deferoxamine has been researched along with Cardiotoxicity in 2 studies
Deferoxamine: Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
desferrioxamine B : An acyclic desferrioxamine that is butanedioic acid in which one of the carboxy groups undergoes formal condensation with the primary amino group of N-(5-aminopentyl)-N-hydroxyacetamide and the second carboxy group undergoes formal condensation with the hydroxyamino group of N(1)-(5-aminopentyl)-N(1)-hydroxy-N(4)-[5-(hydroxyamino)pentyl]butanediamide. It is a siderophore native to Streptomyces pilosus biosynthesised by the DesABCD enzyme cluster as a high affinity Fe(III) chelator.
Cardiotoxicity: Damage to the HEART or its function secondary to exposure to toxic substances such as drugs used in CHEMOTHERAPY; IMMUNOTHERAPY; or RADIATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Deferoxamine (DFO) is an iron chelating agent that has recently shown antioxidant and antiapoptotic effects." | 5.56 | Protective effects of deferoxamine on lead-induced cardiotoxicity in rats. ( Aminzadeh, A; Gazeri, A, 2020) |
| "Deferoxamine (DFO) is an iron chelating agent that has recently shown antioxidant and antiapoptotic effects." | 1.56 | Protective effects of deferoxamine on lead-induced cardiotoxicity in rats. ( Aminzadeh, A; Gazeri, A, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gazeri, A | 1 |
| Aminzadeh, A | 1 |
| Elgharabawy, RM | 1 |
| Elgharbawy, DM | 1 |
| Emara, AM | 1 |
2 other studies available for deferoxamine and Cardiotoxicity
| Article | Year |
|---|---|
Protective effects of deferoxamine on lead-induced cardiotoxicity in rats.
Topics: Adult; Animals; Cardiotoxicity; Deferoxamine; Dose-Response Relationship, Drug; Female; Humans; Iron | 2020 |
Activation of the molecular and functional effects of Nrf2 against chronic iron oxide nanorod overload-induced cardiotoxicity.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Cardiotoxicity; Deferiprone; Deferoxamine; Deoxyguanosine; Glu | 2018 |