deferoxamine has been researched along with Eye Diseases in 24 studies
Deferoxamine: Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
desferrioxamine B : An acyclic desferrioxamine that is butanedioic acid in which one of the carboxy groups undergoes formal condensation with the primary amino group of N-(5-aminopentyl)-N-hydroxyacetamide and the second carboxy group undergoes formal condensation with the hydroxyamino group of N(1)-(5-aminopentyl)-N(1)-hydroxy-N(4)-[5-(hydroxyamino)pentyl]butanediamide. It is a siderophore native to Streptomyces pilosus biosynthesised by the DesABCD enzyme cluster as a high affinity Fe(III) chelator.
Eye Diseases: Diseases affecting the eye.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To review the adverse effects and risks of deferoxamine for the treatment of iron poisoning." | 8.79 | Risks of parenteral deferoxamine for acute iron poisoning. ( Howland, MA, 1996) |
| "To review the adverse effects and risks of deferoxamine for the treatment of iron poisoning." | 4.79 | Risks of parenteral deferoxamine for acute iron poisoning. ( Howland, MA, 1996) |
| " The severe toxic effects on vision, hearing and growth are all more likely at higher doses of DF and there appears to be partial protection against them by iron overload." | 2.38 | The toxic effects of desferrioxamine. ( Huehns, ER; Porter, JB, 1989) |
| "Deferoxamine can cause ocular toxicity resulting in severe and permanent lesions of the retinal pigment epithelium." | 1.31 | [Ocular toxicity of deferoxamine: description and analysis of three observations]. ( Flament, J; Mack, G; Szwarcberg, J, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 18 (75.00) | 18.7374 |
| 1990's | 4 (16.67) | 18.2507 |
| 2000's | 1 (4.17) | 29.6817 |
| 2010's | 1 (4.17) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| El-Shazly, AA | 1 |
| Ebeid, WM | 1 |
| Elkitkat, RS | 1 |
| Deghedy, MR | 1 |
| Szwarcberg, J | 1 |
| Mack, G | 1 |
| Flament, J | 1 |
| CHAVANNE, H | 1 |
| DEMILLIERE, B | 1 |
| Valvo, A | 2 |
| Declercq, SS | 1 |
| Krawczuk-Hermanowicz, O | 1 |
| Smolińska, K | 1 |
| Dennerlein, JA | 1 |
| Lang, GE | 1 |
| Stahnke, K | 1 |
| Kleihauer, E | 1 |
| Lang, GK | 1 |
| Howland, MA | 1 |
| Sánchez Rodríguez, A | 1 |
| Martín Oterino, JA | 1 |
| Fidalgo Fernández, MA | 1 |
| Sorcinelli, R | 1 |
| Sitzia, A | 1 |
| Figus, A | 1 |
| Lai, ME | 1 |
| Porter, JB | 1 |
| Huehns, ER | 1 |
| Pall, H | 1 |
| Blake, DR | 1 |
| Winyard, P | 1 |
| Lunec, J | 1 |
| Williams, A | 1 |
| Good, PA | 1 |
| Kritzinger, EE | 1 |
| Cornish, A | 1 |
| Hider, RC | 1 |
| De Doncker, R | 1 |
| Casteels, I | 1 |
| Leys, A | 1 |
| Missotten, L | 1 |
| Gerkowicz, K | 1 |
| Prost, M | 1 |
| van Oye, R | 1 |
| Campana, G | 2 |
| Boschi, MC | 2 |
| Bessière, E | 1 |
| Verin, P | 1 |
| Le Rebeller, MJ | 1 |
| Descamp, F | 1 |
| Norn, MS | 1 |
| Luongo, E | 1 |
| Lange, J | 1 |
| Del Duca, A | 1 |
| Wise, JB | 1 |
| Falbe-Hansen, I | 1 |
2 reviews available for deferoxamine and Eye Diseases
| Article | Year |
|---|---|
Risks of parenteral deferoxamine for acute iron poisoning.
Topics: Administration, Oral; Antidotes; Communicable Diseases; Deferoxamine; Ear Diseases; Eye Diseases; Hu | 1996 |
The toxic effects of desferrioxamine.
Topics: Animals; Blood-Brain Barrier; Deferoxamine; Disease Susceptibility; Eye Diseases; Growth Disorders; | 1989 |
22 other studies available for deferoxamine and Eye Diseases
| Article | Year |
|---|---|
ELECTRORETINOGRAPHIC AND VISUAL-EVOKED POTENTIAL CHANGES IN RELATION TO CHELATION MODALITY IN CHILDREN WITH THALASSEMIA.
Topics: Administration, Oral; Adolescent; Benzoates; Cross-Sectional Studies; Deferasirox; Deferoxamine; Dos | 2017 |
[Ocular toxicity of deferoxamine: description and analysis of three observations].
Topics: Aged; Deferoxamine; Eye Diseases; Female; Humans; Iron Chelating Agents | 2002 |
[TRIAL OF A NEW IRON CHELATOR, DESFERRIOXAMINE B, IN A CASE OF OCULAR SIDEROSIS].
Topics: Chelating Agents; Deferoxamine; Eye Diseases; Heavy Metal Poisoning; Humans; Iron; Iron Metabolism D | 1964 |
Desferrioxamine B in ophthalmology. Applications and therapeutic possibilities.
Topics: Adult; Animals; Cornea; Deferoxamine; Eye Diseases; Eye Foreign Bodies; Humans; Male; Rabbits; Sider | 1967 |
Desferrioxamine in ocular siderosis: a long-term electrophysiological evaluation.
Topics: Animals; Deferoxamine; Electroretinography; Eye Diseases; Eye Foreign Bodies; Rabbits; Siderosis | 1980 |
[Clinical aspects of ocular siderosis].
Topics: Adult; Deferoxamine; Eye Diseases; Eye Foreign Bodies; Humans; Hydroxamic Acids; Iron; Male; Sideros | 1980 |
[Ocular findings in Desferal therapy].
Topics: Adolescent; Adult; beta-Thalassemia; Child; Child, Preschool; Deferoxamine; Dose-Response Relationsh | 1995 |
Unusual toxicity of deferoxamine.
Topics: Chelating Agents; Deferoxamine; Eye Diseases; Humans; Male; Middle Aged; Renal Dialysis | 1999 |
Ocular findings in beta-thalassemia.
Topics: Adolescent; Adult; Blood Transfusion; Cataract; Child; Deferoxamine; Eye Diseases; Female; Humans; M | 1990 |
Ocular toxicity of desferrioxamine--an example of copper promoted auto-oxidative damage?
Topics: Aged; Copper; Deferoxamine; Electrooculography; Electroretinography; Evoked Potentials, Visual; Eye | 1989 |
Desferroxamine and ocular toxicity, causal or concomitant relationship.
Topics: Adolescent; Adult; Child; Child, Preschool; Deferoxamine; Eye Diseases; Fluorescein Angiography; Hum | 1986 |
Studies on the use of desferrioxamine in experimental ocular siderosis produced by extrabulbar administration of iron.
Topics: Animals; Deferoxamine; Eye; Eye Diseases; Eye Foreign Bodies; Iron; Rabbits; Siderosis | 1985 |
[Harmful effects of common drugs on the visual apparatus. The oligo-elements and chelating agents. B. Chelating agents].
Topics: Chelating Agents; Deferoxamine; Dimercaprol; Edetic Acid; Eye Diseases; Humans; Penicillamine; Visio | 1972 |
[Clinical and experimental results of the treatment of some ocular diseases with desferrioxamine B].
Topics: Adolescent; Adult; Animals; Cornea; Deferoxamine; Eye Diseases; Eye Foreign Bodies; Hemorrhage; Huma | 1969 |
[Case of ocular siderosis ameliorated by deferoxamine].
Topics: Deferoxamine; Electroretinography; Eye Diseases; Humans; Male; Middle Aged; Siderosis | 1967 |
Hudson-Stähli's line of cornea. I. Incidence and morphology.
Topics: Adolescent; Adult; Aged; Child; Cornea; Deferoxamine; Diagnosis, Differential; Eye Diseases; Female; | 1968 |
[Experimental and clinical studies on the influence of desferrioxamine B on various ocular diseases. Preliminary note on corneal apoplexy].
Topics: Adolescent; Animals; Cornea; Deferoxamine; Eye Diseases; Humans; Male; Middle Aged; Rabbits | 1968 |
[Treatment of ocular siderosis with desferrioxamine B].
Topics: Adolescent; Adult; Deferoxamine; Eye Diseases; Eye Foreign Bodies; Eye Injuries; Humans; Male; Sider | 1968 |
[Chemica damage to the eye in industrial medicine].
Topics: Argyria; Burns, Chemical; Caustics; Chelating Agents; Chronic Disease; Copper; Deferoxamine; Dimerca | 1969 |
[Applications of a new chelating substance in ophthalmology. Therapeutic results in a case of ocular siderosis treated with desferrioxamine B].
Topics: Adult; Deferoxamine; Eye Diseases; Eye Foreign Bodies; Female; Humans; Siderosis | 1965 |
Treatment of experimental siderosis bulbi, vitreous hemorrhage, and corneal blood staining with deferoxamine.
Topics: Animals; Blood Stains; Cornea; Deferoxamine; Eye Diseases; Hemorrhage; In Vitro Techniques; Rabbits; | 1966 |
Treatment of ocular siderosis and haemochromatosis with desferrioxamine.
Topics: Deferoxamine; Eye Diseases; Eye Foreign Bodies; Eye Injuries; Hemorrhage; Humans; Injections, Intram | 1966 |