deferoxamine has been researched along with Fractures, Bone in 5 studies
Deferoxamine: Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
desferrioxamine B : An acyclic desferrioxamine that is butanedioic acid in which one of the carboxy groups undergoes formal condensation with the primary amino group of N-(5-aminopentyl)-N-hydroxyacetamide and the second carboxy group undergoes formal condensation with the hydroxyamino group of N(1)-(5-aminopentyl)-N(1)-hydroxy-N(4)-[5-(hydroxyamino)pentyl]butanediamide. It is a siderophore native to Streptomyces pilosus biosynthesised by the DesABCD enzyme cluster as a high affinity Fe(III) chelator.
Fractures, Bone: Breaks in bones.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Facilitation of osteoblast apoptosis occurred regardless of IND dosage under hypoxic conditions." | 1.38 | Facilitation of human osteoblast apoptosis by sulindac and indomethacin under hypoxic injury. ( Chang, CH; Chen, YC; Fan, SC; Huang, CH; Liu, C; Tsai, AL; Wu, CC, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (20.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pfeiffenberger, M | 1 |
| Hoff, P | 1 |
| Thöne-Reineke, C | 1 |
| Buttgereit, F | 1 |
| Lang, A | 1 |
| Gaber, T | 1 |
| Liu, C | 1 |
| Tsai, AL | 1 |
| Chen, YC | 1 |
| Fan, SC | 1 |
| Huang, CH | 1 |
| Wu, CC | 1 |
| Chang, CH | 1 |
| de Sanctis, V | 1 |
| Stea, S | 1 |
| Savarino, L | 1 |
| Granchi, D | 1 |
| Visentin, M | 1 |
| Sprocati, M | 1 |
| Govoni, R | 1 |
| Pizzoferrato, A | 1 |
| Orvieto, R | 1 |
| Leichter, I | 1 |
| Rachmilewitz, EA | 1 |
| Margulies, JY | 1 |
| O'Shaughnessy, MC | 1 |
| Brunström, GM | 1 |
| Fielding, J | 1 |
5 other studies available for deferoxamine and Fractures, Bone
| Article | Year |
|---|---|
The in vitro human fracture hematoma model - a tool for preclinical drug testing.
Topics: Animal Testing Alternatives; Anti-Inflammatory Agents; Deferoxamine; Dexamethasone; Fractures, Bone; | 2020 |
Facilitation of human osteoblast apoptosis by sulindac and indomethacin under hypoxic injury.
Topics: Alkaline Phosphatase; Animals; Apoptosis; Aspirin; Cell Hypoxia; Cell Line, Tumor; Cell Survival; Ce | 2012 |
Osteochondrodystrophic lesions in chelated thalassemic patients: an histological analysis.
Topics: Adolescent; Biopsy; Bone Diseases; Cartilage; Chelating Agents; Child; Deferoxamine; Female; Fractur | 2000 |
Bone density, mineral content, and cortical index in patients with thalassemia major and the correlation to their bone fractures, blood transfusions, and treatment with desferrioxamine.
Topics: Adolescent; Adult; Blood Transfusion; Bone and Bones; Bone Density; Child; Deferoxamine; Female; Fra | 1992 |
Iron chelation in haematomas at fracture sites.
Topics: Adult; Deferoxamine; Female; Fractures, Bone; Hematoma; Hemoglobins; Humans; Iron; Iron Chelating Ag | 1966 |