Anemia, Sickle Cell; Bacteremia; Blood Transfusion; Ceftriaxone; Deferoxamine; Disease S

1993
The toxic effects of desferrioxamine.
    Bailliere's clinical haematology, 1989, Volume: 2, Issue:2

    Topics: Animals; Blood-Brain Barrier; Deferoxamine; Disease Susceptibility; Eye Diseases; Growth Disorders;

1989
Biological and toxic properties of deferoxamine.
    Progress in clinical and biological research, 1989, Volume: 309

    Topics: Cataract; Cell Division; Deferoxamine; DNA; Drug Hypersensitivity; Hearing Disorders; Humans; Pulmon

1989
Yersiniae and iron. A study in host-parasite relationships.
    Contributions to microbiology and immunology, 1987, Volume: 9

    Topics: Deferoxamine; Humans; Iron; Siderosis; Virulence; Yersinia; Yersinia Infections

1987

Trials

1 trial available for deferoxamine and Infections, Yersinia

ArticleYear
[Infectious risks in patients with renal failure on hemodialysis. Importance of iron overload and deferoxamine].
    Presse medicale (Paris, France : 1983), 1991, Apr-20, Volume: 20, Issue:15

    Topics: Bacterial Infections; Deferoxamine; Ferritins; Humans; Incidence; Iron; Kidney Failure, Chronic; Lis

1991

Other Studies

41 other studies available for deferoxamine and Infections, Yersinia

ArticleYear
Yersinia enterocolitica ileocolitis in beta-thalassemic patients.
    Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland, 2006, Volume: 8, Issue:6

    Topics: Adult; Appendectomy; beta-Thalassemia; Comorbidity; Crohn Disease; Deferoxamine; Female; Humans; Mal

2006
Desferrioxamine and systemic yersiniosis.
    Lancet (London, England), 1983, Dec-10, Volume: 2, Issue:8363

    Topics: Animals; Deferoxamine; Humans; Iron; Mice; Thalassemia; Yersinia enterocolitica; Yersinia Infections

1983
Yersinia pseudotuberculosis septicaemia in thalassaemia major.
    Lancet (London, England), 1984, Jan-07, Volume: 1, Issue:8367

    Topics: Adolescent; Deferoxamine; Female; Humans; Sepsis; Thalassemia; Yersinia Infections; Yersinia pseudot

1984
Prophylaxis of systemic yersinosis in thalassaemia major.
    Lancet (London, England), 1984, Apr-07, Volume: 1, Issue:8380

    Topics: Child; Deferoxamine; Female; Humans; Risk; Sepsis; Thalassemia; Yersinia Infections

1984
[Yersinia enterocolitica septicemia, iron overload and deferoxamine].
    La Revue de medecine interne, 1995, Volume: 16, Issue:9

    Topics: Anemia, Sideroblastic; Bacteremia; Cephalosporins; Deferoxamine; Humans; Iron; Male; Middle Aged; Ye

1995
Comparison of siderophore production and utilization in pathogenic and environmental isolates of Yersinia enterocolitica.
    Journal of clinical microbiology, 1994, Volume: 32, Issue:1

    Topics: Animals; Bacterial Outer Membrane Proteins; Deferoxamine; Environmental Microbiology; Ferric Compoun

1994
Desferrioxamine-promoted virulence of Yersinia enterocolitica in mice depends on both desferrioxamine type and mouse strain.
    The Journal of infectious diseases, 1994, Volume: 169, Issue:3

    Topics: Animals; Cell Division; Deferoxamine; Lymphocyte Activation; Male; Mice; Mice, Inbred BALB C; Mice,

1994
Yersinia enterocolitica infection in a patient with sickle cell disease after exposure to chitterlings.
    The American journal of pediatric hematology/oncology, 1994, Volume: 16, Issue:2

    Topics: Anemia, Sickle Cell; Animals; Child; Deferoxamine; Female; Food Microbiology; Humans; Intestines; Sw

1994
Radiological case of the month. Yersinia enterocolitica masquerading as appendicitis.
    Archives of pediatrics & adolescent medicine, 1994, Volume: 148, Issue:5

    Topics: Abscess; Appendicitis; beta-Thalassemia; Biopsy; Child; Deferoxamine; Diagnosis, Differential; Hemog

1994
[Hepatic abscess due to Yersinia in a child with thalassemia].
    Pediatrie, 1993, Volume: 48, Issue:2

    Topics: Adolescent; beta-Thalassemia; Deferoxamine; Humans; Iron; Liver Abscess; Male; Yersinia enterocoliti

1993
Infection due to Yersinia enterocolitica in a series of patients with beta-thalassemia: incidence and predisposing factors.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1998, Volume: 27, Issue:6

    Topics: Adolescent; Adult; beta-Thalassemia; Canada; Causality; Chelating Agents; Child; Child, Preschool; C

1998
Iron and infection.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1998, Volume: 27, Issue:6

    Topics: beta-Thalassemia; Canada; Causality; Chelating Agents; Deferoxamine; Humans; Incidence; Yersinia ent

1998
Conjugation of hydroxyethyl starch to desferrioxamine (DFO) modulates the dual role of DFO in Yersinia enterocolitica infection.
    Clinical and diagnostic laboratory immunology, 2000, Volume: 7, Issue:3

    Topics: Animals; Cell Division; Chelating Agents; Deferoxamine; Drug Compounding; Hydroxyethyl Starch Deriva

2000
Yersinia enterocolitica as a cause of intra-abdominal abscess: the role of iron.
    Canadian journal of surgery. Journal canadien de chirurgie, 2001, Volume: 44, Issue:2

    Topics: Abdominal Abscess; Abdominal Pain; Adult; Anti-Bacterial Agents; beta-Thalassemia; Chelating Agents;

2001
Pretreatment of guinea-pigs with iron or desferal influences the course of Yersinia enterocolitica infections.
    Journal of veterinary medicine. B, Infectious diseases and veterinary public health, 2001, Volume: 48, Issue:3

    Topics: Administration, Oral; Animals; Antigens, Bacterial; Chelating Agents; Deferoxamine; Electrophoresis,

2001
Intussusception due to Yersinia enterocolitica enterocolitis in a patient with beta-thalassemia.
    Archives of pathology & laboratory medicine, 2001, Volume: 125, Issue:11

    Topics: beta-Thalassemia; Child, Preschool; Deferoxamine; Enterocolitis; Humans; Hypertrophy; Ileum; Intussu

2001
Comparison of the effects of deferiprone versus deferoxamine on growth and virulence of Yersinia enterocolitica.
    Antimicrobial agents and chemotherapy, 2002, Volume: 46, Issue:6

    Topics: 2,2'-Dipyridyl; Animals; Chelating Agents; Culture Media; Deferiprone; Deferoxamine; Iron Chelating

2002
Yersinia enterocolitica serotype 0:3-induced arthritis in mice: microbiological and histopathological information.
    APMIS : acta pathologica, microbiologica, et immunologica Scandinavica, 1992, Volume: 100, Issue:5

    Topics: Animals; Arthritis, Infectious; Bone Marrow; Cartilage, Articular; Deferoxamine; Disease Models, Ani

1992
[Severe Yersinia enterocolitica infections in kidney failure patients under dialysis].
    Presse medicale (Paris, France : 1983), 1991, Nov-16, Volume: 20, Issue:38

    Topics: Adolescent; Adult; Deferoxamine; Female; Humans; Immune Tolerance; Iron; Kidney Failure, Chronic; Ma

1991
Yersinia enterocolitica infection with ileal perforation associated with iron overload and deferoxamine therapy.
    Digestive diseases and sciences, 1991, Volume: 36, Issue:8

    Topics: Adolescent; Blood Transfusion; Deferoxamine; Humans; Ileal Diseases; Intestinal Perforation; Iron; L

1991
Systemic Yersinia enterocolitica infection associated with iron overload and deferoxamine therapy.
    AJR. American journal of roentgenology, 1991, Volume: 157, Issue:4

    Topics: Blood Transfusion; Child, Preschool; Deferoxamine; Gastroenteritis; Humans; Male; Mesenteric Lymphad

1991
[Yersinia infection and hemoglobin disorder. Apropos of 4 cases].
    Pediatrie, 1990, Volume: 45, Issue:6

    Topics: Anemia, Sickle Cell; Child; Deferoxamine; Female; Humans; Iron; Male; Thalassemia; Yersinia enteroco

1990
Yersinia and iron.
    Lancet (London, England), 1987, Apr-18, Volume: 1, Issue:8538

    Topics: Adult; Deferoxamine; Female; Humans; Iron; Yersinia; Yersinia Infections

1987
Infection with Yersinia enterocolitica in patients with iron overload.
    British medical journal (Clinical research ed.), 1986, Jan-11, Volume: 292, Issue:6513

    Topics: Adult; Anemia, Sideroblastic; Blood Transfusion; Deferoxamine; Female; Hemosiderosis; Humans; Male;

1986
Yersinia and iron overload.
    British medical journal (Clinical research ed.), 1986, Feb-08, Volume: 292, Issue:6517

    Topics: Deferoxamine; Female; Humans; Infant; Thalassemia; Yersinia enterocolitica; Yersinia Infections

1986
Why deferoxamine therapy predisposes to Yersinia sepsis.
    Acta haematologica, 1987, Volume: 77, Issue:3

    Topics: Deferoxamine; Humans; Yersinia Infections

1987
[Desferrioxamine in hemodialysis as the cause of Yersinia enterocolitica septicemia].
    Presse medicale (Paris, France : 1983), 1985, Mar-23, Volume: 14, Issue:12

    Topics: Deferoxamine; Female; Humans; Middle Aged; Renal Dialysis; Yersinia enterocolitica; Yersinia Infecti

1985
[Fatal Yersinia enterocolitica septic shock in a child with chronic anemia].
    Pediatrie, 1988, Volume: 43, Issue:6

    Topics: Anemia, Hemolytic, Congenital; Child, Preschool; Deferoxamine; Humans; Male; Risk Factors; Shock, Se

1988
Yersinia enterocolitica septicaemia.
    Intensive care medicine, 1988, Volume: 14, Issue:5

    Topics: Adult; Deferoxamine; Hemosiderosis; Humans; Sepsis; Thalassemia; Yersinia enterocolitica; Yersinia I

1988
Septicemia due to Yersinia enterocolitica in a long-term hemodialysis patient after a single desferrioxamine administration.
    Nephron, 1988, Volume: 50, Issue:4

    Topics: Deferoxamine; Humans; Male; Middle Aged; Renal Dialysis; Sepsis; Yersinia enterocolitica; Yersinia I

1988
Yersiniosis in acutely iron-loaded children treated with desferrioxamine.
    The Journal of antimicrobial chemotherapy, 1988, Volume: 21, Issue:5

    Topics: Child; Deferoxamine; Humans; Infant; Iron; Sepsis; Yersinia Infections

1988
Comment: deferoxamine-induced sepsis.
    Drug intelligence & clinical pharmacy, 1987, Volume: 21, Issue:10

    Topics: Deferoxamine; Humans; Yersinia Infections

1987
[Yersinia septicemia in children with thalassaemia major].
    Changgeng yi xue za zhi, 1987, Jun-20, Volume: 10, Issue:2

    Topics: Child; Child, Preschool; Deferoxamine; Female; Hemosiderosis; Humans; Male; Risk Factors; Sepsis; Th

1987
Iron sepsis: Yersinia enterocolitica septicemia possibly caused by an overdose of iron.
    The New England journal of medicine, 1987, Apr-23, Volume: 316, Issue:17

    Topics: Acute Disease; Deferoxamine; Diseases in Twins; Female; Humans; Infant; Iron; Male; Sepsis; Yersinia

1987
Yersinia hepatic abscesses and iron overload.
    JAMA, 1987, Jun-19, Volume: 257, Issue:23

    Topics: Child; Child, Preschool; Deferoxamine; Female; Humans; Iron; Male; Thalassemia; Yersinia enterocolit

1987
The role of iron overload in Yersinia enterocolitica and Yersinia pseudotuberculosis bacteremia in hemodialysis patients.
    The Journal of infectious diseases, 1987, Volume: 156, Issue:2

    Topics: Adult; Aged; Deferoxamine; Female; Ferritins; Humans; Iron; Male; Middle Aged; Renal Dialysis; Sepsi

1987
Mucormycosis infection in dialysis patients.
    Annals of internal medicine, 1987, Volume: 107, Issue:5

    Topics: Deferoxamine; Humans; Iron; Mucormycosis; Renal Dialysis; Yersinia Infections

1987
Yersinia sepsis in patients with iron overload treated with deferoxamine.
    The New England journal of medicine, 1986, Jun-19, Volume: 314, Issue:25

    Topics: Adult; Deferoxamine; Female; Humans; Iron; Thalassemia; Yersinia enterocolitica; Yersinia Infections

1986
Life-threatening sepsis complicating heavy metal chelation therapy with desferrioxamine.
    Australian and New Zealand journal of medicine, 1985, Volume: 15, Issue:5

    Topics: Adult; Deferoxamine; Humans; Iron; Male; Renal Dialysis; Sepsis; Yersinia Infections

1985
Effects of iron and desferrioxamine on infections with Yersinia enterocolitica.
    Infection and immunity, 1985, Volume: 47, Issue:3

    Topics: Animals; Deferoxamine; Dose-Response Relationship, Drug; Guinea Pigs; Iron; Mice; Transferrin; Yersi

1985
In vitro assessment of virulence in Yersinia enterocolitica and related species.
    Journal of clinical microbiology, 1985, Volume: 22, Issue:1

    Topics: Agglutination Tests; Animals; Blood Bactericidal Activity; Calcium; Congo Red; Deferoxamine; Iron-De

1985