deferoxamine has been researched along with Genetic Predisposition in 5 studies
Deferoxamine: Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
desferrioxamine B : An acyclic desferrioxamine that is butanedioic acid in which one of the carboxy groups undergoes formal condensation with the primary amino group of N-(5-aminopentyl)-N-hydroxyacetamide and the second carboxy group undergoes formal condensation with the hydroxyamino group of N(1)-(5-aminopentyl)-N(1)-hydroxy-N(4)-[5-(hydroxyamino)pentyl]butanediamide. It is a siderophore native to Streptomyces pilosus biosynthesised by the DesABCD enzyme cluster as a high affinity Fe(III) chelator.
| Excerpt | Relevance | Reference |
|---|---|---|
| "These results suggest that superoxide anions in the RVLM, which generate hydroxyl radicals, are increased in SHRSP and contribute to the neural mechanisms of hypertension in SHRSP." | 3.72 | Increased reactive oxygen species in rostral ventrolateral medulla contribute to neural mechanisms of hypertension in stroke-prone spontaneously hypertensive rats. ( Hirooka, Y; Ito, K; Kimura, Y; Kishi, T; Shimokawa, H; Takeshita, A, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (60.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Elenbaas, JS | 1 |
| Maitra, D | 1 |
| Liu, Y | 1 |
| Lentz, SI | 1 |
| Nelson, B | 1 |
| Hoenerhoff, MJ | 1 |
| Shavit, JA | 1 |
| Omary, MB | 1 |
| Luckie, M | 1 |
| Irwin, B | 1 |
| Nair, S | 1 |
| Greenwood, J | 1 |
| Khattar, R | 1 |
| Obolensky, A | 1 |
| Berenshtein, E | 1 |
| Lederman, M | 1 |
| Bulvik, B | 1 |
| Alper-Pinus, R | 1 |
| Yaul, R | 1 |
| Deleon, E | 1 |
| Chowers, I | 1 |
| Chevion, M | 1 |
| Banin, E | 1 |
| Kishi, T | 1 |
| Hirooka, Y | 1 |
| Kimura, Y | 1 |
| Ito, K | 1 |
| Shimokawa, H | 1 |
| Takeshita, A | 1 |
| Wu, KH | 1 |
| Chang, JG | 1 |
| Ho, YJ | 1 |
| Wu, SF | 1 |
| Peng, CT | 1 |
5 other studies available for deferoxamine and Genetic Predisposition
| Article | Year |
|---|---|
A precursor-inducible zebrafish model of acute protoporphyria with hepatic protein aggregation and multiorganelle stress.
Topics: Aminolevulinic Acid; Animals; Deferoxamine; Disease Models, Animal; Genetic Predisposition to Diseas | 2016 |
Left ventricular non-compaction in identical twins with thalassaemia and cardiac iron overload.
Topics: beta-Thalassemia; Deferoxamine; Diseases in Twins; Echocardiography; Female; Ferritins; Genetic Pred | 2009 |
Zinc-desferrioxamine attenuates retinal degeneration in the rd10 mouse model of retinitis pigmentosa.
Topics: Animals; Biomarkers; Chelating Agents; Cyclic Nucleotide Phosphodiesterases, Type 6; Deferoxamine; D | 2011 |
Increased reactive oxygen species in rostral ventrolateral medulla contribute to neural mechanisms of hypertension in stroke-prone spontaneously hypertensive rats.
Topics: 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt; Animals; Blood Pressure; Brain Chemistry; Ca | 2004 |
Glutathione S-transferase M1 gene polymorphisms are associated with cardiac iron deposition in patients with beta-thalassemia major.
Topics: Adolescent; Adult; beta-Thalassemia; Cardiomyopathies; Chelation Therapy; Child; Combined Modality T | 2006 |