deferoxamine has been researched along with Complications, Pregnancy in 14 studies
Deferoxamine: Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
desferrioxamine B : An acyclic desferrioxamine that is butanedioic acid in which one of the carboxy groups undergoes formal condensation with the primary amino group of N-(5-aminopentyl)-N-hydroxyacetamide and the second carboxy group undergoes formal condensation with the hydroxyamino group of N(1)-(5-aminopentyl)-N(1)-hydroxy-N(4)-[5-(hydroxyamino)pentyl]butanediamide. It is a siderophore native to Streptomyces pilosus biosynthesised by the DesABCD enzyme cluster as a high affinity Fe(III) chelator.
| Excerpt | Relevance | Reference |
|---|---|---|
| "An ovine model of maternal iron poisoning in pregnancy was used to examine the placental transport of deferoxamine and ferrioxamine and to follow maternal and fetal serum iron concentrations when maternal serum iron levels exceeded total iron-binding capacity." | 3.68 | An ovine model of maternal iron poisoning in pregnancy. ( Bond, GR; Curry, SC; Raschke, R; Tellez, D; Wiggins, D, 1990) |
| "Diabetes insipidus is a rare disorder in pregnant women, predating pregnancy or appearing for the first time during gestation." | 1.36 | Recurrent pregnancy-induced diabetes insipidus in a woman with hemochromatosis. ( Kobielusz-Gembala, I; Krysiak, R; Okopien, B, 2010) |
| "Its use during pregnancy has not been described for either indication." | 1.28 | Whole bowel irrigation during pregnancy. ( Tenenbein, M; Van Ameyde, KJ, 1989) |
| "Deferoxamine treatment was given with a delay of 26 hours after ingestion." | 1.27 | Fatal iron intoxication in late pregnancy. ( Biber, B; Dottori, O; Olenmark, M; Rybo, G, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (28.57) | 18.7374 |
| 1990's | 5 (35.71) | 18.2507 |
| 2000's | 4 (28.57) | 29.6817 |
| 2010's | 1 (7.14) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Krysiak, R | 1 |
| Kobielusz-Gembala, I | 1 |
| Okopien, B | 1 |
| Tsironi, M | 1 |
| Ladis, V | 1 |
| Margellis, Z | 1 |
| Deftereos, S | 1 |
| Kattamis, Ch | 1 |
| Aessopos, A | 1 |
| Madiwale, T | 1 |
| Liebelt, E | 1 |
| Blanc, P | 1 |
| Hryhorczuk, D | 1 |
| Danel, I | 1 |
| Khoury, S | 1 |
| Odeh, M | 1 |
| Oettinger, M | 1 |
| Turk, J | 1 |
| Aks, S | 1 |
| Ampuero, F | 1 |
| Hryhorczuk, DO | 1 |
| Tran, T | 1 |
| Wax, JR | 1 |
| Philput, C | 1 |
| Steinfeld, JD | 1 |
| Ingardia, CJ | 1 |
| Hung, TH | 1 |
| Skepper, JN | 1 |
| Burton, GJ | 1 |
| Strom, RL | 1 |
| Schiller, P | 1 |
| Seeds, AE | 1 |
| Bensel, RT | 1 |
| Lacoste, H | 1 |
| Goyert, GL | 1 |
| Goldman, LS | 1 |
| Wright, DJ | 1 |
| Schwartz, DB | 1 |
| McElhatton, PR | 1 |
| Roberts, JC | 1 |
| Sullivan, FM | 1 |
| Curry, SC | 1 |
| Bond, GR | 1 |
| Raschke, R | 1 |
| Tellez, D | 1 |
| Wiggins, D | 1 |
| Van Ameyde, KJ | 1 |
| Tenenbein, M | 1 |
| Olenmark, M | 1 |
| Biber, B | 1 |
| Dottori, O | 1 |
| Rybo, G | 1 |
3 reviews available for deferoxamine and Complications, Pregnancy
| Article | Year |
|---|---|
Iron: not a benign therapeutic drug.
Topics: Chelation Therapy; Child; Deferoxamine; Female; Humans; Iron; Liver; Poisoning; Pregnancy; Pregnancy | 2006 |
Intentional iron overdose in pregnancy--management and outcome.
Topics: Adolescent; Adult; Analysis of Variance; Chelating Agents; Deferoxamine; Drug Overdose; Emergency Se | 2000 |
Acute iron intoxication in pregnancy: case report and review of the literature.
Topics: Adolescent; Deferoxamine; Delayed-Action Preparations; Female; Ferrous Compounds; Humans; Poisoning; | 1992 |
11 other studies available for deferoxamine and Complications, Pregnancy
| Article | Year |
|---|---|
Recurrent pregnancy-induced diabetes insipidus in a woman with hemochromatosis.
Topics: Adult; Biopsy, Needle; Cystinyl Aminopeptidase; Deferoxamine; Diabetes Insipidus; Female; Hemochroma | 2010 |
Impairment of cardiac function in a successful full-term pregnancy in a homozygous beta-thalassemia major: does chelation have a positive role?
Topics: Adult; beta-Thalassemia; Deferoxamine; Female; Heart Diseases; Humans; Iron Chelating Agents; Pregna | 2005 |
Deferoxamine treatment of acute iron intoxication in pregnancy.
Topics: Abortion, Induced; Adolescent; Deferoxamine; Female; Ferric Compounds; Humans; Ipecac; Iron; Pregnan | 1984 |
Deferoxamine treatment for acute iron intoxication in pregnancy.
Topics: Adult; Antidotes; Deferoxamine; Female; Ferrous Compounds; Humans; Injections, Intravenous; Iron; Pr | 1995 |
Successful therapy of iron intoxication in pregnancy with intravenous deferoxamine and whole bowel irrigation.
Topics: Adult; Deferoxamine; Female; Humans; Infusions, Intravenous; Intestines; Iron; Pregnancy; Pregnancy | 1993 |
In vitro ischemia-reperfusion injury in term human placenta as a model for oxidative stress in pathological pregnancies.
Topics: Aldehydes; Cyclic N-Oxides; Deferoxamine; Female; Fluorescent Antibody Technique; Heat-Shock Protein | 2001 |
Fatal iron poisoning in a pregnant female.
Topics: Acute Disease; Adolescent; Deferoxamine; Female; Gastrointestinal Hemorrhage; Humans; Iron; Liver; P | 1976 |
The consequences of iron overdose and its treatment with desferrioxamine in pregnancy.
Topics: Birth Weight; Deferoxamine; Drug Overdose; Female; Humans; Infant, Newborn; Iron; Male; Pregnancy; P | 1991 |
An ovine model of maternal iron poisoning in pregnancy.
Topics: Animals; Blood Pressure; Body Weight; Deferoxamine; Disease Models, Animal; Female; Ferric Compounds | 1990 |
Whole bowel irrigation during pregnancy.
Topics: Adolescent; Deferoxamine; Digestive System; Female; Humans; Iron; Pregnancy; Pregnancy Complications | 1989 |
Fatal iron intoxication in late pregnancy.
Topics: Adult; Cesarean Section; Deferoxamine; Delayed-Action Preparations; Female; Ferrous Compounds; Human | 1987 |