deferoxamine has been researched along with Fatty Liver, Nonalcoholic in 3 studies
Deferoxamine: Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
desferrioxamine B : An acyclic desferrioxamine that is butanedioic acid in which one of the carboxy groups undergoes formal condensation with the primary amino group of N-(5-aminopentyl)-N-hydroxyacetamide and the second carboxy group undergoes formal condensation with the hydroxyamino group of N(1)-(5-aminopentyl)-N(1)-hydroxy-N(4)-[5-(hydroxyamino)pentyl]butanediamide. It is a siderophore native to Streptomyces pilosus biosynthesised by the DesABCD enzyme cluster as a high affinity Fe(III) chelator.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Furthermore, NAFLD patients with hepatic RES iron deposition had increased hepatic gene expression levels of M1 markers, IL-6, IL-1β, and CD40 and reduced gene expression of an M2 marker, TGM2, relative to patients with hepatocellular iron deposition pattern." | 1.51 | Iron alters macrophage polarization status and leads to steatohepatitis and fibrogenesis. ( Boukhar, S; Gochanour, E; Handa, P; Kowdley, KV; Maliken, BD; Morgan-Stevenson, V; Thomas, S; Yeh, MM, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Kim, KM | 1 |
| Cho, SS | 1 |
| Ki, SH | 1 |
| Handa, P | 1 |
| Thomas, S | 1 |
| Morgan-Stevenson, V | 1 |
| Maliken, BD | 1 |
| Gochanour, E | 1 |
| Boukhar, S | 1 |
| Yeh, MM | 1 |
| Kowdley, KV | 1 |
| Xue, H | 1 |
| Chen, D | 1 |
| Zhong, YK | 1 |
| Zhou, ZD | 1 |
| Fang, SX | 1 |
| Li, MY | 1 |
| Guo, C | 1 |
1 review available for deferoxamine and Fatty Liver, Nonalcoholic
| Article | Year |
|---|---|
Emerging roles of ferroptosis in liver pathophysiology.
Topics: Animals; Antineoplastic Agents; Caffeic Acids; Carcinoma, Hepatocellular; Cycloheximide; Cyclohexyla | 2020 |
2 other studies available for deferoxamine and Fatty Liver, Nonalcoholic
| Article | Year |
|---|---|
Iron alters macrophage polarization status and leads to steatohepatitis and fibrogenesis.
Topics: Adult; Animals; Chemokine CCL2; Deferoxamine; Diet, Fat-Restricted; Female; Femur; Ferric Compounds; | 2019 |
Deferoxamine ameliorates hepatosteatosis via several mechanisms in ob/ob mice.
Topics: Animals; Apoptosis Regulatory Proteins; Body Weight; Deferoxamine; Feeding Behavior; Gene Expression | 2016 |