deferoxamine has been researched along with Cardiomyopathy, Dilated in 6 studies
Deferoxamine: Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
desferrioxamine B : An acyclic desferrioxamine that is butanedioic acid in which one of the carboxy groups undergoes formal condensation with the primary amino group of N-(5-aminopentyl)-N-hydroxyacetamide and the second carboxy group undergoes formal condensation with the hydroxyamino group of N(1)-(5-aminopentyl)-N(1)-hydroxy-N(4)-[5-(hydroxyamino)pentyl]butanediamide. It is a siderophore native to Streptomyces pilosus biosynthesised by the DesABCD enzyme cluster as a high affinity Fe(III) chelator.
Cardiomyopathy, Dilated: A form of CARDIAC MUSCLE disease that is characterized by ventricular dilation, VENTRICULAR DYSFUNCTION, and HEART FAILURE. Risk factors include SMOKING; ALCOHOL DRINKING; HYPERTENSION; INFECTION; PREGNANCY; and mutations in the LMNA gene encoding LAMIN TYPE A, a NUCLEAR LAMINA protein.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Iron overload is one of the major causes of morbidity and death in patients undergoing chronic transfusion therapy." | 2.48 | Iron chelation therapy in the management of transfusion-related cardiac iron overload. ( Fernandes, JL, 2012) |
| "Type 3 hemochromatosis is a rare autosomal recessive disorder due to mutations of the TFR2 gene." | 1.32 | Type 3 hemochromatosis and beta-thalassemia trait. ( Arosio, C; Bovo, G; Mariani, R; Pelucchi, S; Piperno, A; Riva, A; Salvioni, A; Vergani, A, 2004) |
| "Deferoxamine therapy was continued throughout 2 pregnancies, while in the other it was stopped after 8 weeks: no abnormalities were noted in the children." | 1.31 | High-risk pregnancy in beta-thalassemia major women. Report of three cases. ( De Marzi, CA; Magliari, F; Perniola, R; Rosatelli, MC, 2000) |
| "Severe congestive cardiac failure developed in a few weeks in a 44 year old man who had undergone porto-caval anastamosis for post-hepatitis cirrhosis one year previously and then treated for anaemia by repeated blood transfusion and chronic daily oral iron therapy." | 1.27 | [Adiastole caused by a secondary cardiac hemochromatosis. Successful treatment with an iron chelating agent]. ( Azancot, I; Baudouy, P; Lombrail, P; Martin, E; Piekarski, A; Slama, R, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (16.67) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 3 (50.00) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fernandes, JL | 1 |
| Riva, A | 1 |
| Mariani, R | 1 |
| Bovo, G | 1 |
| Pelucchi, S | 1 |
| Arosio, C | 1 |
| Salvioni, A | 1 |
| Vergani, A | 1 |
| Piperno, A | 1 |
| Porcu, M | 1 |
| Landis, N | 1 |
| Salis, S | 1 |
| Corda, M | 1 |
| Orrù, P | 1 |
| Serra, E | 1 |
| Usai, B | 1 |
| Matta, G | 1 |
| Galanello, R | 1 |
| Baudouy, P | 1 |
| Lombrail, P | 1 |
| Azancot, I | 1 |
| Piekarski, A | 1 |
| Martin, E | 1 |
| Slama, R | 1 |
| Politi, A | 1 |
| Sticca, M | 1 |
| Galli, M | 1 |
| Perniola, R | 1 |
| Magliari, F | 1 |
| Rosatelli, MC | 1 |
| De Marzi, CA | 1 |
1 review available for deferoxamine and Cardiomyopathy, Dilated
| Article | Year |
|---|---|
Iron chelation therapy in the management of transfusion-related cardiac iron overload.
Topics: Benzoates; Cardiomyopathy, Dilated; Chelation Therapy; Cross-Sectional Studies; Deferasirox; Deferip | 2012 |
5 other studies available for deferoxamine and Cardiomyopathy, Dilated
| Article | Year |
|---|---|
Type 3 hemochromatosis and beta-thalassemia trait.
Topics: Adult; Amino Acid Substitution; beta-Thalassemia; Biopsy; Cardiomyopathy, Dilated; Chelation Therapy | 2004 |
Effects of combined deferiprone and desferrioxamine iron chelating therapy in beta-thalassemia major end-stage heart failure: a case report.
Topics: Adult; beta-Thalassemia; Cardiomyopathy, Dilated; Deferiprone; Deferoxamine; Drug Therapy, Combinati | 2007 |
[Adiastole caused by a secondary cardiac hemochromatosis. Successful treatment with an iron chelating agent].
Topics: Adult; Arrhythmias, Cardiac; Cardiomyopathy, Dilated; Deferoxamine; Diastole; Echocardiography; Elec | 1983 |
Reversal of haemochromatotic cardiomyopathy in beta thalassaemia by chelation therapy.
Topics: Adult; beta-Thalassemia; Cardiomyopathy, Dilated; Chelation Therapy; Deferoxamine; Female; Hemochrom | 1995 |
High-risk pregnancy in beta-thalassemia major women. Report of three cases.
Topics: Adult; Aspirin; beta-Thalassemia; Cardiomyopathy, Dilated; Deferoxamine; Female; Humans; Pregnancy; | 2000 |