deferoxamine has been researched along with E coli Infections in 8 studies
Deferoxamine: Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
desferrioxamine B : An acyclic desferrioxamine that is butanedioic acid in which one of the carboxy groups undergoes formal condensation with the primary amino group of N-(5-aminopentyl)-N-hydroxyacetamide and the second carboxy group undergoes formal condensation with the hydroxyamino group of N(1)-(5-aminopentyl)-N(1)-hydroxy-N(4)-[5-(hydroxyamino)pentyl]butanediamide. It is a siderophore native to Streptomyces pilosus biosynthesised by the DesABCD enzyme cluster as a high affinity Fe(III) chelator.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Hemoglobin (Hb) is a toxic molecule responsible for the extreme lethality associated with experimental Escherichia coli peritonitis, but the mechanism has yet to be elucidated." | 1.30 | Hemoglobin toxicity in experimental bacterial peritonitis is due to production of reactive oxygen species. ( Han, JA; Kim, KM; Kim, SS; Kim, YM; Lea, HZ; Yoo, YM, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (50.00) | 18.7374 |
| 1990's | 2 (25.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mike, LA | 1 |
| Tripathi, A | 1 |
| Blankenship, CM | 1 |
| Saluk, A | 1 |
| Schultz, PJ | 1 |
| Tamayo-Castillo, G | 1 |
| Sherman, DH | 1 |
| Mobley, HLT | 1 |
| Hod, EA | 1 |
| Zhang, N | 1 |
| Sokol, SA | 1 |
| Wojczyk, BS | 1 |
| Francis, RO | 1 |
| Ansaldi, D | 1 |
| Francis, KP | 1 |
| Della-Latta, P | 1 |
| Whittier, S | 1 |
| Sheth, S | 1 |
| Hendrickson, JE | 1 |
| Zimring, JC | 1 |
| Brittenham, GM | 1 |
| Spitalnik, SL | 1 |
| Gupta, R | 1 |
| Gupta, S | 1 |
| Joshi, K | 1 |
| Ganguly, NK | 1 |
| Yoo, YM | 1 |
| Kim, KM | 1 |
| Kim, SS | 1 |
| Han, JA | 1 |
| Lea, HZ | 1 |
| Kim, YM | 1 |
| Lee, JT | 1 |
| Ahrenholz, DH | 1 |
| Nelson, RD | 1 |
| Simmons, RL | 1 |
| Novotny, MJ | 1 |
| Laughlin, MH | 1 |
| Adams, HR | 1 |
| Fettman, MJ | 2 |
| Brooks, PA | 2 |
| Jones, RL | 1 |
| Mero, KN | 1 |
| Phillips, RW | 2 |
8 other studies available for deferoxamine and E coli Infections
| Article | Year |
|---|---|
Discovery of nicoyamycin A, an inhibitor of uropathogenic Escherichia coli growth in low iron environments.
Topics: Anti-Bacterial Agents; Biological Products; Deferoxamine; Dioxanes; Dose-Response Relationship, Drug | 2017 |
Transfusion of red blood cells after prolonged storage produces harmful effects that are mediated by iron and inflammation.
Topics: Acute-Phase Reaction; Animals; Blood Preservation; Deferoxamine; Disease Models, Animal; Endotoxemia | 2010 |
Role of iron and iron chelation therapy in oxygen free radical mediated tissue injury in an ascending mouse model of chronic pyelonephritis.
Topics: Animals; Chelation Therapy; Chronic Disease; Citric Acid; Deferoxamine; Disease Models, Animal; Drug | 1997 |
Hemoglobin toxicity in experimental bacterial peritonitis is due to production of reactive oxygen species.
Topics: Animals; Chelating Agents; Cyclic N-Oxides; Deferoxamine; Disease Models, Animal; Edetic Acid; Esche | 1999 |
Mechanisms of the adjuvant effect of hemoglobin in experimental peritonitis. V. The significance of the coordinated iron component.
Topics: Animals; Deferoxamine; Escherichia coli Infections; Ferric Compounds; Hematoporphyrins; Hemin; Hemog | 1979 |
Evidence for lack of importance of oxygen free radicals in Escherichia coli endotoxemia in dogs.
Topics: Animals; Cardiovascular System; Catalase; Deferoxamine; Dogs; Endotoxins; Escherichia coli Infection | 1988 |
Antimicrobial alternatives for calf diarrhea: enteric responses to Escherichia coli, deferoxamine, or gallium in neonatal calves.
Topics: Animals; Cattle; Cattle Diseases; Deferoxamine; Diarrhea; Escherichia coli Infections; Feces; Galliu | 1987 |
Antimicrobial alternatives for calf diarrhea: sera trace element responses to Escherichia coli-, deferoxamine-, or gallium-induced diarrhea.
Topics: Animals; Blood Glucose; Body Temperature; Cattle; Cattle Diseases; Copper; Deferoxamine; Diarrhea; E | 1987 |