Page last updated: 2024-10-25

deferoxamine and Dermatoses

deferoxamine has been researched along with Dermatoses in 22 studies

Deferoxamine: Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
desferrioxamine B : An acyclic desferrioxamine that is butanedioic acid in which one of the carboxy groups undergoes formal condensation with the primary amino group of N-(5-aminopentyl)-N-hydroxyacetamide and the second carboxy group undergoes formal condensation with the hydroxyamino group of N(1)-(5-aminopentyl)-N(1)-hydroxy-N(4)-[5-(hydroxyamino)pentyl]butanediamide. It is a siderophore native to Streptomyces pilosus biosynthesised by the DesABCD enzyme cluster as a high affinity Fe(III) chelator.

Research Excerpts

ExcerptRelevanceReference
"The purpose of the present work is to investigate the ability of desferrioxamine (DF) as an iron chelator to revert or decrease a severe experimental porphyria induced by hexachlorobenzene (HCB) in rats; DF treatment started after 17 weeks of HCB intoxication and was continued until the 27th week."7.67[Evaluation of deferoxamine capacity to revert a severe porphyria induced by hexachlorobenzene]. ( Aldonatti, CA; Billi, SC; San Martín de Viale, LC; Wainstok de Calmanovici, R, 1987)
"The present work deals with the effect of desferrioxamine (DF) on hexachlorobenzene (HCB)-induced porphyria in female rats with the purpose of further investigation of the role of iron in the development of this porphyria."7.67Effect of desferrioxamine on the development of hexachlorobenzene-induced porphyria. ( Aldonatti, CA; Billi, SC; San Martín de Viale, LC; Wainstock de Calmanovici, R, 1986)
"The purpose of the present work is to investigate the ability of desferrioxamine (DF) as an iron chelator to revert or decrease a severe experimental porphyria induced by hexachlorobenzene (HCB) in rats; DF treatment started after 17 weeks of HCB intoxication and was continued until the 27th week."3.67[Evaluation of deferoxamine capacity to revert a severe porphyria induced by hexachlorobenzene]. ( Aldonatti, CA; Billi, SC; San Martín de Viale, LC; Wainstok de Calmanovici, R, 1987)
"The present work deals with the effect of desferrioxamine (DF) on hexachlorobenzene (HCB)-induced porphyria in female rats with the purpose of further investigation of the role of iron in the development of this porphyria."3.67Effect of desferrioxamine on the development of hexachlorobenzene-induced porphyria. ( Aldonatti, CA; Billi, SC; San Martín de Viale, LC; Wainstock de Calmanovici, R, 1986)

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-199015 (68.18)18.7374
1990's5 (22.73)18.2507
2000's0 (0.00)29.6817
2010's2 (9.09)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kong, L1
Wu, Z1
Zhao, H1
Cui, H1
Shen, J1
Chang, J1
Li, H1
He, Y1
Yang, J1
Xia, Y1
Liu, X1
Jiang, S1
Xiong, L1
Marchesi, L1
Di Padova, C1
Cainelli, T1
Reseghetti, A1
Di Padova, F1
Rovagnati, P1
Cantoni, L1
Gibertini, P4
Rocchi, E6
Cassanelli, M6
Pietrangelo, A4
Ventura, E6
Halliday, JW1
Bassett, ML1
Piazza, V1
Villa, G1
Galli, F1
Segagni, S1
Bovio, G1
Poggio, F1
Picardi, L1
Bianco, L1
Salvadeo, A1
Barosi, G1
Toriyama, T1
Kawahara, H1
Borghi, A3
Paolillo, F1
Pradelli, M1
Pellizzardi, S1
Vezzosi, A1
Gallo, E1
Baccarani Contri, M1
Stockenhuber, F1
Kurz, R1
Grimm, G1
Moser, G1
Balcke, P1
Muñoz, JJ1
Garcia-Cabezas, J1
Martinez-Verano, J1
Perez-Oteyza, C1
Enriquez de Salamanca, R2
Wainstok de Calmanovici, R1
Billi, SC2
Aldonatti, CA2
San Martín de Viale, LC2
Pantaleoni, M1
Jensen, J1
Wainstock de Calmanovici, R1
Praga, M1
Andres, A1
Nieto, J1
Oliet, A1
Perpiña, J1
Morales, JM1
Gheorghiu, G1
Forsea, D1
Thivolet, J1
Bondet, P1
Perrot, H1
Moene, Y1
Horvat, Z1
Bakran, I1
Radosević, Z1
Duverne, J1
Brizard, CP1
Mounier, R1
Beurey, J1
Weber, M1
Gurecki, H1
Perello, R1
Vadot, J1

Trials

1 trial available for deferoxamine and Dermatoses

ArticleYear
A comparative trial of desferrioxamine and hydroxychloroquine for treatment of porphyria cutanea tarda in alcoholic patients.
    Photo-dermatology, 1984, Volume: 1, Issue:6

    Topics: Adult; Alcoholism; Clinical Trials as Topic; Deferoxamine; Ferritins; Humans; Hydroxychloroquine; Ir

1984

Other Studies

21 other studies available for deferoxamine and Dermatoses

ArticleYear
Bioactive Injectable Hydrogels Containing Desferrioxamine and Bioglass for Diabetic Wound Healing.
    ACS applied materials & interfaces, 2018, Sep-12, Volume: 10, Issue:36

    Topics: Ceramics; Deferoxamine; Diabetes Complications; Endothelial Cells; Gene Expression Regulation; Human

2018
Desferrioxamine shows different potentials for enhancing 5-aminolaevulinic acid-based photodynamic therapy in several cutaneous cell lines.
    Lasers in medical science, 2010, Volume: 25, Issue:2

    Topics: Aminolevulinic Acid; Cell Death; Cell Line; Deferoxamine; Drug Synergism; Fibroblasts; Humans; Iron

2010
Porphyria cutanea tarda in beta-thalassemia trait carriers.
    Dermatologica, 1984, Volume: 169, Issue:3

    Topics: Adult; Deferoxamine; Heterozygote; Humans; Liver Diseases; Male; Middle Aged; Porphyrias; Skin Disea

1984
Advances in the treatment of porphyria cutanea tarda. Effectiveness of slow subcutaneous desferrioxamine infusion.
    Liver, 1984, Volume: 4, Issue:4

    Topics: Adult; Aged; Deferoxamine; Humans; Infusions, Parenteral; Injections, Subcutaneous; Middle Aged; Por

1984
Treatment of iron storage disorders.
    Drugs, 1980, Volume: 20, Issue:3

    Topics: Anemia; Deferoxamine; Hemochromatosis; Humans; Iron; Liver Cirrhosis; Porphyrias; Skin Diseases; Tha

1980
Erythropoietin as treatment of haemodialysis-related porphyria cutanea tarda.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1992, Volume: 7, Issue:5

    Topics: Aged; Deferoxamine; Erythrocytes; Erythropoietin; Humans; Iron; Male; Porphyrias; Porphyrins; Protop

1992
[Small volume plasma exchange therapy in patients with porphyria cutanea tarda on maintenance hemodialysis].
    Nihon rinsho. Japanese journal of clinical medicine, 1992, Volume: 50 Suppl

    Topics: Deferoxamine; Erythropoietin; Humans; Kidney Diseases; Male; Middle Aged; Plasma Exchange; Porphyria

1992
Liver iron overload and desferrioxamine treatment of porphyria cutanea tarda.
    Dermatologica, 1991, Volume: 182, Issue:1

    Topics: Bloodletting; Chromatography, High Pressure Liquid; Chronic Disease; Deferoxamine; Ferritins; Humans

1991
Successful treatment of hemodialysis-related porphyria cutanea tarda with deferoxamine.
    Nephron, 1990, Volume: 55, Issue:3

    Topics: Deferoxamine; Female; Humans; Middle Aged; Porphyrias; Renal Dialysis; Skin Diseases

1990
Desferrioxamine in the treatment of porphyria cutanea tarda: ineffectiveness of intramuscular administration.
    The Journal of dermatology, 1990, Volume: 17, Issue:5

    Topics: Adult; Deferoxamine; Humans; Injections, Intramuscular; Male; Middle Aged; Porphyrias; Skin Diseases

1990
[Evaluation of deferoxamine capacity to revert a severe porphyria induced by hexachlorobenzene].
    Acta physiologica et pharmacologica latinoamericana : organo de la Asociacion Latinoamericana de Ciencias Fisiologicas y de la Asociacion Latinoamericana de Farmacologia, 1987, Volume: 37, Issue:4

    Topics: 5-Aminolevulinate Synthetase; Animals; Carboxy-Lyases; Deferoxamine; Hexachlorobenzene; Liver; Porph

1987
High weekly intravenous doses of desferrioxamine in porphyria cutanea tarda.
    The British journal of dermatology, 1987, Volume: 117, Issue:3

    Topics: Aged; Deferoxamine; Dose-Response Relationship, Drug; Humans; Infusions, Intravenous; Male; Middle A

1987
Iron removal therapy in porphyria cutanea tarda: phlebotomy versus slow subcutaneous desferrioxamine infusion.
    The British journal of dermatology, 1986, Volume: 114, Issue:5

    Topics: Adult; Bloodletting; Deferoxamine; Female; Humans; Infusions, Parenteral; Iron; Male; Middle Aged; P

1986
Effect of desferrioxamine on the development of hexachlorobenzene-induced porphyria.
    Biochemical pharmacology, 1986, Jul-15, Volume: 35, Issue:14

    Topics: 5-Aminolevulinate Synthetase; Animals; Body Weight; Carboxy-Lyases; Chlorobenzenes; Deferoxamine; Di

1986
Treatment of hemodialysis-related porphyria cutanea tarda with deferoxamine.
    The New England journal of medicine, 1987, Feb-26, Volume: 316, Issue:9

    Topics: Adult; Deferoxamine; Humans; Male; Porphyrias; Renal Dialysis; Skin Diseases

1987
Serum ferritin in the assessment of liver iron overload and iron removal therapy in porphyria cutanea tarda.
    The Journal of laboratory and clinical medicine, 1986, Volume: 107, Issue:1

    Topics: Adult; Deferoxamine; Female; Ferritins; Humans; Iron; Liver; Male; Middle Aged; Porphyrias; Skin Dis

1986
[Treatment of cutaneous porphyrias].
    Medicina interna, 1968, Volume: 20, Issue:11

    Topics: Adrenocorticotropic Hormone; Anabolic Agents; Deferoxamine; Edetic Acid; Humans; Porphyrias; Skin Di

1968
[Treatment of late cutaneous porphyrias with iron chelating agents (EDTA, Desferral)].
    Bulletin de la Societe francaise de dermatologie et de syphiligraphie, 1967, Volume: 74, Issue:3

    Topics: Adult; Deferoxamine; Edetic Acid; Humans; Male; Middle Aged; Porphyrias; Skin Diseases

1967
[Treatment of late cutaneous porphyria by desferal].
    Lijecnicki vjesnik, 1969, Volume: 91, Issue:2

    Topics: Deferoxamine; Female; Humans; Middle Aged; Porphyrias; Skin Diseases

1969
[Inveterate leg ulcer in a constitutional hemolytic syndrome with dermosiderosis. Cure by desfrrioxamine].
    Bulletin de la Societe francaise de dermatologie et de syphiligraphie, 1967, Volume: 74, Issue:4

    Topics: Adult; Deferoxamine; Humans; Leg Ulcer; Male; Siderosis; Skin Diseases; Thalassemia

1967
[Favorable clinical and biological action of iron chelator in 4 cases of porphyria cutanea tarda. Attempts at interpretation].
    Bulletin de la Societe francaise de dermatologie et de syphiligraphie, 1968, Volume: 75, Issue:5

    Topics: Adult; Aged; Alcoholism; Deferoxamine; Humans; Male; Porphyrias; Siderosis; Skin Diseases

1968