deferoxamine has been researched along with Helicobacter Infections in 3 studies
Deferoxamine: Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
desferrioxamine B : An acyclic desferrioxamine that is butanedioic acid in which one of the carboxy groups undergoes formal condensation with the primary amino group of N-(5-aminopentyl)-N-hydroxyacetamide and the second carboxy group undergoes formal condensation with the hydroxyamino group of N(1)-(5-aminopentyl)-N(1)-hydroxy-N(4)-[5-(hydroxyamino)pentyl]butanediamide. It is a siderophore native to Streptomyces pilosus biosynthesised by the DesABCD enzyme cluster as a high affinity Fe(III) chelator.
Helicobacter Infections: Infections with organisms of the genus HELICOBACTER, particularly, in humans, HELICOBACTER PYLORI. The clinical manifestations are focused in the stomach, usually the gastric mucosa and antrum, and the upper duodenum. This infection plays a major role in the pathogenesis of type B gastritis and peptic ulcer disease.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To evaluate the efficacy of bovine lactoferrin (BLf), recombinant human lactoferrin (rHLf) and desferrioxamine against Helicobacter pylori in vitro and in mice and also to determine whether BLf or rHLf alter gastric inflammation." | 7.75 | Lactoferrin and desferrioxamine are ineffective in the treatment of Helicobacter pylori infection and may enhance H. pylori growth and gastric inflammation in mice. ( Butler, RN; Campbell, MA; Couper, RT; Huynh, HQ; Lawrence, A; Tran, CD, 2009) |
| "To evaluate the efficacy of bovine lactoferrin (BLf), recombinant human lactoferrin (rHLf) and desferrioxamine against Helicobacter pylori in vitro and in mice and also to determine whether BLf or rHLf alter gastric inflammation." | 3.75 | Lactoferrin and desferrioxamine are ineffective in the treatment of Helicobacter pylori infection and may enhance H. pylori growth and gastric inflammation in mice. ( Butler, RN; Campbell, MA; Couper, RT; Huynh, HQ; Lawrence, A; Tran, CD, 2009) |
| " Pretreatment with extracellular GSH caused a right shift of the dose-response curve for NH2Cl, whereas pretreatment with diethyl maleate (a depletor of cellular GSH) rendered cells less resistant to NH2Cl." | 1.30 | Monochloramine-induced cytolysis to cultured rat gastric mucosal cells: role of glutathione and iron in protection and injury. ( Hiraishi, H; Ishida, M; Shimada, T; Terano, A; Yajima, N; Yamaguchi, N, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Huynh, HQ | 1 |
| Campbell, MA | 1 |
| Couper, RT | 1 |
| Tran, CD | 1 |
| Lawrence, A | 1 |
| Butler, RN | 1 |
| Dial, EJ | 1 |
| Hall, LR | 1 |
| Serna, H | 1 |
| Romero, JJ | 1 |
| Fox, JG | 1 |
| Lichtenberger, LM | 1 |
| Yajima, N | 1 |
| Hiraishi, H | 1 |
| Yamaguchi, N | 1 |
| Ishida, M | 1 |
| Shimada, T | 1 |
| Terano, A | 1 |
3 other studies available for deferoxamine and Helicobacter Infections
| Article | Year |
|---|---|
Lactoferrin and desferrioxamine are ineffective in the treatment of Helicobacter pylori infection and may enhance H. pylori growth and gastric inflammation in mice.
Topics: Animals; Anti-Bacterial Agents; Deferoxamine; Female; Gastric Mucosa; Helicobacter Infections; Helic | 2009 |
Antibiotic properties of bovine lactoferrin on Helicobacter pylori.
Topics: Animals; Anti-Bacterial Agents; Cattle; Deferoxamine; Dose-Response Relationship, Drug; Enzyme-Linke | 1998 |
Monochloramine-induced cytolysis to cultured rat gastric mucosal cells: role of glutathione and iron in protection and injury.
Topics: Animals; Biological Transport; Chelating Agents; Chloramines; Chromium Radioisotopes; Deferoxamine; | 1999 |