deferoxamine has been researched along with Cicatrix in 2 studies
Deferoxamine: Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
desferrioxamine B : An acyclic desferrioxamine that is butanedioic acid in which one of the carboxy groups undergoes formal condensation with the primary amino group of N-(5-aminopentyl)-N-hydroxyacetamide and the second carboxy group undergoes formal condensation with the hydroxyamino group of N(1)-(5-aminopentyl)-N(1)-hydroxy-N(4)-[5-(hydroxyamino)pentyl]butanediamide. It is a siderophore native to Streptomyces pilosus biosynthesised by the DesABCD enzyme cluster as a high affinity Fe(III) chelator.
Cicatrix: The fibrous tissue that replaces normal tissue during the process of WOUND HEALING.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Deferoxamine treatment presents a potential therapeutic avenue through which to target impaired wound healing in patients following radiotherapy." | 1.72 | Transdermal deferoxamine administration improves excisional wound healing in chronically irradiated murine skin. ( Abbas, DB; Churukian, A; Griffin, M; Guardino, N; Guo, JL; Gurtner, GC; Lavin, CV; Lintel, H; Longaker, MT; Momeni, A; Wan, DC, 2022) |
| "Lesion-induced scarring is a major impediment for regeneration of injured axons in the central nervous system (CNS)." | 1.42 | Pharmacological Suppression of CNS Scarring by Deferoxamine Reduces Lesion Volume and Increases Regeneration in an In Vitro Model for Astroglial-Fibrotic Scarring and in Rat Spinal Cord Injury In Vivo. ( Brazda, N; Estrada, V; Faissner, A; König, B; Krafft, S; Müller, HW; Vogelaar, CF; Ziegler, B, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lintel, H | 1 |
| Abbas, DB | 1 |
| Lavin, CV | 1 |
| Griffin, M | 1 |
| Guo, JL | 1 |
| Guardino, N | 1 |
| Churukian, A | 1 |
| Gurtner, GC | 1 |
| Momeni, A | 1 |
| Longaker, MT | 1 |
| Wan, DC | 1 |
| Vogelaar, CF | 1 |
| König, B | 1 |
| Krafft, S | 1 |
| Estrada, V | 1 |
| Brazda, N | 1 |
| Ziegler, B | 1 |
| Faissner, A | 1 |
| Müller, HW | 1 |
2 other studies available for deferoxamine and Cicatrix
| Article | Year |
|---|---|
Transdermal deferoxamine administration improves excisional wound healing in chronically irradiated murine skin.
Topics: Animals; Cicatrix; Collagen; Deferoxamine; Humans; Mice; Nitric Oxide; Radiation Injuries; Skin; Wou | 2022 |
Pharmacological Suppression of CNS Scarring by Deferoxamine Reduces Lesion Volume and Increases Regeneration in an In Vitro Model for Astroglial-Fibrotic Scarring and in Rat Spinal Cord Injury In Vivo.
Topics: Animals; Astrocytes; Axons; Central Nervous System; Cicatrix; Collagen Type IV; Cyclic AMP; Deferoxa | 2015 |