deferoxamine has been researched along with Hemosiderosis in 198 studies
Deferoxamine: Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
desferrioxamine B : An acyclic desferrioxamine that is butanedioic acid in which one of the carboxy groups undergoes formal condensation with the primary amino group of N-(5-aminopentyl)-N-hydroxyacetamide and the second carboxy group undergoes formal condensation with the hydroxyamino group of N(1)-(5-aminopentyl)-N(1)-hydroxy-N(4)-[5-(hydroxyamino)pentyl]butanediamide. It is a siderophore native to Streptomyces pilosus biosynthesised by the DesABCD enzyme cluster as a high affinity Fe(III) chelator.
Hemosiderosis: Conditions in which there is a generalized increase in the iron stores of body tissues, particularly of liver and the MONONUCLEAR PHAGOCYTE SYSTEM, without demonstrable tissue damage. The name refers to the presence of stainable iron in the tissue in the form of hemosiderin.
| Excerpt | Relevance | Reference |
|---|---|---|
| " deferoxamine in 586 patients with beta-thalessemia and transfusional hemosiderosis." | 9.12 | Deferasirox for the treatment of chronic iron overload in transfusional hemosiderosis. ( Al-Fayoumi, S; Castillo, S; Chakraborti, T; Choudary, J; Frankewich, R; Kacuba, A; Pazdur, R; Rieves, D; Robie-Suh, K; Shashaty, G; Weiss, K, 2006) |
| " We report a randomized double-blind study of the dose-response relationship of intravenous DFO in six subjects with sickle cell anemia and severe transfusion-induced hemosiderosis (serum ferritin 4100 to 14,176 ng/ml)." | 6.67 | Iron chelation by deferoxamine in sickle cell patients with severe transfusion-induced hemosiderosis: a randomized, double-blind study of the dose-response relationship. ( Dixon, DJ; Hambidge, KM; Lane, PA; Mellman, DL; Peterson, VM; Silliman, CC, 1993) |
| "We enrolled nine patients with thalassemia major complicated by some degree of myocardial dysfunction." | 5.33 | Regression of myocardial dysfunction after switching from desferrioxamine to deferiprone therapy in beta-thalassemia major patients. ( Chang, JS; Huang, YC; Peng, CT; Wu, KH, 2006) |
| " deferoxamine in 586 patients with beta-thalessemia and transfusional hemosiderosis." | 5.12 | Deferasirox for the treatment of chronic iron overload in transfusional hemosiderosis. ( Al-Fayoumi, S; Castillo, S; Chakraborti, T; Choudary, J; Frankewich, R; Kacuba, A; Pazdur, R; Rieves, D; Robie-Suh, K; Shashaty, G; Weiss, K, 2006) |
| "Deferoxamine mesylate (DFO) is the most commonly used iron-chelating agent to treat transfusion-related hemosiderosis." | 4.91 | Functional and Structural Abnormalities in Deferoxamine Retinopathy: A Review of the Literature. ( Barteselli, G; Dell'Arti, L; Di Nicola, M; Ratiglia, R; Viola, F, 2015) |
| "Deferasirox, a tridentate oral chelator approved for the treatment of chronic iron overload due to blood transfusions, offers a promising alternative for patients unwilling or unable to comply with deferoxamine therapy." | 4.84 | Deferasirox. ( Stumpf, JL, 2007) |
| " In thalassemia major patients, combined therapy with desferrioxamine and deferiprone has maximized tissue iron removal and may reduce the overall occurrence of hemosiderotic heart failure." | 3.73 | Transfusional hemosiderosis and combined chelation therapy in sickle thalassemia. ( Aessopos, A; Andriopoulos, P; Deftereos, S; Farmakis, D; Moyssakis, I; Polonifi, K; Tsironi, M, 2005) |
| "The incidence of cardiomyopathy was monitored in a 6-year follow-up study involving 56 transfused thalassemia patients treated with deferoxamine (DFO), deferiprone (L1) or their combination." | 3.73 | Low serum ferritin levels are misleading for detecting cardiac iron overload and increase the risk of cardiomyopathy in thalassemia patients. The importance of cardiac iron overload monitoring using magnetic resonance imaging T2 and T2*. ( Economides, C; Eracleous, E; Kolnagou, A; Kontoghiorghes, GJ, 2006) |
| "Eight patients (16 eyes) developed ocular toxicity while undergoing intravenous deferoxamine mesylate (Desferal) chelation therapy for transfusional hemosiderosis." | 3.67 | Deferoxamine (Desferal)-induced toxic retinal pigmentary degeneration and presumed optic neuropathy. ( Jiji, R; Lakhanpal, V; Schocket, SS, 1984) |
| "Aluminum-associated osteomalacia and transfusion-induced hemosiderosis developed in an anephric patient receiving long-term maintenance treatment with continuous ambulatory peritoneal dialysis." | 3.67 | Deferoxamine-enhanced fecal losses of aluminum and iron in a patient undergoing continuous ambulatory peritoneal dialysis. ( Kurtz, SB; McCarthy, JT; Mussman, GV, 1987) |
| " Deferoxamine-induced urinary excretion of iron was considerably less than that reported in patients with thalassemia major who were receiving regular blood transfusions." | 3.66 | Iron burden in sickle cell anemia. ( O'Brien, RT, 1978) |
| "Adult patients with transfusional hemosiderosis were given ascorbic acid and treated with the iron chelator, desferrioxamine B." | 3.65 | Treatment of iron overload in adults with continuous parenteral desferrioxamine. ( Bunn, HF; Cooper, B; Moloney, WC; Nathan, DG; Propper, RD; Rosenthal, DS, 1977) |
| " We report a randomized double-blind study of the dose-response relationship of intravenous DFO in six subjects with sickle cell anemia and severe transfusion-induced hemosiderosis (serum ferritin 4100 to 14,176 ng/ml)." | 2.67 | Iron chelation by deferoxamine in sickle cell patients with severe transfusion-induced hemosiderosis: a randomized, double-blind study of the dose-response relationship. ( Dixon, DJ; Hambidge, KM; Lane, PA; Mellman, DL; Peterson, VM; Silliman, CC, 1993) |
| " The interdialytic half-life of ferrioxamine was 2." | 2.67 | Pharmacokinetics of aluminoxamine and ferrioxamine and dose finding of desferrioxamine in haemodialysis patients. ( Becaus, I; Boelaert, JR; D'Haese, PC; De Broe, ME; Lamberts, LV; Verpooten, GA, 1992) |
| " A long term administration of chelating agents may prevent organ damage by surplus of iron as well as improve cardiac and liver function in iron overloaded patients." | 2.39 | [Current possibilities in the therapy of iron overload]. ( Cermák, J, 1994) |
| "Hemochromatosis is a syndrome which, when fully expressed, is manifested by melanoderma , diabetes mellitus, and liver cirrhosis, with iron overload involving parenchymal and reticuloendothelial cells in many organ systems." | 2.36 | Iron overload disorders: natural history, pathogenesis, diagnosis, and therapy. ( Kellermeyer, RW; McLaren, GD; Muir, WA, 1983) |
| "A 28-year-old man with beta-thalassemia major, splenectomy, hepatitis C, and hemosiderosis who presented with increasing dyspnea on exertion was diagnosed with pulmonary hypertension." | 1.33 | Pulmonary hypertension and beta-thalassemia major: report of a case, its treatment, and a review of the literature. ( Farber, HW; Tam, DH, 2006) |
| "We enrolled nine patients with thalassemia major complicated by some degree of myocardial dysfunction." | 1.33 | Regression of myocardial dysfunction after switching from desferrioxamine to deferiprone therapy in beta-thalassemia major patients. ( Chang, JS; Huang, YC; Peng, CT; Wu, KH, 2006) |
| "Juvenile hemochromatosis is a rare genetic disorder that causes iron overload." | 1.31 | Juvenile hemochromatosis associated with B-thalassemia treated by phlebotomy and recombinant human erythropoietin. ( Brunello, F; Camaschella, C; De Gobbi, M; Mazza, U; Paccotti, P; Pasquero, P, 2000) |
| "Dobutamine is a sympathomimetic drug (beta 1 agonist) that increases myocardial contractility and at high doses also systolic arterial blood pressure and heart rate." | 1.29 | Cardiac study by dobutamine stress echocardiography in thalassemic patients. ( Agostini, A; Angelucci, E; Cesaroni, P; Lucarelli, G; Mariotti, E; Sgarbi, E, 1993) |
| " Quantitative data regarding optimal dosage and application of DFO in RDT patients are not yet available." | 1.27 | Therapy and monitoring of hypersiderosis in chronic renal insufficiency. ( Baldamus, CA; Bechstein, PB; Fassbinder, W; Hilfenhaus, M; Koch, KM; Schmidt, H, 1984) |
| "0." | 1.27 | Iron overload, but not treatment with desferrioxamine favours the development of septicemia in patients on maintenance hemodialysis. ( Schaefer, K; Seifert, A; von Herrath, D, 1987) |
| "Hemochromatosis was noted in 4 patients (group II)." | 1.26 | [Iron-overload in patients on maintenance hemodialysis: diagnostic criteria, indications and treatment by desferrioxamine (author's transl)]. ( Bonn, F; Guezennec, M; Simon, P; Tanquerel, T, 1981) |
| "Since patients with thalassemia are not growth hormone deficient, the data suggest the possibility of defective hepatic biosynthesis of somatomedin." | 1.26 | Depressed serum somatomedin activity in beta-thalassemia. ( Graziano, JH; Hilgartner, MW; Levine, LS; Markenson, AL; New, MI; Saenger, P; Schwartz, E, 1980) |
| "One case of transfusion haemochromatosis with haemolytic anaemia and renal failure gave an Fv value of 8,019 mug." | 1.24 | Differential ferrioxamine test in idiopathic haemochromatosis and transfusional haemosiderosis. ( Brunström, GM; Fielding, J; O'Shaughnessy, MC, 1966) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 148 (74.75) | 18.7374 |
| 1990's | 26 (13.13) | 18.2507 |
| 2000's | 19 (9.60) | 29.6817 |
| 2010's | 5 (2.53) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dessì, C | 2 |
| Leoni, G | 1 |
| Moi, P | 1 |
| Danjou, F | 1 |
| Follesa, I | 1 |
| Foschini, ML | 1 |
| Morittu, M | 1 |
| Zappu, A | 1 |
| Defraia, E | 1 |
| Bina, P | 1 |
| Cunico, A | 1 |
| Civolani, A | 1 |
| Podda, RA | 1 |
| Origa, R | 1 |
| Di Nicola, M | 1 |
| Barteselli, G | 1 |
| Dell'Arti, L | 1 |
| Ratiglia, R | 1 |
| Viola, F | 1 |
| McLeod, C | 1 |
| Fleeman, N | 1 |
| Kirkham, J | 1 |
| Bagust, A | 1 |
| Boland, A | 1 |
| Chu, P | 1 |
| Dickson, R | 1 |
| Dundar, Y | 1 |
| Greenhalgh, J | 1 |
| Modell, B | 1 |
| Olujohungbe, A | 1 |
| Telfer, P | 1 |
| Walley, T | 1 |
| Yap, J | 1 |
| O'Connor, C | 1 |
| Kirby, M | 1 |
| Guindi, M | 1 |
| Roberts, EA | 1 |
| Cario, H | 2 |
| Grosse, R | 1 |
| Janssen, G | 1 |
| Jarisch, A | 1 |
| Meerpohl, J | 1 |
| Strauss, G | 1 |
| Alpendurada, F | 1 |
| Smith, GC | 1 |
| Carpenter, JP | 1 |
| Nair, SV | 1 |
| Tanner, MA | 1 |
| Banya, W | 1 |
| Galanello, R | 1 |
| Walker, JM | 1 |
| Pennell, DJ | 1 |
| Brown, GC | 1 |
| Patton, WN | 1 |
| Tapp, HE | 1 |
| Taylor, DJ | 1 |
| St Pierre, TG | 1 |
| WOEHLER, F | 2 |
| DE VRIES, SI | 1 |
| GOUDSMIT, R | 1 |
| SCHRETLEN, ED | 1 |
| WALSH, JR | 5 |
| MASS, RE | 3 |
| SMITH, FW | 2 |
| LANGE, V | 2 |
| HILDNER, FJ | 2 |
| MONTO, RW | 2 |
| REBUCK, JW | 2 |
| SCURO, LA | 1 |
| BROCCIA, G | 1 |
| DOBRILLA, G | 2 |
| TAGLIAMONTE, A | 1 |
| UNSELD, DW | 1 |
| VENTURA, S | 1 |
| COLI, L | 1 |
| RITTER, M | 1 |
| SUNDERMANN, A | 1 |
| PANZRAM, G | 1 |
| Schmidt, D | 1 |
| Finke, J | 1 |
| Tsironi, M | 1 |
| Polonifi, K | 1 |
| Deftereos, S | 1 |
| Farmakis, D | 1 |
| Andriopoulos, P | 1 |
| Moyssakis, I | 1 |
| Aessopos, A | 1 |
| Mwanda, OW | 1 |
| Otieno, CF | 1 |
| Abdalla, FK | 1 |
| Gaziev, J | 1 |
| Sodani, P | 1 |
| Polchi, P | 1 |
| Andreani, M | 1 |
| Lucarelli, G | 2 |
| Tam, DH | 1 |
| Farber, HW | 1 |
| Tavecchia, L | 1 |
| Masera, N | 1 |
| Russo, P | 1 |
| Cirò, A | 1 |
| Vincenzi, A | 1 |
| Vimercati, C | 1 |
| Masera, G | 1 |
| Kolnagou, A | 2 |
| Economides, C | 1 |
| Eracleous, E | 1 |
| Kontoghiorghes, GJ | 2 |
| Huang, YC | 1 |
| Chang, JS | 1 |
| Wu, KH | 1 |
| Peng, CT | 1 |
| Shashaty, G | 1 |
| Frankewich, R | 1 |
| Chakraborti, T | 1 |
| Choudary, J | 1 |
| Al-Fayoumi, S | 1 |
| Kacuba, A | 1 |
| Castillo, S | 1 |
| Robie-Suh, K | 1 |
| Rieves, D | 1 |
| Weiss, K | 1 |
| Pazdur, R | 1 |
| Stumpf, JL | 1 |
| Gancz, AY | 1 |
| Wellehan, JF | 1 |
| Boutette, J | 1 |
| Malka, S | 1 |
| Lee, SE | 1 |
| Smith, DA | 1 |
| Taylor, M | 1 |
| Vichinsky, E | 1 |
| Pakbaz, Z | 1 |
| Onyekwere, O | 1 |
| Porter, J | 1 |
| Swerdlow, P | 1 |
| Coates, T | 1 |
| Lane, P | 1 |
| Files, B | 1 |
| Mueller, BU | 1 |
| Coïc, L | 1 |
| Forni, GL | 1 |
| Fischer, R | 2 |
| Marks, P | 1 |
| Rofail, D | 1 |
| Abetz, L | 1 |
| Baladi, JF | 1 |
| Kondur, AK | 1 |
| Li, T | 1 |
| Vaitkevicius, P | 1 |
| Afonso, L | 1 |
| Thompson, RB | 1 |
| Owen, DM | 1 |
| Bell, WN | 1 |
| Wöhler, F | 2 |
| Apte, SV | 1 |
| Poggio, GL | 1 |
| Lucioni, F | 1 |
| Kattamis, C | 1 |
| Fitsialos, J | 1 |
| Sinopoulou, C | 1 |
| Hehlmann, R | 1 |
| Schmitz, H | 1 |
| Krüger, K | 1 |
| North, ML | 1 |
| Lang, JM | 1 |
| Bergerat, JP | 1 |
| Giron, C | 1 |
| Oberling, F | 1 |
| Mayer, S | 1 |
| McLaren, GD | 1 |
| Muir, WA | 1 |
| Kellermeyer, RW | 1 |
| Kol'tsova, GN | 2 |
| Mel'nikovskaia, NN | 1 |
| Likhodzievskiĭ, KG | 1 |
| Rozenberg, GIa | 1 |
| Strohmeyer, G | 2 |
| Stremmel, W | 1 |
| Krüger, N | 3 |
| Kijewski, H | 1 |
| König, R | 2 |
| Tillmann, W | 4 |
| Schröter, W | 4 |
| Hilfenhaus, M | 1 |
| Koch, KM | 1 |
| Bechstein, PB | 1 |
| Schmidt, H | 1 |
| Fassbinder, W | 1 |
| Baldamus, CA | 1 |
| Andres, J | 2 |
| Stobbe, H | 1 |
| Lakhanpal, V | 1 |
| Schocket, SS | 1 |
| Jiji, R | 1 |
| Erttmann, R | 1 |
| Hausdorf, G | 1 |
| Landbeck, G | 1 |
| Cheung, PJ | 1 |
| Nigrelli, RF | 1 |
| Ruggieri, GD | 1 |
| Gold, K | 1 |
| Baiardi, JC | 1 |
| Propper, RD | 3 |
| Siller, V | 1 |
| Frank, M | 1 |
| Simon, M | 2 |
| Hespel, JP | 1 |
| Brissot, P | 2 |
| Fauchet, R | 1 |
| Edan, G | 1 |
| Le Reun, M | 1 |
| Le Mignon, L | 1 |
| Genetet, B | 1 |
| Bourel, M | 2 |
| Ley, TJ | 1 |
| Griffith, P | 1 |
| Nienhuis, AW | 2 |
| Waters, AK | 1 |
| McCarthy, JT | 2 |
| Libertin, CR | 1 |
| Mitchell, JC | 1 |
| Fairbanks, VF | 2 |
| Schröder, K | 1 |
| Pippard, MJ | 1 |
| Callender, ST | 1 |
| Finch, CA | 1 |
| Tuschy, U | 1 |
| Schmidt, U | 1 |
| Meinhold, J | 1 |
| Wutke, K | 1 |
| Ambruso, DR | 1 |
| Mahony, BS | 1 |
| Githens, JH | 1 |
| Rhoades, ED | 1 |
| Krumlovsky, FA | 3 |
| Rembold, CM | 1 |
| Roxe, DM | 2 |
| Fitzsimmons, E | 1 |
| del Greco, F | 2 |
| Lau, EH | 1 |
| Cerny, EA | 2 |
| Rahman, YE | 2 |
| Sidi, Y | 1 |
| Shaklai, M | 1 |
| Liban, E | 1 |
| Pinkhas, J | 1 |
| Janka, GE | 2 |
| Möhring, P | 1 |
| Helmig, M | 1 |
| Haas, RJ | 1 |
| Betke, K | 1 |
| Simon, P | 2 |
| Bonn, F | 1 |
| Guezennec, M | 1 |
| Tanquerel, T | 1 |
| Ceriati, F | 1 |
| Cavicchioni, C | 1 |
| Marino, IR | 1 |
| Pomponi, M | 1 |
| Saenger, P | 1 |
| Schwartz, E | 1 |
| Markenson, AL | 1 |
| Graziano, JH | 2 |
| Levine, LS | 1 |
| New, MI | 1 |
| Hilgartner, MW | 1 |
| Katz, AJ | 1 |
| Girot, R | 1 |
| Thévenin, M | 1 |
| Bouveret, JP | 1 |
| Jeannel, F | 1 |
| Rymer, JC | 1 |
| Splendiani, G | 1 |
| Tozzo, C | 1 |
| Mazzarella, V | 1 |
| Casciani, CU | 1 |
| Gabutti, V | 2 |
| Borgna-Pignatti, C | 1 |
| Cermák, J | 2 |
| Brabec, V | 1 |
| Mehta, J | 1 |
| Chablani, A | 1 |
| Reporter, R | 1 |
| Singhal, S | 1 |
| Mehta, BC | 1 |
| Hromec, A | 1 |
| Payer, J | 1 |
| Killinger, Z | 1 |
| Rybár, I | 1 |
| Rovenský, J | 1 |
| Silliman, CC | 1 |
| Peterson, VM | 1 |
| Mellman, DL | 1 |
| Dixon, DJ | 1 |
| Hambidge, KM | 1 |
| Lane, PA | 1 |
| Mariotti, E | 1 |
| Agostini, A | 1 |
| Angelucci, E | 1 |
| Cesaroni, P | 1 |
| Sgarbi, E | 1 |
| Nielsen, P | 1 |
| Engelhardt, R | 1 |
| Tondüry, P | 1 |
| Gabbe, EE | 1 |
| Giardina, PJ | 1 |
| Grady, RW | 1 |
| Levin, TL | 1 |
| Sheth, S | 1 |
| Berdon, WE | 1 |
| Ruzal-Shapiro, C | 1 |
| Piomelli, S | 1 |
| Piga, A | 1 |
| Smeets, ME | 1 |
| Vreugdenhil, G | 1 |
| Holdrinet, RS | 1 |
| Güngör, T | 1 |
| Rohrbach, E | 1 |
| Solem, E | 1 |
| Kaltwasser, JP | 1 |
| Kornhuber, B | 1 |
| Andriani, M | 1 |
| Nordio, M | 1 |
| Saporiti, E | 1 |
| Porter, JB | 1 |
| Abeysinghe, RD | 1 |
| Marshall, L | 1 |
| Hider, RC | 1 |
| Singh, S | 1 |
| Araujo, A | 1 |
| Kosaryan, M | 1 |
| MacDowell, A | 1 |
| Wickens, D | 1 |
| Puri, S | 1 |
| Wonke, B | 2 |
| Hoffbrand, AV | 5 |
| Jensen, PD | 1 |
| Heickendorff, L | 1 |
| Pedersen, B | 1 |
| Bendix-Hansen, K | 1 |
| Jensen, FT | 1 |
| Christensen, T | 1 |
| Boesen, AM | 1 |
| Ellegaard, J | 1 |
| Boelaert, JR | 3 |
| Weinberg, GA | 1 |
| Weinberg, ED | 1 |
| Minina, LT | 1 |
| Prostakova, TM | 1 |
| Meshchano, AIu | 1 |
| Bovenko, VN | 1 |
| Cantinieaux, B | 1 |
| Janssens, A | 1 |
| Lejeune, M | 1 |
| Vermylen, C | 1 |
| Kerrels, V | 1 |
| Cornu, G | 1 |
| Winand, J | 1 |
| Fondu, P | 1 |
| Stahnke, K | 1 |
| Sander, S | 1 |
| Kohne, E | 1 |
| De Gobbi, M | 1 |
| Pasquero, P | 1 |
| Brunello, F | 1 |
| Paccotti, P | 1 |
| Mazza, U | 1 |
| Camaschella, C | 1 |
| Breuer, W | 1 |
| Ermers, MJ | 1 |
| Pootrakul, P | 1 |
| Abramov, A | 1 |
| Hershko, C | 1 |
| Cabantchik, ZI | 1 |
| Hussain, MA | 2 |
| Green, N | 1 |
| Flynn, DM | 3 |
| Silvestroni, E | 1 |
| Bianco, I | 1 |
| Graziani, B | 1 |
| Carboni, C | 1 |
| Costantini, S | 1 |
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| Laulicht, M | 1 |
| Garidi, M | 1 |
| Economidou, J | 2 |
| Georgipoulou, P | 1 |
| O'Brien, RT | 2 |
| Löhr, GW | 1 |
| Batey, R | 1 |
| Scott, J | 1 |
| Jain, S | 1 |
| Sherlock, S | 1 |
| Fujiyama, N | 1 |
| Nakazawa, K | 1 |
| Cooper, B | 2 |
| Bunn, HF | 2 |
| Nathan, DG | 2 |
| Rosenthal, DS | 2 |
| Moloney, WC | 2 |
| Guilmette, RA | 1 |
| Cartei, G | 2 |
| Cazzavillan, M | 1 |
| Chisesi, T | 1 |
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| Cattell, WR | 1 |
| Ackrill, P | 1 |
| McAlister, J | 1 |
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| Verpooten, GA | 1 |
| D'Haese, PC | 1 |
| Becaus, I | 1 |
| Lamberts, LV | 1 |
| De Broe, ME | 1 |
| De Marchi, S | 1 |
| Cecchin, E | 1 |
| Perrimond, H | 1 |
| Chagnon, C | 1 |
| Moulanier, I | 1 |
| Michel, G | 1 |
| Guidicelli, H | 1 |
| Bernard, PJ | 2 |
| Fitzsimons, E | 1 |
| Eijgenraam, FJ | 2 |
| Donckerwolcke, RA | 2 |
| Muntean, W | 1 |
| Hauer, C | 1 |
| Schmid, C | 1 |
| Vullo, C | 1 |
| Di Palma, A | 1 |
| De Sanctis, V | 1 |
| Borgatti, L | 1 |
| Atti, G | 1 |
| Chiu, HY | 1 |
| Politis, D | 1 |
| Schilirò, G | 1 |
| Russo, A | 1 |
| Praga, M | 1 |
| Andrés, A | 1 |
| de la Serna, J | 1 |
| Ruilope, LM | 1 |
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| Millet, VG | 1 |
| Arnaiz, F | 1 |
| Rodicio, JL | 1 |
| van Dijken, PJ | 1 |
| Ishitoya, N | 1 |
| Gomibuchi, I | 1 |
| Fujisawa, K | 1 |
| Akatsuka, J | 1 |
| Masters, AP | 1 |
| Hopkinson, RB | 1 |
| Tielemans, C | 1 |
| Lenclud, C | 1 |
| Zdziarska, B | 1 |
| Urasiński, I | 1 |
| Winchester, JF | 1 |
| Huang, CB | 1 |
| Löhr, H | 1 |
| Seifert, A | 1 |
| von Herrath, D | 1 |
| Schaefer, K | 1 |
| Stubbe, P | 1 |
| Hakim, RM | 1 |
| Stivelman, JC | 1 |
| Schulman, G | 1 |
| Fosburg, M | 1 |
| Wolfe, L | 1 |
| Imber, MJ | 1 |
| Lazarus, JM | 1 |
| Windus, DW | 1 |
| Stokes, TJ | 1 |
| Julian, BA | 1 |
| Fenves, AZ | 1 |
| Corden, BJ | 1 |
| Kurtz, SB | 1 |
| Mussman, GV | 1 |
| Schafer, AI | 1 |
| Rabinowe, S | 1 |
| Le Boff, MS | 1 |
| Bridges, K | 1 |
| Cheron, RG | 1 |
| Dluhy, R | 1 |
| Ullrich, D | 1 |
| Khutsishvili, GE | 3 |
| Cumming, RL | 1 |
| Goldberg, A | 2 |
| Morrow, J | 1 |
| Smith, JA | 2 |
| Althoff, H | 2 |
| Vadász, G | 1 |
| Fedrizzi, G | 1 |
| Seshadri, R | 2 |
| Colebatch, JH | 2 |
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| Dyerberg, J | 2 |
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| Cerruti Mainardi, P | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Effect of Treatment With the Oral Iron Chelator Deferiprone on the Oxidative Stress of Blood Cells and on Iron Overload Status in Transfusion Dependent, Iron-overloaded Patients With Low Risk Myelodysplastic Syndrome[NCT02477631] | Phase 2 | 19 participants (Actual) | Interventional | 2016-02-29 | Completed | ||
| Predictive Value of Epicardial Fat Thickness for Disease Severity in Coronary Artery Disease Patients[NCT03308539] | 200 participants (Anticipated) | Observational | 2017-11-01 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
27 reviews available for deferoxamine and Hemosiderosis
| Article | Year |
|---|---|
Functional and Structural Abnormalities in Deferoxamine Retinopathy: A Review of the Literature.
Topics: Deferoxamine; Hemosiderosis; Humans; Iron Chelating Agents; Retina; Retinal Diseases; Retinal Vessel | 2015 |
Deferasirox for the treatment of iron overload associated with regular blood transfusions (transfusional haemosiderosis) in patients suffering with chronic anaemia: a systematic review and economic evaluation.
Topics: Anemia; Benzoates; Chronic Disease; Contraindications; Cost-Benefit Analysis; Deferasirox; Deferipro | 2009 |
Deferasirox.
Topics: Adult; Benzoates; Child; Deferasirox; Deferoxamine; Hematologic Diseases; Hemosiderosis; Humans; Iro | 2007 |
Quantification of myocardial iron overload by cardiovascular magnetic resonance imaging T2* and review of the literature.
Topics: Animals; Cardiomyopathies; Deferoxamine; Early Diagnosis; Female; Heart Failure; Hemosiderosis; Huma | 2009 |
Iron overload disorders: natural history, pathogenesis, diagnosis, and therapy.
Topics: Anemia, Hypochromic; Biological Transport; Bloodletting; Chelating Agents; Deferoxamine; Disease Mod | 1983 |
[Biologically active hydroxamic acids--iron complexons].
Topics: Animals; Chelating Agents; Chemical Phenomena; Chemistry; Deferoxamine; Hemochromatosis; Hemosideros | 1984 |
[Recommendations for therapy of juvenile thalassemia major].
Topics: Ascorbic Acid; Blood Transfusion; Child; Deferoxamine; Female; Germany, West; Greece; Hemosiderosis; | 1980 |
[Hemochromatosis].
Topics: Alleles; Biopsy; Bloodletting; Bone Marrow Examination; Chelating Agents; Deferoxamine; Diet; Genes, | 1981 |
Transfusion haemosiderosis and chelation therapy.
Topics: Adolescent; Adult; Ascorbic Acid; Blood Transfusion; Cardiomyopathies; Deferoxamine; Dose-Response R | 1982 |
Clinical manifestations and therapy of transfusional haemosiderosis.
Topics: Adolescent; Adult; Chelation Therapy; Deferoxamine; Endocrine System Diseases; Female; Heart Disease | 1994 |
[Current possibilities in the therapy of iron overload].
Topics: Deferoxamine; Hemosiderosis; Humans; Iron Chelating Agents | 1994 |
[Congenital atransferrinemia].
Topics: Adult; Anemia, Hypochromic; Blood Protein Disorders; Deferoxamine; Drug Therapy, Combination; Female | 1994 |
Chelation therapy in beta-thalassemia: the benefits and limitations of desferrioxamine.
Topics: Adolescent; Adult; Chelating Agents; Chelation Therapy; Child; Deferoxamine; Growth Disorders; Heari | 1995 |
Results of long-term iron-chelating therapy.
Topics: Adolescent; Adult; Deferoxamine; Female; Ferritins; Hemosiderosis; Humans; Iron Chelating Agents; Ma | 1996 |
Altered iron metabolism in HIV infection: mechanisms, possible consequences, and proposals for management.
Topics: AIDS-Related Opportunistic Infections; Chelating Agents; Deferoxamine; Hemosiderosis; HIV Infections | 1996 |
Iron overload: clinical and pathologic aspects in pediatrics.
Topics: Abnormalities, Multiple; Adolescent; Adult; Ascorbic Acid Deficiency; Bloodletting; Child; Child, Pr | 1977 |
[Sideroblastic anemias].
Topics: Anemia, Sideroblastic; Bone Marrow Cells; Deferoxamine; Female; Ferritins; Ferrochelatase; Folic Aci | 1978 |
Iron metabolism and chelation therapy in hemosiderosis.
Topics: Ascorbic Acid; Blood Transfusion; Chelating Agents; Deferoxamine; Diet; Gentisates; Hemochromatosis; | 1978 |
[Iron-chelating treatment].
Topics: Chelation Therapy; Deferiprone; Deferoxamine; Erythropoiesis; Hemosiderosis; Humans; Iron; Iron Chel | 1989 |
Results of long-term subcutaneous desferrioxamine therapy.
Topics: Deferoxamine; Hemosiderosis; Humans; Infusion Pumps; Infusions, Intravenous; Thalassemia | 1989 |
Management of iron overload in dialysis patients.
Topics: Animals; Deferoxamine; Hemosiderosis; Humans; Iron; Kinetics; Renal Dialysis | 1986 |
Detoxification in hemosiderosis.
Topics: Administration, Oral; Adult; Aluminum; Deferoxamine; Hemosiderosis; Humans; Injections, Intravenous; | 1985 |
Deferoxamine in measurement of iron stores.
Topics: Animals; Deferoxamine; Hemochromatosis; Hemosiderosis; Humans; Iron; Rats | 1968 |
[Deferoxamine-B, a ferriuretic chelate].
Topics: Anemia, Hypochromic; Chemical Phenomena; Chemistry; Deferoxamine; Hemochromatosis; Hemosiderosis; Hu | 1967 |
[Use of desferal in treatment of sideroses of different origin. (Literature review)].
Topics: Anemia; Anemia, Aplastic; Anemia, Sideroblastic; Animals; Bile; Child, Preschool; Deferoxamine; Hemo | 1968 |
[Diseases caused by iron metabolism disorders and their therapy].
Topics: Adult; Anemia, Hypochromic; Anti-Glomerular Basement Membrane Disease; Bloodletting; Deferoxamine; D | 1969 |
[Pathogenesis, clinical aspects and therapy of siderophilia (hemochromatosis)].
Topics: Bloodletting; Deferoxamine; Diagnosis, Differential; Diet Therapy; Hematologic Diseases; Hemochromat | 1971 |
7 trials available for deferoxamine and Hemosiderosis
| Article | Year |
|---|---|
Effective combination therapy of deferiprone and deferoxamine for the rapid clearance of excess cardiac IRON and the prevention of heart disease in thalassemia. The Protocol of the International Committee on Oral Chelators.
Topics: Administration, Oral; beta-Thalassemia; Cardiomyopathies; Chelation Therapy; Clinical Protocols; Com | 2006 |
Deferasirox for the treatment of chronic iron overload in transfusional hemosiderosis.
Topics: Adolescent; Adult; Benzoates; beta-Thalassemia; Blood Transfusion; Child; Child, Preschool; Deferasi | 2006 |
Patient-reported outcomes of deferasirox (Exjade, ICL670) versus deferoxamine in sickle cell disease patients with transfusional hemosiderosis. Substudy of a randomized open-label phase II trial.
Topics: Absenteeism; Adolescent; Adult; Anemia, Sickle Cell; Benzoates; Chelation Therapy; Child; Child, Pre | 2008 |
Oral desferrioxamine in young patients with thalassaemia.
Topics: Administration, Oral; Child, Preschool; Deferoxamine; Hemosiderosis; Humans; Thalassemia; Transfusio | 1981 |
Iron chelation by deferoxamine in sickle cell patients with severe transfusion-induced hemosiderosis: a randomized, double-blind study of the dose-response relationship.
Topics: Adolescent; Adult; Anemia, Sickle Cell; Deferoxamine; Dose-Response Relationship, Drug; Double-Blind | 1993 |
Pharmacokinetics of aluminoxamine and ferrioxamine and dose finding of desferrioxamine in haemodialysis patients.
Topics: Adult; Aged; Aluminum; Chelating Agents; Deferoxamine; Ferric Compounds; Hemosiderosis; Humans; Live | 1992 |
Hepatic computed tomography for monitoring the iron status of haemodialysis patients with haemosiderosis treated with recombinant human erythropoietin.
Topics: Adult; Aged; Chelation Therapy; Deferoxamine; Erythropoietin; Female; Ferritins; Hemosiderosis; Huma | 1991 |
164 other studies available for deferoxamine and Hemosiderosis
| Article | Year |
|---|---|
Thalassemia major between liver and heart: Where we are now.
Topics: Adolescent; Adult; beta-Thalassemia; Child; Child, Preschool; Cohort Studies; Deferiprone; Deferoxam | 2015 |
Sequential antiviral and iron chelation treatment in a teenage boy with congenital anemia, chronic hepatitis C, and secondary hemosiderosis.
Topics: Adolescent; Anemia; Antiviral Agents; Chelation Therapy; Deferoxamine; Ferritins; Hemoglobinopathies | 2009 |
[Guidelines for diagnosis and treatment of secondary iron overload in patients with congenital anemia].
Topics: Anemia, Aplastic; Anemia, Diamond-Blackfan; Anemia, Dyserythropoietic, Congenital; Anemia, Sickle Ce | 2010 |
Effects of combined deferiprone with deferoxamine on right ventricular function in thalassaemia major.
Topics: Adult; Analysis of Variance; beta-Thalassemia; Chi-Square Distribution; Deferiprone; Deferoxamine; D | 2012 |
Spin density projection-assisted R2 magnetic resonance imaging of the liver in the management of body iron stores in patients receiving multiple red blood cell transfusions: an audit and retrospective study in South Australia.
Topics: Adolescent; Adult; Aged; Benzoates; Chelation Therapy; Child; Deferasirox; Deferoxamine; Erythrocyte | 2012 |
THE TREATMENT OF HAEMOCHROMATOSIS WITH DESFERRIOXAMINE.
Topics: Anemia; Anemia, Macrocytic; Deferoxamine; Diabetes Mellitus; Ferritins; Hemochromatosis; Hemoglobins | 1963 |
[TREATMENT OF IRON LOADING WITH DESFERRIOXAMINE].
Topics: Adolescent; Anemia; Anemia, Hemolytic; Anemia, Macrocytic; Child; Deferoxamine; Geriatrics; Hemoside | 1963 |
DESFERRIOXAMINE EFFECT ON IRON EXCRETION IN HEMOCHROMATOSIS.
Topics: Deferoxamine; Hemochromatosis; Hemosiderosis; Humans; Iron; Iron Chelating Agents; Iron Isotopes; Le | 1964 |
CONGENITAL ERYTHROBLASTIC HYPOPLASIA; TREATMENT OF TRANSFUSION HEMOSIDEROSIS WITH DESFERRIOXAMINE B.
Topics: Anemia; Anemia, Aplastic; Blood Group Incompatibility; Blood Transfusion; Deferoxamine; Hemosiderosi | 1964 |
[A NEW TEST FOR ASCERTAINMENT OF STATES OF SIDEROSIS: THE DESFERRIOXAMINE TEST. PRELIMINARY RESULTS].
Topics: Anemia; Anemia, Hypochromic; Biomedical Research; Deferoxamine; Hematologic Diseases; Hemochromatosi | 1964 |
[A NEW TEST ("DESFERAL TEST") FOR THE DEMONSTRATION OF PATHOLOGICAL IRON DEPOSITS IN THE ORGANISM].
Topics: Deferoxamine; Diagnosis, Differential; Hemochromatosis; Hemosiderosis; Hepatitis; Hepatitis A; Human | 1964 |
[RESEARCH ON DESFERRIOXAMINE B. 3. THE CLINICAL USE OF DESFERRIOXAMINE B].
Topics: Anemia; Anemia, Hemolytic; Anemia, Macrocytic; Deferoxamine; Hematologic Diseases; Hemochromatosis; | 1964 |
[TREATMENT OF HEMOSIDEROSIS SECONDARY TO MULTIPLE TRANSFUSIONS, WITH SPECIAL REFERENCE TO COOLEY'S HEMOLYTIC ANEMIA].
Topics: Anemia, Hemolytic; Blood Transfusion; Deferoxamine; Drug Therapy; Hemosiderosis; Humans; Thalassemia | 1964 |
[DISEASES OF THE LUNG].
Topics: Adrenal Cortex Hormones; Child; Deferoxamine; Diagnosis, Differential; Glomerulonephritis; Granuloma | 1964 |
[TREATMENT OF HEMOCHROMATOSIS].
Topics: Deferoxamine; Drug Therapy; Hemochromatosis; Hemosiderosis; Humans; Porphyrias; Thalassemia | 1965 |
IRON CHELATION WITH DEFEROXAMINE IN HEPATIC DISEASE.
Topics: Ammonium Chloride; Biological Transport; Deferoxamine; Fluids and Secretions; Gene Expression Regula | 1965 |
[Bull's-Eye Maculopathy with Deferoxamine Treatment].
Topics: Aged; Anemia; Deferoxamine; Electroretinography; Erythrocyte Transfusion; Ferritins; Fluorescein Ang | 2004 |
Transfusional hemosiderosis and combined chelation therapy in sickle thalassemia.
Topics: Adult; Anemia, Sickle Cell; beta-Thalassemia; Blood Transfusion; Chelation Therapy; Deferiprone; Def | 2005 |
Transfusion haemosiderosis inspite of regular use of desferrioxamine: case report.
Topics: Adult; Anemia, Aplastic; Deferoxamine; Fatal Outcome; Female; Hemosiderosis; Humans; Iron Chelating | 2004 |
Bone marrow transplantation in adults with thalassemia: Treatment and long-term follow-up.
Topics: Adolescent; Adult; Azathioprine; Bone Marrow Transplantation; Busulfan; Chelation Therapy; Clinical | 2005 |
Pulmonary hypertension and beta-thalassemia major: report of a case, its treatment, and a review of the literature.
Topics: Adult; Antihypertensive Agents; beta-Thalassemia; Deferoxamine; Dyspnea; Epoprostenol; Hemosiderosis | 2006 |
Successful recovery of acute hemosiderotic heart failure in beta-thalassemia major treated with a combined regimen of desferrioxamine and deferiprone.
Topics: Adult; beta-Thalassemia; Deferiprone; Deferoxamine; Drug Therapy, Combination; Heart Failure; Hemosi | 2006 |
Low serum ferritin levels are misleading for detecting cardiac iron overload and increase the risk of cardiomyopathy in thalassemia patients. The importance of cardiac iron overload monitoring using magnetic resonance imaging T2 and T2*.
Topics: Administration, Oral; Adult; Arrhythmias, Cardiac; Cardiomyopathies; Chelation Therapy; Combined Mod | 2006 |
Regression of myocardial dysfunction after switching from desferrioxamine to deferiprone therapy in beta-thalassemia major patients.
Topics: Adolescent; Adult; beta-Thalassemia; Cardiomegaly; Cardiomyopathies; Chelation Therapy; Cohort Studi | 2006 |
Diabetes mellitus concurrent with hepatic haemosiderosis in two macaws (Ara severa, Ara militaris).
Topics: Animals; Deferoxamine; Diabetes Complications; Female; Hemosiderosis; Insulin; Liver Diseases; Male; | 2007 |
Desferal therapy in iron storage disease.
Topics: Adolescent; Adult; Anemia, Aplastic; Anemia, Sickle Cell; Deferoxamine; Female; Hemochromatosis; Hem | 1967 |
Hypersiderosis.
Topics: Deferoxamine; Hemochromatosis; Hemosiderosis; Humans; Iron; Siderosis | 1967 |
[Therapeutic results in the treatment of primary and secondary hemochromatoses with Desferal].
Topics: Anemia, Macrocytic; Blood Transfusion; Deferoxamine; Hemochromatosis; Hemosiderosis; Humans; Injecti | 1967 |
Deferoxamine and sweat iron.
Topics: Deferoxamine; Female; Hemosiderosis; Humans; Iron; Male; Sweat | 1967 |
[Study of a case of idiopathic pulmonary hemosiderosis treated with an iron chelating agent (desferoxamine B, "Desferal")].
Topics: Adolescent; Deferoxamine; Hemosiderosis; Humans; Lung Diseases; Male | 1967 |
Iron overload in cardiac valvular disease and pure red cell aplasia: treatment with desferrioxamine.
Topics: Anemia, Aplastic; Atrial Fibrillation; Cardiomegaly; Deferoxamine; Female; Hemosiderosis; Humans; Ir | 1984 |
[Iron overload in a beta thalassemia heterozygote of the intermediate type in a subject of Alsation origin. Results of iron chelation treatment].
Topics: Anemia; Deferoxamine; Female; Ferritins; Hemosiderosis; Heterozygote; HLA Antigens; HLA-A3 Antigen; | 1984 |
[Therapy of hemosiderosis with deferoxamine].
Topics: Deferoxamine; Hemosiderosis; Humans; Injections, Intravenous; Iron; Life Expectancy; Liver; Transfus | 1984 |
[Deferoxamine in hemosiderosis. Fecal iron excretion during continuous subcutaneous infusion].
Topics: Adolescent; Child; Child, Preschool; Deferoxamine; Feces; Hemosiderosis; Humans; Injections, Subcuta | 1984 |
Therapy and monitoring of hypersiderosis in chronic renal insufficiency.
Topics: Aluminum; Anemia, Hypochromic; Blood; Blood Transfusion; Combined Modality Therapy; Deferoxamine; He | 1984 |
[Diagnosis and therapy of iron overload with desferrioxamine].
Topics: Blood Transfusion; Deferoxamine; Ferritins; Hemosiderosis; Humans; Iron; Liver; Transferrin | 1984 |
Deferoxamine (Desferal)-induced toxic retinal pigmentary degeneration and presumed optic neuropathy.
Topics: Aged; Blood Transfusion; Color Perception; Deferoxamine; Female; Hemosiderosis; Humans; Male; Middle | 1984 |
[Transfusion induced hypersiderosis in aplastic anemia--physiopathology and therapeutic aspects].
Topics: Anemia, Aplastic; Deferoxamine; Hemosiderosis; Humans; Infusions, Parenteral; Iron; Transfusion Reac | 1983 |
Pancreatic sonography in thalassemia major.
Topics: Adolescent; Adult; Blood Transfusion; Child; Deferoxamine; Hemosiderosis; Humans; Pancreatic Disease | 1983 |
Fish as models for hemosiderosis.
Topics: Animals; Biopsy; Deferoxamine; Disease Models, Animal; Fishes; Hemosiderin; Hemosiderosis; Iron; Iro | 1980 |
Current concepts in the overall management of thalassemia.
Topics: Biological Transport; Blood Transfusion; Chelating Agents; Deferoxamine; Erythrocyte Transfusion; Ex | 1980 |
Improved pituitary gonadotrophin response in adult transfusional haemosiderosis following desferrioxamine treatment.
Topics: Deferoxamine; Gonadotropins, Pituitary; Hemosiderosis; Humans; Male; Middle Aged; Pituitary Function | 1982 |
Hemosiderosis in a dialysis patient: treatment with hemofiltration and deferoxamine chelation therapy.
Topics: Aged; Blood; Deferoxamine; Drug Combinations; Female; Hemosiderosis; Humans; Nephrosclerosis; Renal | 1982 |
[Continuous subcutaneous desferrioxamine infusions in patients with hemosiderosis (author's transl)].
Topics: Adolescent; Adult; Anemia, Aplastic; Child; Child, Preschool; Deferoxamine; Hemosiderosis; Humans; I | 1982 |
Ferrioxamine excretion in iron-loaded man.
Topics: Adult; Ascorbic Acid; Deferoxamine; Dose-Response Relationship, Drug; Feces; Hemosiderosis; Humans; | 1982 |
[Long-term study in congenital refractory anemia and secondary siderosis].
Topics: Adolescent; Anemia, Aplastic; Deferoxamine; Dwarfism; Female; Hemosiderosis; Humans; Hypogonadism; H | 1982 |
Effect of subcutaneous deferoxamine and oral vitamin C on iron excretion in congenital hypoplastic anemia and refractory anemia associated with the 5q-syndrome.
Topics: Administration, Oral; Anemia, Aplastic; Ascorbic Acid; Blood Transfusion; Child; Chromosome Aberrati | 1982 |
Desferrioxamine in the management of dialysis hemosiderosis.
Topics: Deferoxamine; Hemosiderosis; Humans; Iron; Renal Dialysis; Transfusion Reaction | 1982 |
Treatment of hemodialysis hemosiderosis with desferrioxamine.
Topics: Deferoxamine; Hemosiderosis; Humans; Renal Dialysis | 1982 |
Chelation therapy for iron overload.
Topics: Animals; Chelating Agents; Deferoxamine; Hemochromatosis; Hemosiderosis; Humans; Rats; Thalassemia | 1980 |
Liposome-encapsulated desferrioxamine in experimental iron overload.
Topics: Animals; Deferoxamine; Erythrocytes; Female; Ferritins; Hemosiderosis; Hot Temperature; Iron; Liposo | 1981 |
Continuous high-dose intravenous desferrioxamine treatment for iron overload.
Topics: Aged; Anemia, Aplastic; Deferoxamine; Erythrocyte Transfusion; Hemosiderosis; Humans; Infusions, Par | 1981 |
Intravenous and subcutaneous desferrioxamine therapy in children with severe iron overload.
Topics: Adolescent; Anemia, Aplastic; Anemia, Sideroblastic; Child; Child, Preschool; Deferoxamine; Hemoside | 1981 |
[Treatment and prevention of chronic iron overload (author's transl)].
Topics: Bloodletting; Deferoxamine; Hematologic Diseases; Hemochromatosis; Hemosiderosis; Humans; Iron; Live | 1981 |
[Iron-overload in patients on maintenance hemodialysis: diagnostic criteria, indications and treatment by desferrioxamine (author's transl)].
Topics: Adult; Aged; Biopsy, Needle; Deferoxamine; Female; Ferritins; Hemochromatosis; Hemosiderosis; Hepati | 1981 |
[Deferoxamine B treatment of hemosiderosis in the anephric patient undergoing hemodialysis].
Topics: Adult; Deferoxamine; Hemosiderosis; Humans; Kidney Failure, Chronic; Male; Renal Dialysis | 1981 |
Depressed serum somatomedin activity in beta-thalassemia.
Topics: Adolescent; Adult; Child; Child, Preschool; Deferoxamine; Female; Growth Disorders; Hemosiderosis; H | 1980 |
Transfusion therapy: its role in the anemias.
Topics: Anemia; Blood Group Incompatibility; Blood Grouping and Crossmatching; Deferoxamine; Erythrocyte Tra | 1980 |
[Treatment of iron overload due to repeated transfusions with subcutaneous infusions of desferrioxamine (author's transl)].
Topics: Adolescent; Adult; Child; Child, Preschool; Deferoxamine; Female; Ferritins; Hemosiderosis; Humans; | 1980 |
Vitamin C and iron.
Topics: Administration, Oral; Adult; Animals; Ascorbic Acid; Ascorbic Acid Deficiency; Deferoxamine; Female; | 1981 |
Deferoxamine in thalassemia major.
Topics: beta-Thalassemia; Deferoxamine; Hemosiderosis; Humans | 1995 |
[Treatment of iron overload states with oral administration of the chelator agent, L1 (Deferiprone)].
Topics: Administration, Oral; Deferiprone; Deferoxamine; Hemosiderosis; Humans; Iron Chelating Agents; Pyrid | 1994 |
Autoantibodies in thalassaemia major: relationship with oral iron chelator L1.
Topics: Adolescent; Adult; Antibodies, Antinuclear; Autoimmune Diseases; Blood Transfusion; Child; Deferipro | 1993 |
Cardiac study by dobutamine stress echocardiography in thalassemic patients.
Topics: Adolescent; Adult; beta-Thalassemia; Chelation Therapy; Child; Combined Modality Therapy; Deferoxami | 1993 |
Liver iron stores in patients with secondary haemosiderosis under iron chelation therapy with deferoxamine or deferiprone.
Topics: Adult; Aged; Biophysical Phenomena; Biophysics; Child; Child, Preschool; Deferoxamine; Female; Ferri | 1995 |
Deferoxamine-induced platyspondyly in hypertransfused thalassemic patients.
Topics: Adult; beta-Thalassemia; Body Height; Deferoxamine; Female; Follow-Up Studies; Hemosiderosis; Humans | 1995 |
Improvement of erythropoiesis during treatment with deferiprone in a patient with myelofibrosis and transfusional hemosiderosis.
Topics: Adult; Deferoxamine; Erythropoiesis; Hemosiderosis; Humans; Male; Siderophores; Transfusion Reaction | 1996 |
Logarithmic quantitation model using serum ferritin to estimate iron overload in secondary haemochromatosis.
Topics: Adolescent; Anemia; Child; Child, Preschool; Deferoxamine; Erythrocyte Transfusion; Ferritins; Hemoc | 1996 |
Estimation of statistical moments for desferrioxamine and its iron and aluminum chelates: contribution to optimisation of therapy in uremic patients.
Topics: Aluminum; Antidotes; Chelating Agents; Data Interpretation, Statistical; Deferoxamine; Drug Administ | 1996 |
Kinetics of removal and reappearance of non-transferrin-bound plasma iron with deferoxamine therapy.
Topics: Adolescent; Adult; beta-Thalassemia; Body Fluid Compartments; Chelation Therapy; Child; Deferoxamine | 1996 |
A novel delivery system for continuous desferrioxamine infusion in transfusional iron overload.
Topics: Adolescent; Adult; Anemia, Sickle Cell; beta-Thalassemia; Deferoxamine; Drug Delivery Systems; Femal | 1996 |
The effect of iron chelation on haemopoiesis in MDS patients with transfusional iron overload.
Topics: Adolescent; Aged; Bone Marrow Diseases; Chromosome Aberrations; Deferoxamine; Erythropoietin; Female | 1996 |
[Comparative evaluation of two models of hemosiderosis for analysis of iron chelators].
Topics: Animals; Deferoxamine; Disease Models, Animal; Female; Hemosiderosis; Iron; Iron Chelating Agents; M | 1996 |
Ferritin-associated iron induces neutrophil dysfunction in hemosiderosis.
Topics: Adolescent; beta-Thalassemia; Blood Transfusion; Catalase; Chelating Agents; Child; Child, Preschool | 1999 |
Epidemiological situation and treatment of patients with thalassemia major in Germany: results of the German multicenter beta-thalassemia study.
Topics: Adolescent; Adult; beta-Thalassemia; Blood Transfusion; Chelating Agents; Child; Child, Preschool; D | 2000 |
Juvenile hemochromatosis associated with B-thalassemia treated by phlebotomy and recombinant human erythropoietin.
Topics: Adrenal Cortex Hormones; Adrenal Insufficiency; Adult; Arrhythmias, Cardiac; beta-Thalassemia; Chela | 2000 |
Desferrioxamine-chelatable iron (DCI), a component of serum non-transferrin-bound iron (NTBI) used for assessing iron chelation therapy.
Topics: Chelating Agents; Deferoxamine; Drug Monitoring; Hemosiderosis; Humans; Iron; Transfusion Reaction | 2000 |
Effect of dose, time, and ascorbate on iron excretion after subcutaneous desferrioxamine.
Topics: Administration, Oral; Adolescent; Adult; Anemia, Sideroblastic; Ascorbic Acid; Child; Deferoxamine; | 1977 |
Desferrioxamine and transfusional iron overload.
Topics: Adolescent; Child; Child, Preschool; Deferoxamine; Hemosiderosis; Humans; Transfusion Reaction | 1978 |
Subcutaneous desferrioxamine in homozygous beta-thalassaemia.
Topics: Adolescent; Adult; Age Factors; Child; Child, Preschool; Deferoxamine; Hemosiderosis; Homozygote; Hu | 1978 |
Improvement in iron status and liver function in patients with transfusional iron overload with long-term subcutaneous desferrioxamine.
Topics: Adolescent; Adult; Aged; Anemia, Aplastic; Anemia, Sideroblastic; Aspartate Aminotransferases; Child | 1979 |
Acute renal insufficiency occurring during intravenous desferrioxamine therapy.
Topics: Acute Kidney Injury; Adolescent; Deferoxamine; Hemosiderosis; Humans; Injections, Intravenous; Male; | 1979 |
[The effect of desferrioxamine on the treatment of transfusion hemosiderosis--with special reference to the method of its administration (authors' transl)].
Topics: Adult; Aged; Anemia, Aplastic; Deferoxamine; Female; Hemosiderosis; Humans; Iron; Male; Transfusion | 1977 |
Treatment of iron overload in adults with continuous parenteral desferrioxamine.
Topics: Adult; Aged; Ascorbic Acid; Biopsy, Needle; Deferoxamine; Female; Ferritins; Hemosiderosis; Humans; | 1977 |
Evaluation of continuous desferrioxamine administration in adults with transfusional hemosiderosis.
Topics: Adult; Anemia, Sideroblastic; Ascorbic Acid; Deferoxamine; Drug Administration Schedule; Female; Hem | 1977 |
Pharmacokinetics of the iron chelator desperrioxamine as affected by liposome encapsulation: potential in treatment of chronic hemosiderosis.
Topics: Animals; Capsules; Chronic Disease; Deferoxamine; Female; Hemosiderosis; Injections, Intravenous; Ir | 1978 |
Iron burden in sickle cell anemia.
Topics: Adolescent; Adult; Anemia, Sickle Cell; Body Burden; Child; Child, Preschool; Deferoxamine; Ferritin | 1978 |
[Further experiences with iron-chelating therapy (desferrioxamine and ascorbic acid) in siderochromatosis and Cooley's disease].
Topics: Adolescent; Adult; Aged; Ascorbic Acid; Deferoxamine; Drug Evaluation; Female; Hemochromatosis; Hemo | 1978 |
Chronic iron overload: new chelators and new strategies.
Topics: Anemia, Sideroblastic; Animals; Ascorbic Acid; Chelating Agents; Deferoxamine; Hemosiderosis; Humans | 1978 |
[Changes in urinary iron in thalassemia major in relation to the administration of desferrioxamine].
Topics: Child; Child, Preschool; Deferoxamine; Hemosiderosis; Humans; Infant; Iron; Thalassemia | 1978 |
[Idiopathic pulmonary hemosiderosis].
Topics: Child, Preschool; Chronic Disease; Cortisone; Deferoxamine; Female; Hemosiderosis; Humans; Immunosup | 1978 |
Hemosiderosis in a patient on regular hemodialysis: treatment by desferrioxamine.
Topics: Deferoxamine; Female; Hemosiderosis; Humans; Iron; Middle Aged; Renal Dialysis; Transfusion Reaction | 1976 |
[The value of nuclear magnetic resonance in the study of iron overload in thalassemia patients].
Topics: Adolescent; Adult; Alanine Transaminase; Cardiomyopathies; Child; Deferoxamine; Ferritins; Hemosider | 1991 |
Failure of deferoxamine to improve iron overload in chronic hemodialysis patients.
Topics: Deferoxamine; Dialysis Solutions; Hemosiderosis; Humans; Iron; Kidney Failure, Chronic; Long-Term Ca | 1990 |
Treatment of iron overload in children and adolescents on chronic haemodialysis.
Topics: Child; Child, Preschool; Deferoxamine; Female; Ferritins; Hemosiderosis; Humans; Male; Renal Dialysi | 1990 |
[A 2-year-old male patient with congenital sideroblastic anemia and long-term chelation therapy].
Topics: Anemia, Sideroblastic; Blood Transfusion; Bone Marrow; Child, Preschool; Combined Modality Therapy; | 1989 |
Infection with Yersinia enterocolitica in patients with iron overload.
Topics: Adult; Anemia, Sideroblastic; Blood Transfusion; Deferoxamine; Female; Hemosiderosis; Humans; Male; | 1986 |
Reappraisal of high-dose desferrioxamine therapy.
Topics: Deferoxamine; Hemosiderosis; Humans; Thalassemia; Transfusion Reaction | 1986 |
Improvement of anaemia with desferrioxamine in haemodialysis patients.
Topics: Adult; Aluminum; Anemia; Blood Transfusion; Deferoxamine; Female; Hematocrit; Hemosiderosis; Humans; | 1987 |
Diagnosis and treatment of iron overload in paediatric patients on chronic haemodialysis.
Topics: Adolescent; Adult; Alanine Transaminase; Child; Child, Preschool; Deferoxamine; Female; Ferritins; H | 1988 |
[Effect of continuous subcutaneous infusion of deferoxamine in a boy with congenital hypoplastic anemia].
Topics: Anemia, Aplastic; Child, Preschool; Deferoxamine; Drug Evaluation; Erythrocyte Transfusion; Hemoside | 1988 |
Yersinia enterocolitica septicaemia.
Topics: Adult; Deferoxamine; Hemosiderosis; Humans; Sepsis; Thalassemia; Yersinia enterocolitica; Yersinia I | 1988 |
Respective role of haemosiderosis and desferrioxamine therapy in the risk from infection of haemodialysed patients.
Topics: Bacterial Infections; Deferoxamine; Hemosiderosis; Humans; Renal Dialysis; Risk Factors | 1988 |
[Subcutaneous administration of deferoxamine in a patient with panmyelopathy and post-transfusion hemosiderosis].
Topics: Adult; Anemia, Aplastic; Deferoxamine; Hemosiderosis; Humans; Injections, Subcutaneous; Male; Transf | 1987 |
[Yersinia septicemia in children with thalassaemia major].
Topics: Child; Child, Preschool; Deferoxamine; Female; Hemosiderosis; Humans; Male; Risk Factors; Sepsis; Th | 1987 |
Iron overload, but not treatment with desferrioxamine favours the development of septicemia in patients on maintenance hemodialysis.
Topics: Aged; Bacterial Infections; Deferoxamine; Female; Hemosiderosis; Humans; Kidney Failure, Chronic; Ma | 1987 |
[Continuous subcutaneous deferoxamine infusions in thalassemia major. Improvement in glucose tolerance].
Topics: Adolescent; Adult; alpha-Amylases; Blood Glucose; Child; Child, Preschool; Deferoxamine; Diabetes Co | 1986 |
Iron overload and mobilization in long-term hemodialysis patients.
Topics: Adult; Bone Diseases; Child; Deferoxamine; Erythrocyte Transfusion; Female; Ferritins; Hemochromatos | 1987 |
Fatal Rhizopus infections in hemodialysis patients receiving deferoxamine.
Topics: Adult; Aged; Aluminum; Deferoxamine; Encephalitis; Female; Hemosiderosis; Humans; Male; Middle Aged; | 1987 |
Hemosiderosis in rodents and the effect of acetohydroxamic acid on urinary iron excretion.
Topics: Animals; Chelating Agents; Deferoxamine; Disease Models, Animal; Erythrocytes; Hemosiderosis; Hydrox | 1986 |
Deferoxamine-enhanced fecal losses of aluminum and iron in a patient undergoing continuous ambulatory peritoneal dialysis.
Topics: Adult; Aluminum; Deferoxamine; Feces; Female; Hemosiderosis; Humans; Iron; Iron Deficiencies; Osteom | 1987 |
Long-term efficacy of deferoxamine iron chelation therapy in adults with acquired transfusional iron overload.
Topics: Adult; Anemia; Blood Glucose; Deferoxamine; Glucose Tolerance Test; Hemosiderosis; Humans; Iron; Iro | 1985 |
[Continuous subcutaneous deferoxamine treatment in thalassemia major. Decrease of hemosiderosis and improvement of liver function].
Topics: Adolescent; Adult; Child; Child, Preschool; Deferoxamine; Hemosiderosis; Humans; Injections, Subcuta | 1985 |
[Desferal test in the diagnosis of hemosiderosis in patents with hemoglobinopathies].
Topics: Adolescent; Adult; Aged; Anemia, Sickle Cell; Child; Child, Preschool; Deferoxamine; Female; Hemoglo | 1971 |
Effect of phenylhydrazine-induced haemolysis on the urinary excretion of iron after desferrioxamine.
Topics: Anemia, Sideroblastic; Animals; Biopsy; Bone Marrow Examination; Deferoxamine; Feces; Guinea Pigs; H | 1967 |
[Effect of desferrioxamine B on tissue sections of hemosiderosis of the kidney].
Topics: Adrenal Glands; Adult; Blood Transfusion; Buffers; Cortisone; Deferoxamine; Fats; Hemoglobinuria, Pa | 1966 |
[A case of Diamond-Blackfan anemia: Experiences of 10-year follow-up study].
Topics: Adolescent; Anemia, Aplastic; Biopsy; Blood Transfusion; Child; Child, Preschool; Deferoxamine; Eryt | 1974 |
[Treatment of hematocornea with desferrioxamine B by intralamellar injection].
Topics: Adolescent; Aqueous Humor; Corneal Opacity; Deferoxamine; Female; Hemoglobins; Hemosiderosis; Humans | 1971 |
[Desferal treatment of hemosiderosis in hemoglobinopathies (based on records from Kuveit)].
Topics: Adolescent; Adult; Child; Child, Preschool; Deferoxamine; Female; Georgia (Republic); Hemoglobinopat | 1971 |
Long-term administration of desferrioxamine in thalassaemia major.
Topics: Adolescent; Adult; Aspartate Aminotransferases; Bilirubin; Blood Protein Electrophoresis; Blood Tran | 1974 |
[Treatment of primary idiopathic hemochromatosis and secondary hemosiderosis].
Topics: Bloodletting; Deferoxamine; Hemochromatosis; Hemosiderosis; Humans; Iron; Male; Prognosis | 1974 |
Combined long-term treatment of hemosiderosis with desferioxamine and DTPA in homozygous beta-thalassemia.
Topics: Adolescent; Adult; Blood Transfusion; Child; Deferoxamine; Drug Therapy, Combination; Erythrocytes; | 1974 |
[Treatment of hypersiderosis with Desferal].
Topics: Deferoxamine; Hemosiderosis; Humans; Iron; Transfusion Reaction | 1972 |
[Clinical contribution to the therapy of siderochromatosis].
Topics: Adult; Blood Transfusion; Bloodletting; Deferoxamine; Diet Therapy; Edetic Acid; Female; Hemosideros | 1966 |
[Nosological classification and new therapeutic trends in idiopathic pulmonary hemosiderosis].
Topics: Adrenal Cortex Hormones; Azathioprine; Blood Protein Electrophoresis; Child, Preschool; Deferoxamine | 1966 |
Diagnosis of iron storage disease with desferrioxamine (Desferal test).
Topics: Anemia, Macrocytic; Anemia, Sickle Cell; Deferoxamine; Female; Hemochromatosis; Hemosiderosis; Human | 1964 |
The effective use of oxymetholone in the therapy of thalassaemia with anaemia.
Topics: Adult; Child; Deferoxamine; Hemosiderosis; Humans; Oxymetholone; Thalassemia | 1972 |
EXcretion and distribution of iron during chronic deferoxamine therapy.
Topics: Anemia, Aplastic; Bone Marrow; Bone Marrow Examination; Child; Chromium Isotopes; Deferoxamine; Foli | 1971 |
Studies on iron metabolism with desferrioxamine in man. Experimental and clinical studies.
Topics: Adult; Aged; Allopurinol; Anemia, Hypochromic; Blood Transfusion; Deferoxamine; Diet; Erythrocytes; | 1969 |
Management of thalassemia: a comparative program.
Topics: Adolescent; Asian People; Blood Transfusion; Body Height; Body Weight; Child; Child, Preschool; Defe | 1969 |
[The deferoxamine test].
Topics: Deferoxamine; Hematologic Diseases; Hemosiderosis; Humans; Injections, Intramuscular; Iron; Uremia | 1970 |
[Desferal therapy of hemosiderosis in patients with hemoglobinopathies].
Topics: Child; Child, Preschool; Deferoxamine; Female; Hemoglobinopathies; Hemosiderosis; Humans | 1970 |
Storage iron and desferrioxamine.
Topics: Adolescent; Adult; Age Factors; Aged; Anemia, Hemolytic; Anemia, Hypochromic; Anemia, Macrocytic; De | 1970 |
[Hemosiderosis and idiopathic hemochromatosis].
Topics: Bloodletting; Deferoxamine; Diagnosis, Differential; Hemochromatosis; Hemosiderosis; Humans; Iron; I | 1967 |
[Massive renal hemosiderosis in Marchiafava anemia and the possibility of an in-vitro desferrization through desferriofamine B].
Topics: Adult; Deferoxamine; Erythrocyte Count; Hemoglobinuria; Hemosiderosis; Humans; Kidney Diseases; Kidn | 1967 |
[Exchange transfusion and splenectomy for hyperbilirubinemia caused by hereditary spherocytosis in the neonatal period].
Topics: Deferoxamine; Exchange Transfusion, Whole Blood; Female; Hemosiderosis; Humans; Hyperbilirubinemia, | 1967 |
[Deferoxamine-B test. Evaluation of the organism's iron content by loading with a ferriuretic chelate].
Topics: Adolescent; Adult; Age Factors; Aged; Bone Marrow; Child; Deferoxamine; Female; Hemochromatosis; Hem | 1967 |
[Results obtained in the treatment of post-transfusional hemosiderosis with desferrioxamine ina case of hypoplastic congenital anemia of the Joseph-Blackfan-Diamon type].
Topics: Blood Transfusion; Child, Preschool; Deferoxamine; Female; Hemosiderosis; Humans | 1967 |
[On the usefulness of iron kinetics studied with Fe59 in the differential diagnosis of idiopathic siderochromatosis and that secondary to liver diseases].
Topics: Adult; Deferoxamine; Hemochromatosis; Hemosiderosis; Humans; Iron; Iron Isotopes; Liver Diseases; Mi | 1967 |
[Current status of treatments with desferrioxamine B in post-transfusion hypersiderosis in children].
Topics: Adolescent; Anemia, Aplastic; Anemia, Hemolytic; Child; Child, Preschool; Deferoxamine; Female; Hemo | 1967 |
Congenital erythroblastic hypoplasia. Treatment of transfusion hemosiderosis with desferrioxamine B.
Topics: Adolescent; Adult; Anemia, Aplastic; Child; Child, Preschool; Deferoxamine; Hemosiderosis; Humans; I | 1968 |
"Desferrioxamine-B" test for detecting excess iron storage in man.
Topics: Adult; Aged; Deferoxamine; Hemosiderosis; Humans; Iron; Middle Aged | 1968 |
[Damage to the liver parenchyma induced by desferrioxamine B therapy].
Topics: Chemical and Drug Induced Liver Injury; Deferoxamine; Hemosiderosis; Humans; Liver | 1968 |
[Use of desferal and some data on hemosiderosis in hypo- and aplastic anemias].
Topics: Acute Disease; Adolescent; Adult; Anemia, Aplastic; Chronic Disease; Deferoxamine; Female; Hemochrom | 1968 |
Effect of desferrioxamine B. A new iron eliminating agent, on cases of secondary haemosiderosis in children.
Topics: Child; Child, Preschool; Deferoxamine; Female; Hemosiderosis; Humans; Iron; Liver; Male; Siderosis; | 1969 |
[Microchemical determination of urinary iron in infants and children].
Topics: Adolescent; Age Factors; Anemia, Hypochromic; Child; Child, Preschool; Deferoxamine; Hemosiderosis; | 1969 |
[Use of desferrioxamine B in normal subjects and in patients with increased iron storage].
Topics: Adolescent; Adult; Child; Deferoxamine; Hemochromatosis; Hemosiderosis; Humans; In Vitro Techniques | 1965 |
Transfusion hemosiderosis. Report of a case treated with desferrioxamine-B.
Topics: Adult; Anemia, Sideroblastic; Deferoxamine; Hemosiderosis; Humans; Male; Transfusion Reaction | 1965 |
[The use of desferrioxamine in iron poisoning and hemosiderosis].
Topics: Arthritis, Rheumatoid; Child, Preschool; Deferoxamine; Hematopoietic System; Hemosiderosis; Humans; | 1965 |
[Demonstration of increased iron storage in the organism with desferrioxamine (desferal test)].
Topics: Deferoxamine; Hemochromatosis; Hemosiderosis; Humans; Iron; Jaundice; Liver Diseases; Porphyrias | 1965 |
[Clinical and metabolic research on treatment with desferrioxamine B in various hemosiderotic erythrocyte diseases].
Topics: Adolescent; Adult; Aged; Anemia; Child; Child, Preschool; Deferoxamine; Female; Hemosiderosis; Human | 1965 |
Iron chelation in acute iron poisoning and chronic hypersiderosis.
Topics: Adolescent; Chemical and Drug Induced Liver Injury; Child; Child, Preschool; Deferoxamine; Female; H | 1965 |
[A new iron chelating agent: desferrioxamine B (Desferal). Clinico-pharmacological observations. Cases].
Topics: Adolescent; Adult; Aged; Anemia, Macrocytic; Deferoxamine; Female; Hemosiderosis; Humans; Male; Midd | 1965 |
[Specific treatment of excessive iron deposition in the tissues].
Topics: Administration, Oral; Bloodletting; Chelating Agents; Connective Tissue; Deferoxamine; Hemochromatos | 1965 |
Differential ferrioxamine test in idiopathic haemochromatosis and transfusional haemosiderosis.
Topics: Adolescent; Adult; Aged; Anemia, Hemolytic; Biopsy; Blood Chemical Analysis; Bloodletting; Deferoxam | 1966 |
[Effects of desferrioxamine on iron elimination in children after multiple transfusions].
Topics: Blood Transfusion; Child; Deferoxamine; Hemosiderosis; Humans; Iron; Thalassemia | 1966 |
Sideruria following a single dose of desferrioxamine-B as a diagnostic test in iron overload.
Topics: Adult; Anemia, Hemolytic; Blood; Bone Marrow; Deferoxamine; Female; Hemochromatosis; Hemosiderosis; | 1966 |
Tightness of the skin over the feet and lower limbs associated with haemosiderosis.
Topics: Deferoxamine; Foot; Hemosiderosis; Humans; Leg; Male; Middle Aged; Skin Manifestations | 1966 |
Urinary excretion of iron.
Topics: Adolescent; Adult; Aged; Anemia, Hypochromic; Animals; Child; Deferoxamine; Female; Hemoglobinuria; | 1966 |
Urinary iron excretion in patients with prosthetic heart valves.
Topics: Anemia, Hemolytic; Blood Transfusion; Chromium Isotopes; Deferoxamine; Erythrocytes; Heart Valve Pro | 1966 |
Transferrin behaviour in haemochromatosis.
Topics: Deferoxamine; Hemochromatosis; Hemosiderosis; Hepatitis A; Humans; Iron; Liver; Liver Cirrhosis; Mid | 1966 |
[Respective variations of sideremia and sideruria in cirrhotic patients following the desferrioxamine B test].
Topics: Deferoxamine; Hemosiderosis; Humans; Iron; Liver Cirrhosis; Siderosis | 1966 |
[Desferrioxamine-B in the diagnosis of hemosiderotic states and in the therapy of thalassemia. Apropos of 2 cases].
Topics: Child; Child, Preschool; Deferoxamine; Hemosiderosis; Humans; Iron; Male; Thalassemia | 1966 |
The treatment of hemosiderosis in thalassaemia major with desferrioxamine-B.
Topics: Adolescent; Anemia, Sickle Cell; Biopsy; Child; Deferoxamine; Female; Hemochromatosis; Hemosiderosis | 1966 |