deferoxamine has been researched along with Carcinoma, Squamous Cell in 14 studies
Deferoxamine: Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
desferrioxamine B : An acyclic desferrioxamine that is butanedioic acid in which one of the carboxy groups undergoes formal condensation with the primary amino group of N-(5-aminopentyl)-N-hydroxyacetamide and the second carboxy group undergoes formal condensation with the hydroxyamino group of N(1)-(5-aminopentyl)-N(1)-hydroxy-N(4)-[5-(hydroxyamino)pentyl]butanediamide. It is a siderophore native to Streptomyces pilosus biosynthesised by the DesABCD enzyme cluster as a high affinity Fe(III) chelator.
Carcinoma, Squamous Cell: A carcinoma derived from stratified SQUAMOUS EPITHELIAL CELLS. It may also occur in sites where glandular or columnar epithelium is normally present. (From Stedman, 25th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Deferoxamine (DFO) was found to modulate multiple cellular pathways involved in the growth of breast cancer, hepatocellular carcinoma, lung cancer and bladder cancer." | 1.48 | Deferoxamine suppresses esophageal squamous cell carcinoma cell growth via ERK1/2 mediated mitochondrial dysfunction. ( Chen, X; Gao, Y; Guo, M; Huang, D; Lan, L; Liu, Y; Lu, B; Lu, J; Mo, S; Niu, L; Wei, W; Zheng, Y, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (21.43) | 18.2507 |
| 2000's | 4 (28.57) | 29.6817 |
| 2010's | 7 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lan, L | 1 |
| Wei, W | 1 |
| Zheng, Y | 1 |
| Niu, L | 1 |
| Chen, X | 1 |
| Huang, D | 2 |
| Gao, Y | 1 |
| Mo, S | 1 |
| Lu, J | 1 |
| Guo, M | 1 |
| Liu, Y | 2 |
| Lu, B | 1 |
| Yamamoto, M | 1 |
| Fujita, H | 1 |
| Katase, N | 1 |
| Inoue, K | 1 |
| Nagatsuka, H | 1 |
| Utsumi, K | 1 |
| Sasaki, J | 1 |
| Ohuchi, H | 1 |
| Patel, K | 1 |
| Wen, J | 1 |
| Magliocca, K | 1 |
| Muller, S | 1 |
| Chen, ZG | 1 |
| Saba, N | 1 |
| Diaz, R | 1 |
| Zhou, X | 1 |
| Xue, Z | 1 |
| Xu, X | 1 |
| Wang, K | 1 |
| Sun, Y | 1 |
| Kang, F | 1 |
| de Souza, AL | 1 |
| Marra, K | 1 |
| Gunn, J | 1 |
| Samkoe, KS | 1 |
| Kanick, SC | 1 |
| Davis, SC | 1 |
| Chapman, MS | 1 |
| Maytin, EV | 1 |
| Hasan, T | 2 |
| Pogue, BW | 1 |
| Perk, LR | 1 |
| Vosjan, MJ | 1 |
| Visser, GW | 1 |
| Budde, M | 1 |
| Jurek, P | 1 |
| Kiefer, GE | 1 |
| van Dongen, GA | 1 |
| Uekusa, M | 1 |
| Omura, K | 1 |
| Nakajima, Y | 1 |
| Hasegawa, S | 1 |
| Harada, H | 1 |
| Morita, KI | 1 |
| Tsuda, H | 1 |
| Gross, J | 1 |
| Fuchs, J | 1 |
| Machulik, A | 1 |
| Jahnke, V | 1 |
| Kietzmann, T | 1 |
| Bockmühl, U | 1 |
| Nakagawa, H | 1 |
| Matsumiya, T | 1 |
| Sakaki, H | 1 |
| Imaizumi, T | 1 |
| Kubota, K | 1 |
| Kusumi, A | 1 |
| Kobayashi, W | 1 |
| Kimura, H | 1 |
| Curnow, A | 1 |
| Pye, A | 1 |
| Lee, SK | 2 |
| Lee, J | 1 |
| Min, SK | 1 |
| Won, DH | 1 |
| Lee, YM | 1 |
| Lim, HD | 1 |
| Lee, W | 1 |
| Pae, HO | 1 |
| Chung, HT | 1 |
| Jun, CD | 1 |
| Kim, EC | 1 |
| Iinuma, S | 1 |
| Farshi, SS | 1 |
| Ortel, B | 2 |
| Tanew, A | 1 |
| Hönigsmann, H | 1 |
| Kitazono, M | 1 |
| Takebayashi, Y | 1 |
| Ishitsuka, K | 1 |
| Takao, S | 1 |
| Tani, A | 1 |
| Furukawa, T | 1 |
| Miyadera, K | 1 |
| Yamada, Y | 1 |
| Aikou, T | 1 |
| Akiyama, S | 1 |
14 other studies available for deferoxamine and Carcinoma, Squamous Cell
| Article | Year |
|---|---|
Deferoxamine suppresses esophageal squamous cell carcinoma cell growth via ERK1/2 mediated mitochondrial dysfunction.
Topics: Animals; Apoptosis; Carcinoma, Squamous Cell; Cell Movement; Cell Proliferation; Deferoxamine; Esoph | 2018 |
Improvement of the efficacy of 5-aminolevulinic acid-mediated photodynamic treatment in human oral squamous cell carcinoma HSC-4.
Topics: Amino Acid Chloromethyl Ketones; Aminolevulinic Acid; Apoptosis; ATP Binding Cassette Transporter, S | 2013 |
Heat shock protein 90 (HSP90) is overexpressed in p16-negative oropharyngeal squamous cell carcinoma, and its inhibition in vitro potentiates the effects of chemoradiation.
Topics: Antineoplastic Agents; Apoptosis; Blotting, Western; Carcinoma, Squamous Cell; Cell Hypoxia; Cell Li | 2014 |
Effect of HIF-1α on biological activation of human tongue squamous cell carcinoma SCC-15 cells in vitro.
Topics: Apoptosis; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Movement; Cell Proliferation; Deferoxami | 2015 |
Comparing desferrioxamine and light fractionation enhancement of ALA-PpIX photodynamic therapy in skin cancer.
Topics: Aminolevulinic Acid; Animals; Carcinoma, Squamous Cell; Cell Line, Tumor; Deferoxamine; Dose Fractio | 2016 |
p-Isothiocyanatobenzyl-desferrioxamine: a new bifunctional chelate for facile radiolabeling of monoclonal antibodies with zirconium-89 for immuno-PET imaging.
Topics: Animals; Antibodies, Monoclonal; Carcinoma, Squamous Cell; Cell Line, Tumor; Chelating Agents; Defer | 2010 |
Uptake and kinetics of 5-aminolevulinic acid in oral squamous cell carcinoma.
Topics: Amino Acids, Neutral; Animals; Carcinoma, Squamous Cell; Cell Differentiation; Deferoxamine; Drug Co | 2010 |
Apoptosis, necrosis and hypoxia inducible factor-1 in human head and neck squamous cell carcinoma cultures.
Topics: Acetylcysteine; Apoptosis; Carcinoma, Squamous Cell; Cell Hypoxia; Cell Line, Tumor; Cell Nucleus; C | 2005 |
Expression of vascular endothelial growth factor by photodynamic therapy with mono-L-aspartyl chlorin e6 (NPe6) in oral squamous cell carcinoma.
Topics: Carcinoma, Squamous Cell; Cell Line, Tumor; Cycloheximide; Deferoxamine; Enzyme Inhibitors; Enzyme-L | 2007 |
Biochemical manipulation via iron chelation to enhance porphyrin production from porphyrin precursors.
Topics: Aminolevulinic Acid; Carcinoma, Squamous Cell; Cell Line, Tumor; Deferoxamine; Dose-Response Relatio | 2007 |
Iron chelator differentially activates macrophage inflammatory protein-3alpha/CCL20 in immortalized and malignant human oral keratinocytes.
Topics: Carcinoma, Squamous Cell; Chemokine CCL20; Deferoxamine; Enzyme-Linked Immunosorbent Assay; Female; | 2008 |
A mechanistic study of cellular photodestruction with 5-aminolaevulinic acid-induced porphyrin.
Topics: Aminolevulinic Acid; Animals; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Cell Division; | 1994 |
Lethal photosensitization by endogenous porphyrins of PAM cells--modification by desferrioxamine.
Topics: Aminolevulinic Acid; Animals; Carcinoma, Squamous Cell; Cell Division; Cell Survival; Darkness; Defe | 1993 |
Prevention of hypoxia-induced apoptosis by the angiogenic factor thymidine phosphorylase.
Topics: Angiogenesis Inducing Agents; Apoptosis; Carcinoma, Squamous Cell; Cell Hypoxia; Cobalt; Deferoxamin | 1998 |