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deferoxamine and Cardiac Death

deferoxamine has been researched along with Cardiac Death in 3 studies

Deferoxamine: Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
desferrioxamine B : An acyclic desferrioxamine that is butanedioic acid in which one of the carboxy groups undergoes formal condensation with the primary amino group of N-(5-aminopentyl)-N-hydroxyacetamide and the second carboxy group undergoes formal condensation with the hydroxyamino group of N(1)-(5-aminopentyl)-N(1)-hydroxy-N(4)-[5-(hydroxyamino)pentyl]butanediamide. It is a siderophore native to Streptomyces pilosus biosynthesised by the DesABCD enzyme cluster as a high affinity Fe(III) chelator.

Research Excerpts

ExcerptRelevanceReference
"Cardiac events and death are not uncommon in adults with beta-thalassemia (b-TM) taking deferoxamine (DFO) monotherapy because of poor compliance and possibly the less effectiveness of DFO in controlling cardiac iron overload."7.76Cardiac events and cardiac T2* in Egyptian children and young adults with beta-thalassemia major taking deferoxamine. ( Abdin, IA; Ebeid, FS; El Safy, UR; Elalfy, MS; Ibrahim, AS; Salem, DS, 2010)
"Cardiac events and death are not uncommon in adults with beta-thalassemia (b-TM) taking deferoxamine (DFO) monotherapy because of poor compliance and possibly the less effectiveness of DFO in controlling cardiac iron overload."3.76Cardiac events and cardiac T2* in Egyptian children and young adults with beta-thalassemia major taking deferoxamine. ( Abdin, IA; Ebeid, FS; El Safy, UR; Elalfy, MS; Ibrahim, AS; Salem, DS, 2010)
"The risk of cardiac death during 1990-1999 and 2000-2008 was compared."1.36Relation of chelation regimes to cardiac mortality and morbidity in patients with thalassaemia major: an observational study from a large Greek Unit. ( Berdoukas, V; Berdoussi, E; Chouliaras, G; Kattamis, C; Ladis, V; Moraitis, P; Zannikos, K, 2010)
"The incidence of cardiac death in both groups was analyzed."1.33Survival in thalassaemia major patients. ( Efthimiadis, GK; Giannakoulas, GA; Hassapopoulou, HP; Karvounis, HI; Louridas, GE; Parharidis, GE; Tsikaderis, DD, 2006)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (33.33)29.6817
2010's2 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ladis, V1
Chouliaras, G1
Berdoukas, V1
Moraitis, P1
Zannikos, K1
Berdoussi, E1
Kattamis, C1
Elalfy, MS1
Abdin, IA1
El Safy, UR1
Ibrahim, AS1
Ebeid, FS1
Salem, DS1
Efthimiadis, GK1
Hassapopoulou, HP1
Tsikaderis, DD1
Karvounis, HI1
Giannakoulas, GA1
Parharidis, GE1
Louridas, GE1

Other Studies

3 other studies available for deferoxamine and Cardiac Death

ArticleYear
Relation of chelation regimes to cardiac mortality and morbidity in patients with thalassaemia major: an observational study from a large Greek Unit.
    European journal of haematology, 2010, Volume: 85, Issue:4

    Topics: Adolescent; Adult; Age Factors; Benzoates; beta-Thalassemia; Child; Death; Deferasirox; Deferiprone;

2010
Cardiac events and cardiac T2* in Egyptian children and young adults with beta-thalassemia major taking deferoxamine.
    Hematology/oncology and stem cell therapy, 2010, Volume: 3, Issue:4

    Topics: Adolescent; Age Factors; Benzoates; beta-Thalassemia; Child; Child, Preschool; Death; Deferasirox; D

2010
Survival in thalassaemia major patients.
    Circulation journal : official journal of the Japanese Circulation Society, 2006, Volume: 70, Issue:8

    Topics: Adolescent; Adult; beta-Thalassemia; Chelation Therapy; Death; Deferoxamine; Echocardiography, Doppl

2006