deferoxamine has been researched along with Experimental Mammary Neoplasms in 7 studies
Deferoxamine: Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
desferrioxamine B : An acyclic desferrioxamine that is butanedioic acid in which one of the carboxy groups undergoes formal condensation with the primary amino group of N-(5-aminopentyl)-N-hydroxyacetamide and the second carboxy group undergoes formal condensation with the hydroxyamino group of N(1)-(5-aminopentyl)-N(1)-hydroxy-N(4)-[5-(hydroxyamino)pentyl]butanediamide. It is a siderophore native to Streptomyces pilosus biosynthesised by the DesABCD enzyme cluster as a high affinity Fe(III) chelator.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In conclusion, breast cancer cells up-regulate the expression of iron importer genes and down-regulate the expression of iron exporter SLC40A1 to satisfy their increased demand for iron." | 1.36 | Manipulation of iron transporter genes results in the suppression of human and mouse mammary adenocarcinomas. ( Elliott, RL; Head, JF; Jiang, XP, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (14.29) | 18.7374 |
| 1990's | 3 (42.86) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (42.86) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Seo, JW | 1 |
| Mahakian, LM | 1 |
| Tam, S | 1 |
| Qin, S | 1 |
| Ingham, ES | 1 |
| Meares, CF | 1 |
| Ferrara, KW | 1 |
| Jiang, XP | 1 |
| Elliott, RL | 1 |
| Head, JF | 1 |
| Kanojia, D | 1 |
| Zhou, W | 1 |
| Zhang, J | 1 |
| Jie, C | 1 |
| Lo, PK | 1 |
| Wang, Q | 1 |
| Chen, H | 1 |
| Parkins, CS | 1 |
| Holder, AL | 1 |
| Dennis, MF | 1 |
| Stratford, MR | 1 |
| Chaplin, DJ | 1 |
| Soybir, G | 1 |
| Köksoy, F | 1 |
| Koyuncu, H | 1 |
| Yalçin, O | 1 |
| Köse, H | 1 |
| Topuzlu, C | 1 |
| Holmes, KT | 1 |
| Lean, CL | 1 |
| Hunt, NH | 1 |
| King, NJ | 1 |
| Hunt, FC | 1 |
7 other studies available for deferoxamine and Experimental Mammary Neoplasms
| Article | Year |
|---|---|
The pharmacokinetics of Zr-89 labeled liposomes over extended periods in a murine tumor model.
Topics: Animals; Chemistry, Pharmaceutical; Deferoxamine; Disease Models, Animal; Drug Stability; Humans; Is | 2015 |
Manipulation of iron transporter genes results in the suppression of human and mouse mammary adenocarcinomas.
Topics: Adenocarcinoma; Animals; Breast Neoplasms; Cation Transport Proteins; Cell Line, Tumor; Chlorides; D | 2010 |
Proteomic profiling of cancer stem cells derived from primary tumors of HER2/Neu transgenic mice.
Topics: Animals; Biomarkers, Tumor; Blotting, Western; Cell Culture Techniques; Computer Simulation; Deferox | 2012 |
Involvement of oxygen free radicals in ischaemia-reperfusion injury to murine tumours: role of nitric oxide.
Topics: Adenocarcinoma; Animals; Catalase; Deferoxamine; Endothelium, Vascular; Female; Free Radical Scaveng | 1998 |
Chemoprevention of DMBA-induced mammary gland carcinogenesis--preventive effects of free oxygen radical scavengers.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Calcium Channel Blockers; Carcin | 1998 |
Development of the "activated" high resolution 1H MR spectrum in murine T cells and B cells occurs in G1 phase of the cell cycle.
Topics: Adenocarcinoma; Animals; B-Lymphocytes; Cells, Cultured; Deferoxamine; G1 Phase; Hydroxyurea; Lympho | 1990 |
Chelator-induced enhancement of 67Ga tumour imaging: comparison of desferrioxamine with N,N'-ethylene-bis[2-hydroxy-5-carboxyphenylglycine].
Topics: Animals; Chelating Agents; Citrates; Citric Acid; Deferoxamine; Ethylenediamines; Leukemia, Lymphoid | 1988 |