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deferoxamine and Complications, Hematologic Pregnancy

deferoxamine has been researched along with Complications, Hematologic Pregnancy in 17 studies

Deferoxamine: Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
desferrioxamine B : An acyclic desferrioxamine that is butanedioic acid in which one of the carboxy groups undergoes formal condensation with the primary amino group of N-(5-aminopentyl)-N-hydroxyacetamide and the second carboxy group undergoes formal condensation with the hydroxyamino group of N(1)-(5-aminopentyl)-N(1)-hydroxy-N(4)-[5-(hydroxyamino)pentyl]butanediamide. It is a siderophore native to Streptomyces pilosus biosynthesised by the DesABCD enzyme cluster as a high affinity Fe(III) chelator.

Research Excerpts

ExcerptRelevanceReference
"In this retrospective cohort study, we described the evolution and outcome of 9 pregnancies in Italian thalassemic women who received deferoxamine (DFO) inadvertently during early pregnancy."7.96Use of deferoxamine (DFO) in transfusion-dependent β-thalassemia during pregnancy: A retrospective study. ( Brunelli, R; Capone, C; D'Ambrosio, V; Del Negro, V; Giancotti, A; Piccioni, MG; Schiavi, MC; Smacchia, MP; Vena, F, 2020)
"In our study, chelation treatment during pregnancy did not prevent the delivery of healthy children."5.43Iron chelation therapy of transfusion-dependent β-thalassemia during pregnancy in the era of novel drugs: is deferasirox toxic? ( Agapidou, A; Diamantidis, MD; Fotiou, P; Manafas, A; Neokleous, N; Vetsiou, E; Vlachaki, E, 2016)
"In this retrospective cohort study, we described the evolution and outcome of 9 pregnancies in Italian thalassemic women who received deferoxamine (DFO) inadvertently during early pregnancy."3.96Use of deferoxamine (DFO) in transfusion-dependent β-thalassemia during pregnancy: A retrospective study. ( Brunelli, R; Capone, C; D'Ambrosio, V; Del Negro, V; Giancotti, A; Piccioni, MG; Schiavi, MC; Smacchia, MP; Vena, F, 2020)
"In our study, chelation treatment during pregnancy did not prevent the delivery of healthy children."1.43Iron chelation therapy of transfusion-dependent β-thalassemia during pregnancy in the era of novel drugs: is deferasirox toxic? ( Agapidou, A; Diamantidis, MD; Fotiou, P; Manafas, A; Neokleous, N; Vetsiou, E; Vlachaki, E, 2016)
"Deferoxamine therapy was continued throughout 2 pregnancies, while in the other it was stopped after 8 weeks: no abnormalities were noted in the children."1.31High-risk pregnancy in beta-thalassemia major women. Report of three cases. ( De Marzi, CA; Magliari, F; Perniola, R; Rosatelli, MC, 2000)
"The twin-pregnancy was complicated by preeclampsia."1.30Pregnancy and lactation in homozygous beta-thalassemia major. ( Glanzmann, R; Holzgreve, W; Nars, PW; Surbek, DV, 1998)
"Pregnancy was well tolerated by the heart in all women and no endocrinological disorders were observed."1.30Fertility in thalassemia: the Greek experience. ( Karagiorga-Lagana, M, 1998)
"Successful pregnancy is described in a patient with beta-thalassaemia major, transfusion-dependent from four months of age and treated with desferrioxamine from 13 years of age."1.27Successful pregnancy in beta-thalassaemia major. ( Martin, K, 1983)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19905 (29.41)18.7374
1990's4 (23.53)18.2507
2000's5 (29.41)29.6817
2010's2 (11.76)24.3611
2020's1 (5.88)2.80

Authors

AuthorsStudies
Piccioni, MG1
Capone, C1
Vena, F1
Del Negro, V1
Schiavi, MC1
D'Ambrosio, V1
Giancotti, A1
Smacchia, MP1
Brunelli, R1
Diamantidis, MD1
Neokleous, N1
Agapidou, A1
Vetsiou, E1
Manafas, A1
Fotiou, P1
Vlachaki, E1
Shetty, A1
Anwar, SQ1
Acharya, S1
Sözen, M1
Karaaslan, C1
Oner, R1
Gümrük, F1
Ozdemir, MA1
Altay, C1
Gürgey, A1
Oner, C1
Beneitez, D1
Casellas, M1
Carrera, A1
Duran-Suárez, JR1
Martin, K1
Meadows, K1
Dolfin, G1
Lumare, A1
Tinetti, E1
Monetti, C1
Jacob, R1
Martoglio, G1
Thomas, RM1
Skalicka, AE1
Fistarol, M1
Zardini, E1
Surbek, DV1
Glanzmann, R1
Nars, PW1
Holzgreve, W1
Singer, ST1
Vichinsky, EP1
Karagiorga-Lagana, M1
Perniola, R1
Magliari, F1
Rosatelli, MC1
De Marzi, CA1
Pafumi, C1
Zizza, G1
Caruso, S1
Todaro, AM1
Pernicone, G1
Bandiera, S1
Farina, M1
Russo, A1
Palagiano, A1
Pace, L1
Stacher, A1

Reviews

1 review available for deferoxamine and Complications, Hematologic Pregnancy

ArticleYear
[Diseases caused by iron metabolism disorders and their therapy].
    Wiener Zeitschrift fur innere Medizin und ihre Grenzgebiete, 1969, Volume: 50, Issue:3

    Topics: Adult; Anemia, Hypochromic; Anti-Glomerular Basement Membrane Disease; Bloodletting; Deferoxamine; D

1969

Other Studies

16 other studies available for deferoxamine and Complications, Hematologic Pregnancy

ArticleYear
Use of deferoxamine (DFO) in transfusion-dependent β-thalassemia during pregnancy: A retrospective study.
    Taiwanese journal of obstetrics & gynecology, 2020, Volume: 59, Issue:1

    Topics: Adult; beta-Thalassemia; Chelation Therapy; Deferoxamine; Female; Humans; Live Birth; Maternal Expos

2020
Iron chelation therapy of transfusion-dependent β-thalassemia during pregnancy in the era of novel drugs: is deferasirox toxic?
    International journal of hematology, 2016, Volume: 103, Issue:5

    Topics: Adult; Benzoates; beta-Thalassemia; Chelation Therapy; Deferasirox; Deferiprone; Deferoxamine; Femal

2016
Aplastic anaemia in pregnancy.
    Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology, 2011, Volume: 31, Issue:1

    Topics: Anemia, Aplastic; Combined Modality Therapy; Deferoxamine; Female; Humans; Platelet Transfusion; Pre

2011
Severe hemolytic anemia associated with Hb Volga [beta27(B9)Ala-->Asp]: GCC-->GAC at codon 27 in a Turkish family.
    American journal of hematology, 2004, Volume: 76, Issue:4

    Topics: Adult; Anemia, Hemolytic, Congenital; Blood Protein Electrophoresis; Child, Preschool; Codon; Combin

2004
[Beta-thalassemia major and pregnancy to term].
    Medicina clinica, 2008, Feb-23, Volume: 130, Issue:6

    Topics: Adult; beta-Thalassemia; Deferoxamine; Female; Follow-Up Studies; Humans; Pregnancy; Pregnancy Compl

2008
Successful pregnancy in beta-thalassaemia major.
    Australian paediatric journal, 1983, Volume: 19, Issue:3

    Topics: Adult; Blood Transfusion; Deferoxamine; Female; Glucose; Humans; Hypoglycemia; Infant, Newborn; Infa

1983
A successful pregnancy outcome in transfusion dependent thalassaemia major.
    The Australian & New Zealand journal of obstetrics & gynaecology, 1984, Volume: 24, Issue:1

    Topics: Adult; Blood Transfusion; Deferoxamine; Erythrocyte Transfusion; Female; Humans; Infant, Newborn; Ma

1984
[Obstetrical and hematological problems in a pregnant woman with intermediate beta-thalassemia].
    Minerva ginecologica, 1983, Volume: 35, Issue:4

    Topics: Adult; Blood Transfusion; Deferoxamine; Female; Humans; Pregnancy; Pregnancy Complications, Hematolo

1983
Successful pregnancy in transfusion-dependent thalassaemia.
    Archives of disease in childhood, 1980, Volume: 55, Issue:7

    Topics: Adult; Blood Transfusion; Deferoxamine; Female; Humans; Infant, Newborn; Pregnancy; Pregnancy Compli

1980
[Beta-thalassemia and pregnancy: 2 rare cases].
    Gynakologisch-geburtshilfliche Rundschau, 1996, Volume: 36, Issue:1

    Topics: beta-Thalassemia; Bone Marrow Transplantation; Cardiotocography; Cesarean Section; Combined Modality

1996
Pregnancy and lactation in homozygous beta-thalassemia major.
    Journal of perinatal medicine, 1998, Volume: 26, Issue:3

    Topics: Adult; beta-Thalassemia; Breast Feeding; Chelating Agents; Deferoxamine; Female; Homozygote; Humans;

1998
Deferoxamine treatment during pregnancy: is it harmful?
    American journal of hematology, 1999, Volume: 60, Issue:1

    Topics: Abnormalities, Drug-Induced; Adult; Chelating Agents; Deferoxamine; Female; Humans; Pregnancy; Pregn

1999
Fertility in thalassemia: the Greek experience.
    Journal of pediatric endocrinology & metabolism : JPEM, 1998, Volume: 11 Suppl 3

    Topics: Adult; beta-Thalassemia; Cesarean Section; Chelating Agents; Deferoxamine; Endocrine Glands; Female;

1998
High-risk pregnancy in beta-thalassemia major women. Report of three cases.
    Gynecologic and obstetric investigation, 2000, Volume: 49, Issue:2

    Topics: Adult; Aspirin; beta-Thalassemia; Cardiomyopathy, Dilated; Deferoxamine; Female; Humans; Pregnancy;

2000
Pregnancy outcome of a transfusion-dependent thalassemic woman.
    Annals of hematology, 2000, Volume: 79, Issue:10

    Topics: Blood Transfusion; Chelating Agents; Deferoxamine; Female; Ferritins; Humans; Pregnancy; Pregnancy C

2000
[Pregnancy in women with thalassaemia].
    Minerva ginecologica, 2001, Volume: 53, Issue:3

    Topics: Adult; Blood Transfusion; Chelating Agents; Deferoxamine; Female; Folic Acid; Hematinics; Humans; In

2001