deferoxamine has been researched along with Headache in 1 studies
Deferoxamine: Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
desferrioxamine B : An acyclic desferrioxamine that is butanedioic acid in which one of the carboxy groups undergoes formal condensation with the primary amino group of N-(5-aminopentyl)-N-hydroxyacetamide and the second carboxy group undergoes formal condensation with the hydroxyamino group of N(1)-(5-aminopentyl)-N(1)-hydroxy-N(4)-[5-(hydroxyamino)pentyl]butanediamide. It is a siderophore native to Streptomyces pilosus biosynthesised by the DesABCD enzyme cluster as a high affinity Fe(III) chelator.
Headache: The symptom of PAIN in the cranial region. It may be an isolated benign occurrence or manifestation of a wide variety of HEADACHE DISORDERS.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Vichinsky, E | 1 |
| Onyekwere, O | 1 |
| Porter, J | 1 |
| Swerdlow, P | 1 |
| Eckman, J | 1 |
| Lane, P | 1 |
| Files, B | 1 |
| Hassell, K | 1 |
| Kelly, P | 1 |
| Wilson, F | 1 |
| Bernaudin, F | 1 |
| Forni, GL | 1 |
| Okpala, I | 1 |
| Ressayre-Djaffer, C | 1 |
| Alberti, D | 1 |
| Holland, J | 1 |
| Marks, P | 1 |
| Fung, E | 1 |
| Fischer, R | 1 |
| Mueller, BU | 1 |
| Coates, T | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Randomized, Open Label, Phase II Study on Safety and Efficacy of Long Term Treatment of ICL670 Relative to Deferoxamine in Sickle Cell Disease Patients With Transfusional Hemosiderosis[NCT00067080] | Phase 2 | 195 participants (Actual) | Interventional | 2003-05-31 | Completed | ||
| Clinical Importance of Treating Iron Overload in Sickle Cell Disease[NCT00981370] | Phase 3 | 1 participants (Actual) | Interventional | 2009-04-30 | Terminated (stopped due to 1 consented patient never started on study drug, lost to follow up) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for deferoxamine and Headache
| Article | Year |
|---|---|
A randomised comparison of deferasirox versus deferoxamine for the treatment of transfusional iron overload in sickle cell disease.
Topics: Administration, Oral; Adolescent; Adult; Alanine Transaminase; Anemia, Sickle Cell; Benzoates; Blood | 2007 |
A randomised comparison of deferasirox versus deferoxamine for the treatment of transfusional iron overload in sickle cell disease.
Topics: Administration, Oral; Adolescent; Adult; Alanine Transaminase; Anemia, Sickle Cell; Benzoates; Blood | 2007 |
A randomised comparison of deferasirox versus deferoxamine for the treatment of transfusional iron overload in sickle cell disease.
Topics: Administration, Oral; Adolescent; Adult; Alanine Transaminase; Anemia, Sickle Cell; Benzoates; Blood | 2007 |
A randomised comparison of deferasirox versus deferoxamine for the treatment of transfusional iron overload in sickle cell disease.
Topics: Administration, Oral; Adolescent; Adult; Alanine Transaminase; Anemia, Sickle Cell; Benzoates; Blood | 2007 |