deferoxamine has been researched along with Color Vision Defects in 2 studies
Deferoxamine: Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
desferrioxamine B : An acyclic desferrioxamine that is butanedioic acid in which one of the carboxy groups undergoes formal condensation with the primary amino group of N-(5-aminopentyl)-N-hydroxyacetamide and the second carboxy group undergoes formal condensation with the hydroxyamino group of N(1)-(5-aminopentyl)-N(1)-hydroxy-N(4)-[5-(hydroxyamino)pentyl]butanediamide. It is a siderophore native to Streptomyces pilosus biosynthesised by the DesABCD enzyme cluster as a high affinity Fe(III) chelator.
Color Vision Defects: Defects of color vision are mainly hereditary traits but can be secondary to acquired or developmental abnormalities in the CONES (RETINA). Severity of hereditary defects of color vision depends on the degree of mutation of the ROD OPSINS genes (on X CHROMOSOME and CHROMOSOME 3) that code the photopigments for red, green and blue.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Of 89 patients receiving nightly subcutaneous deferoxamine for transfusion-dependent thalassemia major or Diamond-Blackfan anemia, 13 presented with visual loss or deafness of acute onset or both." | 3.67 | Visual and auditory neurotoxicity in patients receiving subcutaneous deferoxamine infusions. ( Buncic, JR; Chew, E; Gallant, T; Harrison, RV; Keenan, N; Logan, W; Mitchell, D; Olivieri, NF; Ricci, G; Skarf, B, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mehta, AM | 1 |
| Engstrom, RE | 1 |
| Kreiger, AE | 1 |
| Olivieri, NF | 1 |
| Buncic, JR | 1 |
| Chew, E | 1 |
| Gallant, T | 1 |
| Harrison, RV | 1 |
| Keenan, N | 1 |
| Logan, W | 1 |
| Mitchell, D | 1 |
| Ricci, G | 1 |
| Skarf, B | 1 |
2 other studies available for deferoxamine and Color Vision Defects
| Article | Year |
|---|---|
Deferoxamine-associated retinopathy after subcutaneous injection.
Topics: Aged; Anemia, Refractory; Color Vision Defects; Deferoxamine; Female; Fluorescein Angiography; Fundu | 1994 |
Visual and auditory neurotoxicity in patients receiving subcutaneous deferoxamine infusions.
Topics: Adolescent; Adult; Age Factors; Anemia, Aplastic; Audiometry; Child; Child, Preschool; Color Vision | 1986 |