Compounds > deferoxamine
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deferoxamine and Complication, Postoperative

deferoxamine has been researched along with Complication, Postoperative in 12 studies

Deferoxamine: Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
desferrioxamine B : An acyclic desferrioxamine that is butanedioic acid in which one of the carboxy groups undergoes formal condensation with the primary amino group of N-(5-aminopentyl)-N-hydroxyacetamide and the second carboxy group undergoes formal condensation with the hydroxyamino group of N(1)-(5-aminopentyl)-N(1)-hydroxy-N(4)-[5-(hydroxyamino)pentyl]butanediamide. It is a siderophore native to Streptomyces pilosus biosynthesised by the DesABCD enzyme cluster as a high affinity Fe(III) chelator.

Research Excerpts

ExcerptRelevanceReference
"Flap necrosis was assessed on postoperative day 5."1.27A free radical scavenger reduces hematoma-induced flap necrosis in Fischer rats. ( Abramson, M; Angel, MF; Haddad, J, 1987)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19904 (33.33)18.7374
1990's4 (33.33)18.2507
2000's2 (16.67)29.6817
2010's2 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Pan, K2
Li, X2
Chen, Y1
Zhu, D1
Li, Y2
Tao, G2
Zuo, Z1
Chen, L1
Ning, JL1
Yang, T1
Terrando, N1
Gu, J1
HENDERSON, F1
VIETTI, TJ1
BROWN, EB1
Gaziev, J1
Sodani, P1
Polchi, P1
Andreani, M1
Lucarelli, G1
Soybir, G1
Köksoy, F1
Ekiz, F1
Yalçin, O1
Ozşeker, A1
Cokneşeli, B1
Nicholas, JC1
Dawes, PT1
Davies, SJ1
Freemont, AJ1
Ghosh, K1
Daar, S1
Hiwase, D1
Nursat, N1
Pearson, HA1
O'Brien, RT1
Qayumi, AK1
Janusz, MT1
Jamieson, WR1
Lyster, DM1
Wens, R1
Devriendt, J1
Collart, F1
Dratwa, M1
Bisschop, P1
Telerman-Toppet, N1
Douat, N1
Angel, MF1
Haddad, J1
Abramson, M1
Smetana, S1
Popovtzer, MM1
Bar-Khayim, Y1

Other Studies

12 other studies available for deferoxamine and Complication, Postoperative

ArticleYear
Deferoxamine pre-treatment protects against postoperative cognitive dysfunction of aged rats by depressing microglial activation via ameliorating iron accumulation in hippocampus.
    Neuropharmacology, 2016, Volume: 111

    Topics: Animals; Apoptosis; Cation Transport Proteins; Cognitive Dysfunction; Deferoxamine; Hippocampus; Iro

2016
Deferoxamine regulates neuroinflammation and iron homeostasis in a mouse model of postoperative cognitive dysfunction.
    Journal of neuroinflammation, 2016, 10-12, Volume: 13, Issue:1

    Topics: Animals; Cell Line, Transformed; Cognition Disorders; Conditioning, Psychological; Deferoxamine; Dis

2016
DESFERRIOXAMINE IN THE TREATMENT OF ACUTE TOXIC REACTION TO FERROUS GLUCONATE.
    JAMA, 1963, Dec-28, Volume: 186

    Topics: Chelating Agents; Deferoxamine; Ferrous Compounds; Gluconates; Humans; Infant; Injections; Injection

1963
Bone marrow transplantation in adults with thalassemia: Treatment and long-term follow-up.
    Annals of the New York Academy of Sciences, 2005, Volume: 1054

    Topics: Adolescent; Adult; Azathioprine; Bone Marrow Transplantation; Busulfan; Chelation Therapy; Clinical

2005
Effect of mangan-desferrioxamin in the prevention of peritoneal adhesions.
    Journal of the Royal College of Surgeons of Edinburgh, 1998, Volume: 43, Issue:1

    Topics: Animals; Deferoxamine; Free Radical Scavengers; Laparotomy; Male; Manganese; Organometallic Compound

1998
Persisting aluminium-related bone disease after cadaveric renal transplantation.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1999, Volume: 14, Issue:1

    Topics: Aluminum Hydroxide; Biopsy; Bone and Bones; Bone Diseases; Cadaver; Chelating Agents; Deferoxamine;

1999
Primary pseudomonas meningitis in an adult, splenectomized, multitransfused thalassaemia major patient.
    Haematologia, 2000, Volume: 30, Issue:1

    Topics: Adolescent; Adult; Aged; beta-Thalassemia; Blood Transfusion; Chelating Agents; Chelation Therapy; C

2000
The management of thalassemia major.
    Seminars in hematology, 1975, Volume: 12, Issue:3

    Topics: Adolescent; Adult; Blood Transfusion; Chelating Agents; Child; Child, Preschool; Deferoxamine; Diet

1975
Pharmacologic interventions for prevention of spinal cord injury caused by aortic crossclamping.
    The Journal of thoracic and cardiovascular surgery, 1992, Volume: 104, Issue:2

    Topics: Allopurinol; Animals; Aorta; Aortic Aneurysm; Constriction; Deferoxamine; Free Radicals; Paraplegia;

1992
Rhinocerebral mucormycosis in haemodialysis patients treated with desferrioxamine: possible role of recent surgery as an additional risk factor.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1991, Volume: 6, Issue:9

    Topics: Amphotericin B; Brain Diseases; Deferoxamine; Humans; Male; Middle Aged; Mucormycosis; Nasal Mucosa;

1991
A free radical scavenger reduces hematoma-induced flap necrosis in Fischer rats.
    Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 1987, Volume: 96, Issue:1

    Topics: Animals; Deferoxamine; Graft Survival; Hematoma; Male; Necrosis; Postoperative Complications; Rats;

1987
[Aluminum-induced osteomalacia in chronic hemodialysis].
    Harefuah, 1987, Jun-15, Volume: 112, Issue:12

    Topics: Aluminum; Child, Preschool; Deferoxamine; Female; Humans; Osteomalacia; Parathyroid Glands; Postoper

1987