deferoxamine has been researched along with Cataract, Membranous in 15 studies
Deferoxamine: Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
desferrioxamine B : An acyclic desferrioxamine that is butanedioic acid in which one of the carboxy groups undergoes formal condensation with the primary amino group of N-(5-aminopentyl)-N-hydroxyacetamide and the second carboxy group undergoes formal condensation with the hydroxyamino group of N(1)-(5-aminopentyl)-N(1)-hydroxy-N(4)-[5-(hydroxyamino)pentyl]butanediamide. It is a siderophore native to Streptomyces pilosus biosynthesised by the DesABCD enzyme cluster as a high affinity Fe(III) chelator.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To test whether iron accumulation in the lens following cigarette smoke exposure is the principal mechanism in smoke-related cataractogenesis and to assess the possible protective effect of deferoxamine mesylate treatment against lenticular degeneration with in vivo exposure to cigarette smoke." | 7.70 | Cataractous changes in rat lens following cigarette smoke exposure is prevented by parenteral deferoxamine therapy. ( Avunduk, AM; Avunduk, MC; Kurnaz, L; Yardimci, S, 1999) |
| "A single subcutaneous dose of 30 nmol of sodium selenite per gram of body weight in 13-day-old rats resulted in posterior subcapsular cataract (PSC) after 24 hr and bilateral nuclear cataracts at 72-96 hr." | 7.68 | Deferoxamine effect on selenite-induced cataract formation in rats. ( Bunce, GE; Hess, JL; Wang, Z, 1992) |
| "To test whether iron accumulation in the lens following cigarette smoke exposure is the principal mechanism in smoke-related cataractogenesis and to assess the possible protective effect of deferoxamine mesylate treatment against lenticular degeneration with in vivo exposure to cigarette smoke." | 3.70 | Cataractous changes in rat lens following cigarette smoke exposure is prevented by parenteral deferoxamine therapy. ( Avunduk, AM; Avunduk, MC; Kurnaz, L; Yardimci, S, 1999) |
| "A single subcutaneous dose of 30 nmol of sodium selenite per gram of body weight in 13-day-old rats resulted in posterior subcapsular cataract (PSC) after 24 hr and bilateral nuclear cataracts at 72-96 hr." | 3.68 | Deferoxamine effect on selenite-induced cataract formation in rats. ( Bunce, GE; Hess, JL; Wang, Z, 1992) |
| "Lens opacities were presented in 14 patients--22%." | 1.30 | [The mechanism of cataract formation in persons with beta-thalassemia]. ( Padakis, A; Popescu, C; Siganos, D; Zanakis, E, 1998) |
| "Amiodarone hydrochloride is a benzofurane derivative used to combat cardiac arrhythmia since 1960." | 1.27 | [Cataracts]. ( Hachet, E, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (46.67) | 18.7374 |
| 1990's | 6 (40.00) | 18.2507 |
| 2000's | 2 (13.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Schaal, S | 2 |
| Beiran, I | 2 |
| Bormusov, E | 1 |
| Chevion, M | 2 |
| Dovrat, A | 2 |
| Rozner, H | 1 |
| Rubinstein, I | 1 |
| Miller, B | 1 |
| Davies, SC | 1 |
| Marcus, RE | 1 |
| Hungerford, JL | 1 |
| Miller, MH | 1 |
| Arden, GB | 1 |
| Huehns, ER | 1 |
| Rinaldi, M | 1 |
| Della Corte, M | 1 |
| Ruocco, V | 1 |
| D'Onofrio, C | 1 |
| Zanotta, G | 1 |
| Romano, A | 1 |
| Popescu, C | 1 |
| Siganos, D | 1 |
| Zanakis, E | 1 |
| Padakis, A | 1 |
| Avunduk, AM | 1 |
| Yardimci, S | 1 |
| Avunduk, MC | 1 |
| Kurnaz, L | 1 |
| Wang, Z | 1 |
| Hess, JL | 1 |
| Bunce, GE | 1 |
| Bhuyan, KC | 1 |
| Bhuyan, DK | 1 |
| Chiu, W | 1 |
| Malik, S | 1 |
| Fridovich, I | 1 |
| Sorcinelli, R | 1 |
| Sitzia, A | 1 |
| Figus, A | 1 |
| Lai, ME | 1 |
| Caballero, LG | 1 |
| Schindléry, C | 1 |
| Freedman, MH | 1 |
| Bentur, Y | 1 |
| Koren, G | 1 |
| Hachet, E | 1 |
| Brückner, R | 1 |
| Hess, R | 1 |
| Keberle, H | 1 |
| Pericin, C | 1 |
| Tripod, J | 1 |
| Diwany, M | 1 |
| Gabr, M | 1 |
| el Hefni, A | 1 |
| Mokhtar, N | 1 |
2 reviews available for deferoxamine and Cataract, Membranous
| Article | Year |
|---|---|
[Auditory, visual and neurologic toxicity of deferoxamine].
Topics: Adolescent; Cataract; Deferoxamine; Hearing Loss, Sensorineural; Humans; Male; Middle Aged | 1989 |
Biological and toxic properties of deferoxamine.
Topics: Cataract; Cell Division; Deferoxamine; DNA; Drug Hypersensitivity; Hearing Disorders; Humans; Pulmon | 1989 |
13 other studies available for deferoxamine and Cataract, Membranous
| Article | Year |
|---|---|
Zinc-desferrioxamine reduces damage to lenses exposed to hyperbaric oxygen and has an ameliorative effect on catalase and Na, K-ATPase activities.
Topics: Animals; Antioxidants; Catalase; Cataract; Cattle; Deferoxamine; Histocytochemistry; Hyperbaric Oxyg | 2007 |
Desferrioxamine and zinc-desferrioxamine reduce lens oxidative damage.
Topics: Animals; Antioxidants; Cataract; Cattle; Deferoxamine; Histocytochemistry; Hyperbaric Oxygenation; I | 2007 |
Ocular toxicity of high-dose intravenous desferrioxamine.
Topics: Adolescent; Adult; Cataract; Child; Child, Preschool; Dark Adaptation; Deferoxamine; Female; Follow- | 1983 |
Ocular involvement correlated with age in patients affected by major and intermedia beta-thalassemia treated or not with desferrioxamine.
Topics: Adolescent; Adult; Age Factors; Angioid Streaks; beta-Thalassemia; Cataract; Child; Child, Preschool | 1993 |
[The mechanism of cataract formation in persons with beta-thalassemia].
Topics: Adolescent; Adult; beta-Thalassemia; Blood Transfusion; Cataract; Child; Corneal Opacity; Deferoxami | 1998 |
Cataractous changes in rat lens following cigarette smoke exposure is prevented by parenteral deferoxamine therapy.
Topics: Animals; Calcium; Cataract; Deferoxamine; Infusions, Parenteral; Iron; Iron Chelating Agents; Lens, | 1999 |
Deferoxamine effect on selenite-induced cataract formation in rats.
Topics: Animals; Body Weight; Calcium; Cataract; Deferoxamine; Disease Models, Animal; Glutathione; Injectio | 1992 |
Desferal-Mn(III) in the therapy of diquat-induced cataract in rabbit.
Topics: Animals; Ascorbic Acid; Cataract; Deferoxamine; Diquat; Free Radicals; Glutathione; Hydrogen Peroxid | 1991 |
Ocular findings in beta-thalassemia.
Topics: Adolescent; Adult; Blood Transfusion; Cataract; Child; Deferoxamine; Eye Diseases; Female; Humans; M | 1990 |
Acute visual and auditory neurotoxicity in patients with end-stage renal disease receiving desferrioxamine.
Topics: Cataract; Deferoxamine; Humans | 1989 |
[Cataracts].
Topics: Adrenal Cortex Hormones; Allopurinol; Amiodarone; Animals; Antimalarials; Antineoplastic Agents; Ant | 1985 |
[Pathologic lens changes in experimental animals following continuous administration of high doses of Desferal].
Topics: Animals; Cataract; Cats; Deferoxamine; Dogs; Edetic Acid; Female; Galactose; Lens, Crystalline; Male | 1967 |
Desferrioxamine in thalassaemia.
Topics: Adolescent; Bone Marrow; Cataract; Child; Child, Preschool; Deferoxamine; Female; Hemoglobinometry; | 1968 |