deferoxamine has been researched along with Enlarged Spleen in 5 studies
Deferoxamine: Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
desferrioxamine B : An acyclic desferrioxamine that is butanedioic acid in which one of the carboxy groups undergoes formal condensation with the primary amino group of N-(5-aminopentyl)-N-hydroxyacetamide and the second carboxy group undergoes formal condensation with the hydroxyamino group of N(1)-(5-aminopentyl)-N(1)-hydroxy-N(4)-[5-(hydroxyamino)pentyl]butanediamide. It is a siderophore native to Streptomyces pilosus biosynthesised by the DesABCD enzyme cluster as a high affinity Fe(III) chelator.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Iron overload was a frequent complication." | 2.42 | Congenital dyserythropoietic anemia type II: epidemiology, clinical appearance, and prognosis based on long-term observation. ( Anselstetter, V; Chrobak, L; Denecke, J; Einsiedler, B; Gallmeier, K; Griesshammer, A; Heimpel, H; Janka-Schaub, G; Kohne, E; Kron, M; Marquardt, T, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (80.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Heimpel, H | 1 |
| Anselstetter, V | 1 |
| Chrobak, L | 1 |
| Denecke, J | 1 |
| Einsiedler, B | 1 |
| Gallmeier, K | 1 |
| Griesshammer, A | 1 |
| Marquardt, T | 1 |
| Janka-Schaub, G | 1 |
| Kron, M | 1 |
| Kohne, E | 1 |
| REWALD, EF | 1 |
| Triadou, P | 1 |
| Girot, R | 1 |
| Lapoumeroulie, C | 1 |
| Pomarede, R | 1 |
| Constant, S | 1 |
| Vadász, G | 1 |
| Wolman, IJ | 1 |
| Ortolani, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Safety & Efficacy of Thalidomide in Children With Transfusion Dependent Thalassemia: a Quasi Randomized Control Trial in a Tertiary Care Hospital in Bangladesh[NCT06098014] | Phase 3 | 60 participants (Anticipated) | Interventional | 2023-03-08 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for deferoxamine and Enlarged Spleen
| Article | Year |
|---|---|
Congenital dyserythropoietic anemia type II: epidemiology, clinical appearance, and prognosis based on long-term observation.
Topics: Adolescent; Adult; Aged; Anemia, Dyserythropoietic, Congenital; Child; Child, Preschool; Cholelithia | 2003 |
4 other studies available for deferoxamine and Enlarged Spleen
| Article | Year |
|---|---|
[PREVENTION OF HYPERACTIVE ERYTHROPOIESIS AS A THERAPEUTIC CRITERION IN THALASSEMIA AND OTHER CORPUSCULAR ANEMIAS. PRELIMINARY NOTE].
Topics: Anemia; Blood Transfusion; Deferoxamine; Erythropoiesis; Humans; Hydroxamic Acids; Infant; Splenomeg | 1963 |
[Thalassaemia intermedia. Clinical and laboratory study. Therapeutic suggestions (author's transl)].
Topics: Age Factors; Blood Transfusion; Child; Child, Preschool; Deferoxamine; Female; Fetal Hemoglobin; Hem | 1982 |
[A case of Diamond-Blackfan anemia: Experiences of 10-year follow-up study].
Topics: Adolescent; Anemia, Aplastic; Biopsy; Blood Transfusion; Child; Child, Preschool; Deferoxamine; Eryt | 1974 |
Some clinical features of Cooley's anemia patients as related to transfusion schedules.
Topics: Blood Transfusion; Deferoxamine; Fetal Hemoglobin; Growth Disorders; Hematopoiesis; Humans; Iron; Li | 1969 |