deferoxamine has been researched along with Hemoglobinopathies in 12 studies
Deferoxamine: Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
desferrioxamine B : An acyclic desferrioxamine that is butanedioic acid in which one of the carboxy groups undergoes formal condensation with the primary amino group of N-(5-aminopentyl)-N-hydroxyacetamide and the second carboxy group undergoes formal condensation with the hydroxyamino group of N(1)-(5-aminopentyl)-N(1)-hydroxy-N(4)-[5-(hydroxyamino)pentyl]butanediamide. It is a siderophore native to Streptomyces pilosus biosynthesised by the DesABCD enzyme cluster as a high affinity Fe(III) chelator.
Hemoglobinopathies: A group of inherited disorders characterized by structural alterations within the hemoglobin molecule.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (41.67) | 18.7374 |
| 1990's | 5 (41.67) | 18.2507 |
| 2000's | 1 (8.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (8.33) | 2.80 |
| Authors | Studies |
|---|---|
| Borella, E | 1 |
| Oosterholt, S | 1 |
| Magni, P | 1 |
| Della Pasqua, O | 1 |
| Yap, J | 1 |
| O'Connor, C | 1 |
| Kirby, M | 1 |
| Guindi, M | 1 |
| Roberts, EA | 1 |
| RAY, RN | 1 |
| CHATTERJEA, JB | 1 |
| GHOSH, SK | 1 |
| Atamna, H | 1 |
| Ginsburg, H | 1 |
| Torcharus, K | 1 |
| Withayathawornwong, W | 1 |
| Sriphaisal, T | 1 |
| Krutvacho, T | 1 |
| Arnutti, P | 1 |
| Suwanasophorn, C | 1 |
| Chandler, ND | 1 |
| Parisi, MT | 1 |
| Styles, LA | 1 |
| Vichinsky, EP | 1 |
| Amendola, G | 1 |
| Garvin, J | 1 |
| Piomelli, S | 1 |
| Khutsishvili, GE | 3 |
| Orlova, LD | 1 |
| Iusuf, AM | 1 |
| Mainzer, K | 1 |
1 trial available for deferoxamine and Hemoglobinopathies
| Article | Year |
|---|---|
High transfusion in children with beta-thalassemia/Hb E: clinical and laboratory assessment of 18 cases.
Topics: Adolescent; beta-Thalassemia; Blood Transfusion; Child; Child, Preschool; Deferoxamine; Female; Ferr | 1993 |
11 other studies available for deferoxamine and Hemoglobinopathies
| Article | Year |
|---|---|
Characterisation of individual ferritin response in patients receiving chelation therapy.
Topics: Benzoates; Chelation Therapy; Deferasirox; Deferiprone; Deferoxamine; Ferritins; Hemoglobinopathies; | 2022 |
Sequential antiviral and iron chelation treatment in a teenage boy with congenital anemia, chronic hepatitis C, and secondary hemosiderosis.
Topics: Adolescent; Anemia; Antiviral Agents; Chelation Therapy; Deferoxamine; Ferritins; Hemoglobinopathies | 2009 |
DESFERRIOXAMINE IN HB-E-THALASSAEMIA DISEASE.
Topics: Chelating Agents; Deferoxamine; Hemoglobinopathies; Hemoglobins; Hemoglobins, Abnormal; Humans; Hydr | 1963 |
Heme degradation in the presence of glutathione. A proposed mechanism to account for the high levels of non-heme iron found in the membranes of hemoglobinopathic red blood cells.
Topics: Deferoxamine; Erythrocyte Membrane; Glutathione; Heme; Hemoglobinopathies; Humans; Hydrogen Peroxide | 1995 |
Radiological case of the month. Yersinia enterocolitica masquerading as appendicitis.
Topics: Abscess; Appendicitis; beta-Thalassemia; Biopsy; Child; Deferoxamine; Diagnosis, Differential; Hemog | 1994 |
Ototoxicity in hemoglobinopathy patients chelated with desferrioxamine.
Topics: Adolescent; Adult; Audiometry; Auditory Threshold; Chelation Therapy; Child; Child, Preschool; Defer | 1996 |
Cystic fibrosis in a black child with hemoglobin S-D disease.
Topics: Black People; Child; Cystic Fibrosis; Deferoxamine; Female; Hemochromatosis; Hemoglobinopathies; Hem | 1990 |
[Desferal test in the diagnosis of hemosiderosis in patents with hemoglobinopathies].
Topics: Adolescent; Adult; Aged; Anemia, Sickle Cell; Child; Child, Preschool; Deferoxamine; Female; Hemoglo | 1971 |
[Desferal treatment of hemosiderosis in hemoglobinopathies (based on records from Kuveit)].
Topics: Adolescent; Adult; Child; Child, Preschool; Deferoxamine; Female; Georgia (Republic); Hemoglobinopat | 1971 |
[Desferal therapy of hemosiderosis in patients with hemoglobinopathies].
Topics: Child; Child, Preschool; Deferoxamine; Female; Hemoglobinopathies; Hemosiderosis; Humans | 1970 |
[Significance of disorders of hemoglobin synthesis for the clinical practice].
Topics: Anemia, Macrocytic; Anemia, Sickle Cell; Deferoxamine; Erythrocyte Aging; Erythropoiesis; Hematologi | 1967 |