deferoxamine has been researched along with Chronic Progressive Multiple Sclerosis in 1 studies
Deferoxamine: Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
desferrioxamine B : An acyclic desferrioxamine that is butanedioic acid in which one of the carboxy groups undergoes formal condensation with the primary amino group of N-(5-aminopentyl)-N-hydroxyacetamide and the second carboxy group undergoes formal condensation with the hydroxyamino group of N(1)-(5-aminopentyl)-N(1)-hydroxy-N(4)-[5-(hydroxyamino)pentyl]butanediamide. It is a siderophore native to Streptomyces pilosus biosynthesised by the DesABCD enzyme cluster as a high affinity Fe(III) chelator.
Excerpt | Relevance | Reference |
---|---|---|
" These results suggest that, while the drug is well tolerated, no effect on disease progression can be identified at this dosage level." | 2.69 | A multiple course trial of desferrioxamine in chronic progressive multiple sclerosis. ( Fonseca, T; LeVine, SM; Lynch, SG, 2000) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 1 (100.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Lynch, SG | 1 |
Fonseca, T | 1 |
LeVine, SM | 1 |
1 trial available for deferoxamine and Chronic Progressive Multiple Sclerosis
Article | Year |
---|---|
A multiple course trial of desferrioxamine in chronic progressive multiple sclerosis.
Topics: Adult; Deferoxamine; Disease Progression; Female; Humans; Iron Chelating Agents; Magnetic Resonance | 2000 |