deferoxamine has been researched along with Hyaline Membrane Disease in 2 studies
Deferoxamine: Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
desferrioxamine B : An acyclic desferrioxamine that is butanedioic acid in which one of the carboxy groups undergoes formal condensation with the primary amino group of N-(5-aminopentyl)-N-hydroxyacetamide and the second carboxy group undergoes formal condensation with the hydroxyamino group of N(1)-(5-aminopentyl)-N(1)-hydroxy-N(4)-[5-(hydroxyamino)pentyl]butanediamide. It is a siderophore native to Streptomyces pilosus biosynthesised by the DesABCD enzyme cluster as a high affinity Fe(III) chelator.
Hyaline Membrane Disease: A respiratory distress syndrome in newborn infants, usually premature infants with insufficient PULMONARY SURFACTANTS. The disease is characterized by the formation of a HYALINE-like membrane lining the terminal respiratory airspaces (PULMONARY ALVEOLI) and subsequent collapse of the lung (PULMONARY ATELECTASIS).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Deferoxamine treatment was initiated at 10 mg/kg per hour but, after the precipitous death of the first animal, was progressively reduced to 1." | 5.28 | Toxic effects associated with the administration of deferoxamine in the premature baboon with hyaline membrane disease. ( Coalson, JJ; deLemos, JA; deLemos, RA; Gerstmann, DR; Null, DM; Roberts, RJ, 1990) |
| "Deferoxamine treatment was initiated at 10 mg/kg per hour but, after the precipitous death of the first animal, was progressively reduced to 1." | 1.28 | Toxic effects associated with the administration of deferoxamine in the premature baboon with hyaline membrane disease. ( Coalson, JJ; deLemos, JA; deLemos, RA; Gerstmann, DR; Null, DM; Roberts, RJ, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Adamson, IY | 1 |
| Sienko, A | 1 |
| Tenenbein, M | 1 |
| deLemos, RA | 1 |
| Roberts, RJ | 1 |
| Coalson, JJ | 1 |
| deLemos, JA | 1 |
| Null, DM | 1 |
| Gerstmann, DR | 1 |
2 other studies available for deferoxamine and Hyaline Membrane Disease
| Article | Year |
|---|---|
Pulmonary toxicity of deferoxamine in iron-poisoned mice.
Topics: Animals; Atmosphere Exposure Chambers; Bronchoalveolar Lavage Fluid; Deferoxamine; Disease Models, A | 1993 |
Toxic effects associated with the administration of deferoxamine in the premature baboon with hyaline membrane disease.
Topics: Animals; Cardiovascular Diseases; Deferoxamine; Drug Evaluation, Preclinical; Female; Humans; Hyalin | 1990 |