Page last updated: 2024-10-25

deferoxamine and HIV Coinfection

deferoxamine has been researched along with HIV Coinfection in 6 studies

Deferoxamine: Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
desferrioxamine B : An acyclic desferrioxamine that is butanedioic acid in which one of the carboxy groups undergoes formal condensation with the primary amino group of N-(5-aminopentyl)-N-hydroxyacetamide and the second carboxy group undergoes formal condensation with the hydroxyamino group of N(1)-(5-aminopentyl)-N(1)-hydroxy-N(4)-[5-(hydroxyamino)pentyl]butanediamide. It is a siderophore native to Streptomyces pilosus biosynthesised by the DesABCD enzyme cluster as a high affinity Fe(III) chelator.

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (66.67)18.2507
2000's2 (33.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Borgna-Pignatti, C1
Rugolotto, S1
De Stefano, P1
Zhao, H1
Cappellini, MD1
Del Vecchio, GC1
Romeo, MA1
Forni, GL1
Gamberini, MR1
Ghilardi, R1
Piga, A1
Cnaan, A1
Costagliola, DG1
de Montalembert, M2
Lefrère, JJ1
Briand, C1
Rebulla, P2
Baruchel, S1
Dessi, C2
Fondu, P1
Karagiorga, M2
Perrimond, H1
Boelaert, JR1
Weinberg, GA1
Weinberg, ED1
Salhi, Y1
Costagliola, D1
Lena-Russo, D1
Girot, R1
Prati, D1
Davies, SC1
Wonke, B1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Iron-mediated Vascular Disease in Sickle Cell Disease.[NCT01239901]150 participants (Actual)Observational2009-12-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for deferoxamine and HIV Coinfection

ArticleYear
Altered iron metabolism in HIV infection: mechanisms, possible consequences, and proposals for management.
    Infectious agents and disease, 1996, Volume: 5, Issue:1

    Topics: AIDS-Related Opportunistic Infections; Chelating Agents; Deferoxamine; Hemosiderosis; HIV Infections

1996
Benefits and complications of regular blood transfusion in patients with beta-thalassaemia major.
    Vox sanguinis, 2000, Volume: 79, Issue:3

    Topics: Anemia, Hemolytic; beta-Thalassemia; Blood Group Incompatibility; Blood Transfusion; Cardiovascular

2000
The management of haemoglobinopathies.
    Bailliere's clinical haematology, 1991, Volume: 4, Issue:2

    Topics: Adolescent; Anemia, Sickle Cell; Bone Marrow Transplantation; Chelation Therapy; Child; Child, Presc

1991

Other Studies

3 other studies available for deferoxamine and HIV Coinfection

ArticleYear
Survival and complications in patients with thalassemia major treated with transfusion and deferoxamine.
    Haematologica, 2004, Volume: 89, Issue:10

    Topics: Adult; Age Factors; Arrhythmias, Cardiac; Blood Transfusion; Chelation Therapy; Cohort Studies; Defe

2004
Dose of desferrioxamine and evolution of HIV-1 infection in thalassaemic patients.
    British journal of haematology, 1994, Volume: 87, Issue:4

    Topics: Acquired Immunodeficiency Syndrome; beta-Thalassemia; Child; Deferoxamine; Disease Progression; Fema

1994
Serum ferritin, desferrioxamine, and evolution of HIV-1 infection in thalassemic patients.
    Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association, 1998, Aug-15, Volume: 18, Issue:5

    Topics: Child; Cohort Studies; Confounding Factors, Epidemiologic; Deferoxamine; Disease Progression; Dose-R

1998