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deferoxamine and Hemoglobinuria, Paroxysmal

deferoxamine has been researched along with Hemoglobinuria, Paroxysmal in 5 studies

Deferoxamine: Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
desferrioxamine B : An acyclic desferrioxamine that is butanedioic acid in which one of the carboxy groups undergoes formal condensation with the primary amino group of N-(5-aminopentyl)-N-hydroxyacetamide and the second carboxy group undergoes formal condensation with the hydroxyamino group of N(1)-(5-aminopentyl)-N(1)-hydroxy-N(4)-[5-(hydroxyamino)pentyl]butanediamide. It is a siderophore native to Streptomyces pilosus biosynthesised by the DesABCD enzyme cluster as a high affinity Fe(III) chelator.

Hemoglobinuria, Paroxysmal: A condition characterized by the recurrence of HEMOGLOBINURIA caused by intravascular HEMOLYSIS. In cases occurring upon cold exposure (paroxysmal cold hemoglobinuria), usually after infections, there is a circulating antibody which is also a cold hemolysin. In cases occurring during or after sleep (paroxysmal nocturnal hemoglobinuria), the clonal hematopoietic stem cells exhibit a global deficiency of cell membrane proteins.

Research Excerpts

ExcerptRelevanceReference
"To report a case of acute bilateral central serous retinopathy associated with deferoxamine therapy in the context of paroxysmal nocturnal hemoglobinuria."7.83Bilateral central serous retinopathy in a patient with paroxysmal nocturnal hemoglobinuria treated with deferoxamine. ( Giasin, O; Kaneshyogan, H; Makrygiannis, G; Sian, IS; Vahdani, K, 2016)
"To report a case of acute bilateral central serous retinopathy associated with deferoxamine therapy in the context of paroxysmal nocturnal hemoglobinuria."3.83Bilateral central serous retinopathy in a patient with paroxysmal nocturnal hemoglobinuria treated with deferoxamine. ( Giasin, O; Kaneshyogan, H; Makrygiannis, G; Sian, IS; Vahdani, K, 2016)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19903 (60.00)18.7374
1990's0 (0.00)18.2507
2000's1 (20.00)29.6817
2010's1 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Vahdani, K1
Makrygiannis, G1
Kaneshyogan, H1
Sian, IS1
Giasin, O1
Nakakuma, H1
Mey, U1
Althoff, H1
Tejero Lamarca, J1
Yangüela Terroba, J1
Diáz-Flores, L1

Reviews

2 reviews available for deferoxamine and Hemoglobinuria, Paroxysmal

ArticleYear
[Attractiveness of paroxysmal nocturnal hemoglobinuria for study].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2008, Volume: 49, Issue:10

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Anticoagulants; Deferoxamine; Haptoglobin

2008
[Foundations of the diagnosis and therapy of hemolytic anemias].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1978, May-01, Volume: 33, Issue:9

    Topics: Agglutinins; Anemia, Hemolytic; Antigens; Autoimmune Diseases; Blood Protein Disorders; Blood Transf

1978

Other Studies

3 other studies available for deferoxamine and Hemoglobinuria, Paroxysmal

ArticleYear
Bilateral central serous retinopathy in a patient with paroxysmal nocturnal hemoglobinuria treated with deferoxamine.
    European journal of ophthalmology, 2016, Nov-04, Volume: 26, Issue:6

    Topics: Central Serous Chorioretinopathy; Deferoxamine; Fluorescein Angiography; Fundus Oculi; Hemoglobinuri

2016
[Effect of desferrioxamine B on tissue sections of hemosiderosis of the kidney].
    Arzneimittel-Forschung, 1966, Volume: 16, Issue:6

    Topics: Adrenal Glands; Adult; Blood Transfusion; Buffers; Cortisone; Deferoxamine; Fats; Hemoglobinuria, Pa

1966
[Nocturanl paroxysmal hemoglobinuria. II. Renal insufficiency in the course of the same (clinical, histological and ultramicroscopic study of the renal pathology and of its development after desferrioxamine therapy)].
    Revista clinica espanola, 1973, Feb-28, Volume: 128, Issue:4

    Topics: Acute Kidney Injury; Biopsy; Deferoxamine; Female; Hemoglobinuria, Paroxysmal; Humans; Injections, I

1973