deferoxamine has been researched along with Cytomegalovirus in 6 studies
Deferoxamine: Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
desferrioxamine B : An acyclic desferrioxamine that is butanedioic acid in which one of the carboxy groups undergoes formal condensation with the primary amino group of N-(5-aminopentyl)-N-hydroxyacetamide and the second carboxy group undergoes formal condensation with the hydroxyamino group of N(1)-(5-aminopentyl)-N(1)-hydroxy-N(4)-[5-(hydroxyamino)pentyl]butanediamide. It is a siderophore native to Streptomyces pilosus biosynthesised by the DesABCD enzyme cluster as a high affinity Fe(III) chelator.
Cytomegalovirus: A genus of the family HERPESVIRIDAE, subfamily BETAHERPESVIRINAE, infecting the salivary glands, liver, spleen, lungs, eyes, and other organs, in which they produce characteristically enlarged cells with intranuclear inclusions. Infection with Cytomegalovirus is also seen as an opportunistic infection in AIDS.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cinatl, J | 9 |
| Rabenau, H | 4 |
| Gümbel, HO | 1 |
| Kornhuber, B | 1 |
| Doerr, HW | 5 |
| Gümbel, H | 1 |
| Vogel, JU | 1 |
| Ohrloff, C | 1 |
| Scholz, M | 4 |
| Weber, B | 2 |
| Markus, BH | 1 |
| Encke, A | 1 |
| Hoffmann, F | 1 |
| Stieneker, F | 1 |
| Kabickova, H | 1 |
| Blasko, M | 1 |
| Kloover, JS | 1 |
| Lautenschlager, I | 2 |
| Grauls, GE | 1 |
| Bruggeman, CA | 1 |
| Martelius, T | 1 |
| Krogerus, L | 1 |
| Höckerstedt, K | 1 |
| Loginov, R | 1 |
| Bruggeman, C | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Application of Iron Chelator (Desferal) to Reduce the Severity of COVID-19 Manifestations[NCT04333550] | Phase 1/Phase 2 | 50 participants (Anticipated) | Interventional | 2020-04-30 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
6 other studies available for deferoxamine and Cytomegalovirus
| Article | Year |
|---|---|
In vitro inhibition of human cytomegalovirus replication by desferrioxamine.
Topics: Cell Division; Cell Line; Cytomegalovirus; Deferoxamine; Fibroblasts; Humans; Iron; Viral Plaque Ass | 1994 |
[Selective inhibition of replication of human cytomegalovirus by desferrioxamine in vitro and in vivo (case report)].
Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cytomegalovirus; Cytomegalovirus Ret | 1995 |
Effects of desferrioxamine on human cytomegalovirus replication and expression of HLA antigens and adhesion molecules in human vascular endothelial cells.
Topics: Cell Adhesion Molecules; Cell Survival; Cells, Cultured; Cytomegalovirus; Deferoxamine; DNA; Endothe | 1995 |
In vitro inhibition of human cytomegalovirus replication by calcium trinatrium diethylenetriaminepentaacetic acid.
Topics: 2,2'-Dipyridyl; Antigens, Viral; Antiviral Agents; Cell Division; Cell Line; Cytomegalovirus; Defero | 1996 |
Effect of desferrioxamine (DFO) and calcium trinatrium diethylenetriaminepentaacetic acid (DTPA) on rat cytomegalovirus replication in vitro and in vivo.
Topics: Animals; Antigens, Viral; Antiviral Agents; Cells, Cultured; Cytomegalovirus; Cytomegalovirus Infect | 1999 |
Antiviral and immunomodulatory effects of desferrioxamine in cytomegalovirus-infected rat liver allografts with rejection.
Topics: Adjuvants, Immunologic; Animals; Antiviral Agents; Cell Adhesion Molecules; Cytomegalovirus; Cytomeg | 1999 |