deferoxamine has been researched along with Craniocerebral Trauma in 2 studies
Deferoxamine: Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
desferrioxamine B : An acyclic desferrioxamine that is butanedioic acid in which one of the carboxy groups undergoes formal condensation with the primary amino group of N-(5-aminopentyl)-N-hydroxyacetamide and the second carboxy group undergoes formal condensation with the hydroxyamino group of N(1)-(5-aminopentyl)-N(1)-hydroxy-N(4)-[5-(hydroxyamino)pentyl]butanediamide. It is a siderophore native to Streptomyces pilosus biosynthesised by the DesABCD enzyme cluster as a high affinity Fe(III) chelator.
Craniocerebral Trauma: Traumatic injuries involving the cranium and intracranial structures (i.e., BRAIN; CRANIAL NERVES; MENINGES; and other structures). Injuries may be classified by whether or not the skull is penetrated (i.e., penetrating vs. nonpenetrating) or whether there is an associated hemorrhage.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Dextran-DFO significantly decreased the incidence of severe neurologic impairment at dosage levels of 0." | 1.28 | Dextran-coupled deferoxamine improves outcome in a murine model of head injury. ( Braughler, JM; Hall, ED; Panter, SS, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jacobsen, EJ | 1 |
| McCall, JM | 1 |
| Ayer, DE | 1 |
| Van Doornik, FJ | 1 |
| Palmer, JR | 1 |
| Belonga, KL | 1 |
| Braughler, JM | 2 |
| Hall, ED | 2 |
| Houser, DJ | 1 |
| Krook, MA | 1 |
| Panter, SS | 1 |
2 other studies available for deferoxamine and Craniocerebral Trauma
| Article | Year |
|---|---|
Novel 21-aminosteroids that inhibit iron-dependent lipid peroxidation and protect against central nervous system trauma.
Topics: Amines; Animals; Antioxidants; Craniocerebral Trauma; Drug Evaluation, Preclinical; Lipid Peroxidati | 1990 |
Dextran-coupled deferoxamine improves outcome in a murine model of head injury.
Topics: Animals; Chelating Agents; Craniocerebral Trauma; Deferoxamine; Dextrans; Iron; Lipid Peroxidation; | 1992 |