Page last updated: 2024-10-25

deferoxamine and Fatty Liver

deferoxamine has been researched along with Fatty Liver in 2 studies

Deferoxamine: Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
desferrioxamine B : An acyclic desferrioxamine that is butanedioic acid in which one of the carboxy groups undergoes formal condensation with the primary amino group of N-(5-aminopentyl)-N-hydroxyacetamide and the second carboxy group undergoes formal condensation with the hydroxyamino group of N(1)-(5-aminopentyl)-N(1)-hydroxy-N(4)-[5-(hydroxyamino)pentyl]butanediamide. It is a siderophore native to Streptomyces pilosus biosynthesised by the DesABCD enzyme cluster as a high affinity Fe(III) chelator.

Fatty Liver: Lipid infiltration of the hepatic parenchymal cells resulting in a yellow-colored liver. The abnormal lipid accumulation is usually in the form of TRIGLYCERIDES, either as a single large droplet or multiple small droplets. Fatty liver is caused by an imbalance in the metabolism of FATTY ACIDS.

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19901 (50.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fargion, S1
Dongiovanni, P1
Guzzo, A1
Colombo, S1
Valenti, L1
Fracanzani, AL1
MacDonald, RA1
MacSween, RN1
Pechet, GS1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Role of Gut Hormones and Hepcidin in Type 2 Diabetes Mellitus[NCT02413762]1,512 participants (Actual)Observational2015-03-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

2 other studies available for deferoxamine and Fatty Liver

ArticleYear
Iron and insulin resistance.
    Alimentary pharmacology & therapeutics, 2005, Volume: 22 Suppl 2

    Topics: Cell Line, Tumor; Deferoxamine; Diet; Energy Intake; Fatty Liver; Female; Gene Expression; Glucokina

2005
Iron metabolism by reticuloendothelial cells in vitro. Physical and chemical conditions, lipotrope deficiency, and acute inflammation.
    Laboratory investigation; a journal of technical methods and pathology, 1969, Volume: 21, Issue:3

    Topics: Animals; Ascorbic Acid; Cobalt; Copper; Cysteine; Dactinomycin; Deferoxamine; Dinitrophenols; Edetic

1969