Page last updated: 2024-10-25

deferoxamine and Grippe

deferoxamine has been researched along with Grippe in 1 studies

Deferoxamine: Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
desferrioxamine B : An acyclic desferrioxamine that is butanedioic acid in which one of the carboxy groups undergoes formal condensation with the primary amino group of N-(5-aminopentyl)-N-hydroxyacetamide and the second carboxy group undergoes formal condensation with the hydroxyamino group of N(1)-(5-aminopentyl)-N(1)-hydroxy-N(4)-[5-(hydroxyamino)pentyl]butanediamide. It is a siderophore native to Streptomyces pilosus biosynthesised by the DesABCD enzyme cluster as a high affinity Fe(III) chelator.

Research Excerpts

ExcerptRelevanceReference
"pneumoniae and influenza A also induced an IL-6 response."1.31Iron chelation and hydroxyl radical scavenging reduce the inflammatory response of endothelial cells after infection with Chlamydia pneumoniae or influenza A. ( Diepersloot, RJ; Marx, JJ; van Asbeck, BS; van der Bruggen, T; Verkerk, MS; Visseren, F, 2002)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Visseren, F1
Verkerk, MS1
van der Bruggen, T1
Marx, JJ1
van Asbeck, BS1
Diepersloot, RJ1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Application of Iron Chelator (Desferal) to Reduce the Severity of COVID-19 Manifestations[NCT04333550]Phase 1/Phase 250 participants (Anticipated)Interventional2020-04-30Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

1 other study available for deferoxamine and Grippe

ArticleYear
Iron chelation and hydroxyl radical scavenging reduce the inflammatory response of endothelial cells after infection with Chlamydia pneumoniae or influenza A.
    European journal of clinical investigation, 2002, Volume: 32 Suppl 1

    Topics: Antioxidants; Cells, Cultured; Chlamydophila Infections; Chlamydophila pneumoniae; Deferoxamine; End

2002