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deferoxamine and Hepatic Failure

deferoxamine has been researched along with Hepatic Failure in 4 studies

Deferoxamine: Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
desferrioxamine B : An acyclic desferrioxamine that is butanedioic acid in which one of the carboxy groups undergoes formal condensation with the primary amino group of N-(5-aminopentyl)-N-hydroxyacetamide and the second carboxy group undergoes formal condensation with the hydroxyamino group of N(1)-(5-aminopentyl)-N(1)-hydroxy-N(4)-[5-(hydroxyamino)pentyl]butanediamide. It is a siderophore native to Streptomyces pilosus biosynthesised by the DesABCD enzyme cluster as a high affinity Fe(III) chelator.

Research Excerpts

ExcerptRelevanceReference
" In thalassemia major patients, combined therapy with desferrioxamine and deferiprone has maximized tissue iron removal and may reduce the overall occurrence of hemosiderotic heart failure."3.73Transfusional hemosiderosis and combined chelation therapy in sickle thalassemia. ( Aessopos, A; Andriopoulos, P; Deftereos, S; Farmakis, D; Moyssakis, I; Polonifi, K; Tsironi, M, 2005)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (50.00)29.6817
2010's1 (25.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Kim, KM1
Cho, SS1
Ki, SH1
Panatto, JP1
Jeremias, IC1
Ferreira, GK1
Ramos, AC1
Rochi, N1
Gonçalves, CL1
Daufenbach, JF1
Jeremias, GC1
Carvalho-Silva, M1
Rezin, GT1
Scaini, G1
Streck, EL1
Tsironi, M1
Polonifi, K1
Deftereos, S1
Farmakis, D1
Andriopoulos, P1
Moyssakis, I1
Aessopos, A1
Heffron, T1
Pillen, T1
Welch, D1
Asolati, M1
Smallwood, G1
Hagedorn, P1
Fasola, C1
Solis, D1
Rodrigues, J1
DePaolo, J1
Spivey, J1
Martinez, E1
Henry, S1
Romero, R1

Reviews

1 review available for deferoxamine and Hepatic Failure

ArticleYear
Emerging roles of ferroptosis in liver pathophysiology.
    Archives of pharmacal research, 2020, Volume: 43, Issue:10

    Topics: Animals; Antineoplastic Agents; Caffeic Acids; Carcinoma, Hepatocellular; Cycloheximide; Cyclohexyla

2020

Other Studies

3 other studies available for deferoxamine and Hepatic Failure

ArticleYear
Inhibition of mitochondrial respiratory chain in the brain of rats after hepatic failure induced by acetaminophen.
    Molecular and cellular biochemistry, 2011, Volume: 350, Issue:1-2

    Topics: Acetaminophen; Acetylcysteine; Analgesics, Non-Narcotic; Animals; Antioxidants; Brain; Deferoxamine;

2011
Transfusional hemosiderosis and combined chelation therapy in sickle thalassemia.
    European journal of haematology, 2005, Volume: 75, Issue:4

    Topics: Adult; Anemia, Sickle Cell; beta-Thalassemia; Blood Transfusion; Chelation Therapy; Deferiprone; Def

2005
Medical and surgical treatment of neonatal hemochromatosis: single center experience.
    Pediatric transplantation, 2007, Volume: 11, Issue:4

    Topics: Antioxidants; Chelation Therapy; Deferoxamine; Disease Progression; Drug Therapy, Combination; Facto

2007