deferoxamine has been researched along with Endotoxin Shock in 6 studies
Deferoxamine: Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
desferrioxamine B : An acyclic desferrioxamine that is butanedioic acid in which one of the carboxy groups undergoes formal condensation with the primary amino group of N-(5-aminopentyl)-N-hydroxyacetamide and the second carboxy group undergoes formal condensation with the hydroxyamino group of N(1)-(5-aminopentyl)-N(1)-hydroxy-N(4)-[5-(hydroxyamino)pentyl]butanediamide. It is a siderophore native to Streptomyces pilosus biosynthesised by the DesABCD enzyme cluster as a high affinity Fe(III) chelator.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Treatment with gadolinium chloride (GdCl3) selectively reduced the capacity of Kupffer cells to generate superoxide by 65% and attenuated liver injury by 73% at 4 h and 58-69% at 24 h." | 1.29 | Activation of Kupffer cells and neutrophils for reactive oxygen formation is responsible for endotoxin-enhanced liver injury after hepatic ischemia. ( Farhood, A; Fisher, MA; Jaeschke, H; Liu, P; McGuire, GM; Smith, CW, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (50.00) | 18.7374 |
| 1990's | 2 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, S | 1 |
| Liu, C | 1 |
| Pan, S | 1 |
| Miao, Q | 1 |
| Xue, J | 1 |
| Xun, J | 1 |
| Zhang, Y | 1 |
| Gao, Y | 1 |
| Duan, X | 1 |
| Fan, Y | 1 |
| WHITTEN, CF | 1 |
| Liu, P | 1 |
| McGuire, GM | 1 |
| Fisher, MA | 1 |
| Farhood, A | 1 |
| Smith, CW | 1 |
| Jaeschke, H | 1 |
| Kazmierski, WM | 1 |
| Wolberg, G | 1 |
| Wilson, JG | 1 |
| Smith, SR | 1 |
| Williams, DS | 1 |
| Thorp, HH | 1 |
| Molina, L | 1 |
| Dumont-Senaneuch, C | 1 |
| Floret, D | 1 |
| Philippe, N | 1 |
| Lavender, S | 1 |
| Bell, JA | 1 |
6 other studies available for deferoxamine and Endotoxin Shock
| Article | Year |
|---|---|
Deferoxamine attenuates lipopolysaccharide-induced inflammatory responses and protects against endotoxic shock in mice.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Line; Deferoxamine; Dinoprostone; Extracellul | 2015 |
ACCIDENTAL IRON POISONING IN CHILDREN.
Topics: Accident Prevention; Acidosis; Bicarbonates; Chelating Agents; Child; Deferoxamine; Dogs; Humans; Hy | 1963 |
Activation of Kupffer cells and neutrophils for reactive oxygen formation is responsible for endotoxin-enhanced liver injury after hepatic ischemia.
Topics: Animals; Antibodies, Monoclonal; CD11 Antigens; Chromans; Deferoxamine; Gadolinium; Ischemia; Kupffe | 1995 |
Iron chelates bind nitric oxide and decrease mortality in an experimental model of septic shock.
Topics: Animals; Corynebacterium Infections; Deferoxamine; Electric Conductivity; Ferric Compounds; Iron Che | 1996 |
[Fatal Yersinia enterocolitica septic shock in a child with chronic anemia].
Topics: Anemia, Hemolytic, Congenital; Child, Preschool; Deferoxamine; Humans; Male; Risk Factors; Shock, Se | 1988 |
Iron intoxication in an adult.
Topics: Acidosis; Adult; Anuria; Deferoxamine; Female; Humans; Iron; Peritoneal Dialysis; Poisoning; Shock, | 1970 |