deferoxamine has been researched along with Experimental Neoplasms in 12 studies
Deferoxamine: Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
desferrioxamine B : An acyclic desferrioxamine that is butanedioic acid in which one of the carboxy groups undergoes formal condensation with the primary amino group of N-(5-aminopentyl)-N-hydroxyacetamide and the second carboxy group undergoes formal condensation with the hydroxyamino group of N(1)-(5-aminopentyl)-N(1)-hydroxy-N(4)-[5-(hydroxyamino)pentyl]butanediamide. It is a siderophore native to Streptomyces pilosus biosynthesised by the DesABCD enzyme cluster as a high affinity Fe(III) chelator.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Cells from a rat hepatoma grown in culture were found to activate methyldopa to intermediates which are bound irreversibly to cellular proteins." | 1.26 | Methyldopa binding to cells in culture. ( Dybing, E, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (58.33) | 18.7374 |
| 1990's | 2 (16.67) | 18.2507 |
| 2000's | 2 (16.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (8.33) | 2.80 |
| Authors | Studies |
|---|---|
| Komoto, K | 1 |
| Nomoto, T | 1 |
| El Muttaqien, S | 1 |
| Takemoto, H | 1 |
| Matsui, M | 1 |
| Miura, Y | 1 |
| Nishiyama, N | 1 |
| Nevo, I | 1 |
| Sagi-Assif, O | 1 |
| Edry Botzer, L | 1 |
| Amar, D | 1 |
| Maman, S | 1 |
| Kariv, N | 1 |
| Leider-Trejo, LE | 1 |
| Savelyeva, L | 1 |
| Schwab, M | 1 |
| Yron, I | 1 |
| Witz, IP | 1 |
| Erez, N | 1 |
| Milyavsky, M | 1 |
| Eilam, R | 1 |
| Shats, I | 1 |
| Goldfinger, N | 1 |
| Rotter, V | 1 |
| Hammersley, PA | 1 |
| Sephton, RG | 2 |
| De Abrew, S | 2 |
| Hodgson, GS | 1 |
| Mathias, CJ | 1 |
| Wang, S | 1 |
| Lee, RJ | 1 |
| Waters, DJ | 1 |
| Low, PS | 1 |
| Green, MA | 1 |
| Kemp, JD | 1 |
| Dybing, E | 1 |
| Hoffer, PB | 1 |
| Samuel, A | 1 |
| Bushberg, JT | 1 |
| Thakur, M | 1 |
| Koizumi, M | 1 |
| Endo, K | 1 |
| Kunimatsu, M | 1 |
| Sakahara, H | 1 |
| Nakashima, T | 1 |
| Kawamura, Y | 1 |
| Watanabe, Y | 1 |
| Saga, T | 1 |
| Konishi, J | 1 |
| Yamamuro, T | 1 |
| Brockman, RW | 1 |
2 reviews available for deferoxamine and Experimental Neoplasms
| Article | Year |
|---|---|
Iron deprivation and cancer: a view beginning with studies of monoclonal antibodies against the transferrin receptor.
Topics: Animals; Antibodies, Monoclonal; Antineoplastic Agents; Deferoxamine; Gallium; Humans; Iron; Mice; N | 1997 |
Biochemical aspects of drug combinations.
Topics: Alkylating Agents; Animals; Antineoplastic Agents; Bleomycin; Camptothecin; Cell Division; Cytarabin | 1974 |
10 other studies available for deferoxamine and Experimental Neoplasms
| Article | Year |
|---|---|
Iron chelation cancer therapy using hydrophilic block copolymers conjugated with deferoxamine.
Topics: Animals; Apoptosis; Cell Line, Tumor; Cell Proliferation; Deferoxamine; Drug Carriers; Iron Chelatin | 2021 |
Generation and characterization of novel local and metastatic human neuroblastoma variants.
Topics: Adrenal Gland Neoplasms; Animals; Cell Line, Tumor; Cell Proliferation; Deferoxamine; Disease Models | 2008 |
Expression of prolyl-hydroxylase-1 (PHD1/EGLN2) suppresses hypoxia inducible factor-1alpha activation and inhibits tumor growth.
Topics: Animals; Cell Division; Cell Hypoxia; Deferoxamine; DNA-Binding Proteins; HCT116 Cells; Humans; Hypo | 2003 |
Relative tumour enhancement of 67Ga uptake by desferrioxamine.
Topics: Animals; Deferoxamine; Gallium Radioisotopes; Male; Mice; Mice, Inbred BALB C; Neoplasm Transplantat | 1984 |
Mechanisms of distribution of gallium 67 in mouse tumour hosts.
Topics: Animals; Deferoxamine; Gallium Radioisotopes; Iron Radioisotopes; Kinetics; Male; Mice; Mice, Inbred | 1982 |
Tumor-selective radiopharmaceutical targeting via receptor-mediated endocytosis of gallium-67-deferoxamine-folate.
Topics: Animals; Carrier Proteins; Deferoxamine; Endocytosis; Folate Receptors, GPI-Anchored; Folic Acid; Ma | 1996 |
Methyldopa binding to cells in culture.
Topics: Acetaminophen; Allopurinol; Animals; Ascorbic Acid; Carcinoma, Hepatocellular; Cells, Cultured; Defe | 1977 |
Desferoxamine mesylate (Desferal): a contrast-enhancing agent for gallium-37 imaging.
Topics: Abscess; Animals; Deferoxamine; Drug Interactions; Gallium Radioisotopes; Image Enhancement; Melanom | 1979 |
Effects of desferrioxamine on 67Ga distributions in tumor-bearing mice.
Topics: Animals; Binding Sites; Deferoxamine; Gallium Radioisotopes; Iron Radioisotopes; Lymphoma; Male; Mic | 1979 |
67Ga-labeled antibodies for immunoscintigraphy and evaluation of tumor targeting of drug-antibody conjugates in mice.
Topics: Animals; Antibodies, Monoclonal; Deferoxamine; Drug Stability; Gallium Radioisotopes; Mice; Neoplasm | 1988 |