Page last updated: 2024-10-25

deferoxamine and Heavy Metal Poisoning

deferoxamine has been researched along with Heavy Metal Poisoning in 11 studies

Deferoxamine: Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
desferrioxamine B : An acyclic desferrioxamine that is butanedioic acid in which one of the carboxy groups undergoes formal condensation with the primary amino group of N-(5-aminopentyl)-N-hydroxyacetamide and the second carboxy group undergoes formal condensation with the hydroxyamino group of N(1)-(5-aminopentyl)-N(1)-hydroxy-N(4)-[5-(hydroxyamino)pentyl]butanediamide. It is a siderophore native to Streptomyces pilosus biosynthesised by the DesABCD enzyme cluster as a high affinity Fe(III) chelator.

Heavy Metal Poisoning: Poisoning that results from chronic or acute ingestion, injection, inhalation, or skin absorption of HEAVY METALS. Acute and chronic exposures can cause ANEMIA; KIDNEY and LIVER damage; PULMONARY EDEMA; MEMORY LOSS and behavioral changes; bone deformities in children; and MISCARRIAGE or PREMATURE LABOR in pregnant women.

Research Excerpts

ExcerptRelevanceReference
"Acute iron poisoning is a common and potentially serious problem in the pediatric population."1.39Successful treatment of severe iron intoxication with gastrointestinal decontamination, deferoxamine, and hemodialysis. ( Balwani, MR; Ghuge, PP; Gumber, MR; Kute, VB; Patel, HV; Shah, PR; Trivedi, HL; Vanikar, AV, 2013)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19908 (72.73)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (27.27)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gumber, MR1
Kute, VB1
Shah, PR1
Vanikar, AV1
Patel, HV1
Balwani, MR1
Ghuge, PP1
Trivedi, HL1
Fernández, S1
Castro, P1
Nogué, S1
Nicolás, JM1
Aaseth, J1
Skaug, MA1
Cao, Y1
Andersen, O1
SHAPIRO, N1
BARBEZAT, GO1
PITTMAN, AK2
MOESCHLIN, S1
SCHNIDER, U1
DUGDALE, AE1
POWELL, LW1
MCENERY, JT1
MACK, RB1
BURLEY, DM1
FIELDING, J1
CHAVANNE, H1
DEMILLIERE, B1

Reviews

1 review available for deferoxamine and Heavy Metal Poisoning

ArticleYear
Chelation in metal intoxication--Principles and paradigms.
    Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS), 2015, Volume: 31

    Topics: Administration, Oral; Antidotes; Benzoates; Chelating Agents; Deferasirox; Deferiprone; Deferoxamine

2015

Other Studies

10 other studies available for deferoxamine and Heavy Metal Poisoning

ArticleYear
Successful treatment of severe iron intoxication with gastrointestinal decontamination, deferoxamine, and hemodialysis.
    Renal failure, 2013, Volume: 35, Issue:5

    Topics: Adolescent; Deferoxamine; Female; Gastric Lavage; Heavy Metal Poisoning; Humans; Iron; Poisoning; Re

2013
Acute iron intoxication: change in urine color during chelation therapy with deferoxamine.
    Intensive care medicine, 2014, Volume: 40, Issue:1

    Topics: Chelation Therapy; Color; Deferoxamine; Female; Ferrous Compounds; Heavy Metal Poisoning; Humans; Ir

2014
A CASE OF ACUTE IRON POISONING TREATED WITH DESFERRIOXAMINE B.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1964, Jul-04, Volume: 38

    Topics: Chelating Agents; Child; Deferoxamine; Drug Therapy; Heavy Metal Poisoning; Humans; Hydroxamic Acids

1964
DESFERRIOXAMINE AND ACUTE IRON POISONING.
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1964, Volume: 1587

    Topics: Deferoxamine; Heavy Metal Poisoning; Injections, Intramuscular; Iron; Iron Metabolism Disorders; Met

1964
DESFERRIOXAMINE AND ACUTE IRON POISONING.
    British medical journal, 1964, Oct-31, Volume: 2, Issue:5417

    Topics: Deferoxamine; Heavy Metal Poisoning; Iron; Iron Metabolism Disorders; Metals, Heavy; Poisoning; Toxi

1964
TREATMENT OF PRIMARY AND SECONDARY HEMOCHROMATOSIS AND ACUTE IRON POISONING WITH A NEW POTENT IRON ELIMINATING AGENT (DESFERRIOXAMINE B-DFOM).
    Nederlands tijdschrift voor geneeskunde, 1964, Aug-22, Volume: 108

    Topics: Anemia; Anemia, Aplastic; Anemia, Hemolytic; Anemia, Macrocytic; Deferoxamine; Guinea Pigs; Heavy Me

1964
ACUTE IRON POISONING: ITS EFFECTS AND TREATMENT.
    The Medical journal of Australia, 1964, Oct-19, Volume: 2

    Topics: Chelating Agents; Deferoxamine; Drug Therapy; Drug-Related Side Effects and Adverse Reactions; Edeti

1964
USE OF DESFERRIOXAMINE IN A CASE OF ACUTE FERROUS SULFATE POISONING.
    IMJ. Illinois medical journal, 1964, Volume: 126

    Topics: Child; Deferoxamine; Drug Therapy; Ferrous Compounds; Heavy Metal Poisoning; Metals, Heavy; Poisonin

1964
MANAGEMENT OF ACUTE IRON POISONING.
    British medical journal, 1965, Apr-10, Volume: 1, Issue:5440

    Topics: Deferoxamine; Drug Therapy; Heavy Metal Poisoning; Iron; Iron Metabolism Disorders; Metals, Heavy; P

1965
[TRIAL OF A NEW IRON CHELATOR, DESFERRIOXAMINE B, IN A CASE OF OCULAR SIDEROSIS].
    Bulletin des societes d'ophtalmologie de France, 1964, Volume: 64

    Topics: Chelating Agents; Deferoxamine; Eye Diseases; Heavy Metal Poisoning; Humans; Iron; Iron Metabolism D

1964