deferoxamine has been researched along with Endotoxemia in 4 studies
Deferoxamine: Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
desferrioxamine B : An acyclic desferrioxamine that is butanedioic acid in which one of the carboxy groups undergoes formal condensation with the primary amino group of N-(5-aminopentyl)-N-hydroxyacetamide and the second carboxy group undergoes formal condensation with the hydroxyamino group of N(1)-(5-aminopentyl)-N(1)-hydroxy-N(4)-[5-(hydroxyamino)pentyl]butanediamide. It is a siderophore native to Streptomyces pilosus biosynthesised by the DesABCD enzyme cluster as a high affinity Fe(III) chelator.
Endotoxemia: A condition characterized by the presence of ENDOTOXINS in the blood. On lysis, the outer cell wall of gram-negative bacteria enters the systemic circulation and initiates a pathophysiologic cascade of pro-inflammatory mediators.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Lactoferrin pretreatment of cells decreased LPS-mediated oxidative insults in a dose-dependent manner." | 5.36 | Lactoferrin decreases LPS-induced mitochondrial dysfunction in cultured cells and in animal endotoxemia model. ( Actor, JK; Bacsi, A; Boldogh, I; Kruzel, ML; Radak, Z; Saavedra-Molina, A, 2010) |
| "Lactoferrin pretreatment of cells decreased LPS-mediated oxidative insults in a dose-dependent manner." | 1.36 | Lactoferrin decreases LPS-induced mitochondrial dysfunction in cultured cells and in animal endotoxemia model. ( Actor, JK; Bacsi, A; Boldogh, I; Kruzel, ML; Radak, Z; Saavedra-Molina, A, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cermanova, J | 1 |
| Kadova, Z | 1 |
| Dolezelova, E | 1 |
| Zagorova, M | 1 |
| Safka, V | 1 |
| Hroch, M | 1 |
| Laho, T | 1 |
| Holeckova, M | 1 |
| Mokry, J | 1 |
| Kovarikova, P | 1 |
| Bures, J | 1 |
| Sterba, M | 1 |
| Micuda, S | 1 |
| Kruzel, ML | 1 |
| Actor, JK | 1 |
| Radak, Z | 1 |
| Bacsi, A | 1 |
| Saavedra-Molina, A | 1 |
| Boldogh, I | 1 |
| Hod, EA | 1 |
| Zhang, N | 1 |
| Sokol, SA | 1 |
| Wojczyk, BS | 1 |
| Francis, RO | 1 |
| Ansaldi, D | 1 |
| Francis, KP | 1 |
| Della-Latta, P | 1 |
| Whittier, S | 1 |
| Sheth, S | 1 |
| Hendrickson, JE | 1 |
| Zimring, JC | 1 |
| Brittenham, GM | 1 |
| Spitalnik, SL | 1 |
| Sakaguchi, S | 1 |
| Iizuka, Y | 1 |
| Furusawa, S | 1 |
| Takayanagi, M | 1 |
| Satoh, S | 1 |
4 other studies available for deferoxamine and Endotoxemia
| Article | Year |
|---|---|
Deferoxamine but not dexrazoxane alleviates liver injury induced by endotoxemia in rats.
Topics: Animals; Deferoxamine; Dexrazoxane; Endotoxemia; Iron Chelating Agents; Liver Diseases; Male; Rats; | 2014 |
Lactoferrin decreases LPS-induced mitochondrial dysfunction in cultured cells and in animal endotoxemia model.
Topics: Animals; Deferoxamine; Disease Models, Animal; DNA Damage; Dose-Response Relationship, Immunologic; | 2010 |
Transfusion of red blood cells after prolonged storage produces harmful effects that are mediated by iron and inflammation.
Topics: Acute-Phase Reaction; Animals; Blood Preservation; Deferoxamine; Disease Models, Animal; Endotoxemia | 2010 |
Haem metabolic aspects on nitric oxide formation in endotoxaemia.
Topics: Animals; Cell Line; Ceruloplasmin; Cobalt; Cytochrome P-450 Enzyme System; Deferoxamine; Endotoxemia | 2001 |