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deferoxamine and Carcinoma, Epidermoid

deferoxamine has been researched along with Carcinoma, Epidermoid in 14 studies

Deferoxamine: Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
desferrioxamine B : An acyclic desferrioxamine that is butanedioic acid in which one of the carboxy groups undergoes formal condensation with the primary amino group of N-(5-aminopentyl)-N-hydroxyacetamide and the second carboxy group undergoes formal condensation with the hydroxyamino group of N(1)-(5-aminopentyl)-N(1)-hydroxy-N(4)-[5-(hydroxyamino)pentyl]butanediamide. It is a siderophore native to Streptomyces pilosus biosynthesised by the DesABCD enzyme cluster as a high affinity Fe(III) chelator.

Research Excerpts

ExcerptRelevanceReference
"Deferoxamine (DFO) was found to modulate multiple cellular pathways involved in the growth of breast cancer, hepatocellular carcinoma, lung cancer and bladder cancer."1.48Deferoxamine suppresses esophageal squamous cell carcinoma cell growth via ERK1/2 mediated mitochondrial dysfunction. ( Chen, X; Gao, Y; Guo, M; Huang, D; Lan, L; Liu, Y; Lu, B; Lu, J; Mo, S; Niu, L; Wei, W; Zheng, Y, 2018)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (21.43)18.2507
2000's4 (28.57)29.6817
2010's7 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lan, L1
Wei, W1
Zheng, Y1
Niu, L1
Chen, X1
Huang, D2
Gao, Y1
Mo, S1
Lu, J1
Guo, M1
Liu, Y2
Lu, B1
Yamamoto, M1
Fujita, H1
Katase, N1
Inoue, K1
Nagatsuka, H1
Utsumi, K1
Sasaki, J1
Ohuchi, H1
Patel, K1
Wen, J1
Magliocca, K1
Muller, S1
Chen, ZG1
Saba, N1
Diaz, R1
Zhou, X1
Xue, Z1
Xu, X1
Wang, K1
Sun, Y1
Kang, F1
de Souza, AL1
Marra, K1
Gunn, J1
Samkoe, KS1
Kanick, SC1
Davis, SC1
Chapman, MS1
Maytin, EV1
Hasan, T2
Pogue, BW1
Perk, LR1
Vosjan, MJ1
Visser, GW1
Budde, M1
Jurek, P1
Kiefer, GE1
van Dongen, GA1
Uekusa, M1
Omura, K1
Nakajima, Y1
Hasegawa, S1
Harada, H1
Morita, KI1
Tsuda, H1
Gross, J1
Fuchs, J1
Machulik, A1
Jahnke, V1
Kietzmann, T1
Bockmühl, U1
Nakagawa, H1
Matsumiya, T1
Sakaki, H1
Imaizumi, T1
Kubota, K1
Kusumi, A1
Kobayashi, W1
Kimura, H1
Curnow, A1
Pye, A1
Lee, SK2
Lee, J1
Min, SK1
Won, DH1
Lee, YM1
Lim, HD1
Lee, W1
Pae, HO1
Chung, HT1
Jun, CD1
Kim, EC1
Iinuma, S1
Farshi, SS1
Ortel, B2
Tanew, A1
Hönigsmann, H1
Kitazono, M1
Takebayashi, Y1
Ishitsuka, K1
Takao, S1
Tani, A1
Furukawa, T1
Miyadera, K1
Yamada, Y1
Aikou, T1
Akiyama, S1

Other Studies

14 other studies available for deferoxamine and Carcinoma, Epidermoid

ArticleYear
Deferoxamine suppresses esophageal squamous cell carcinoma cell growth via ERK1/2 mediated mitochondrial dysfunction.
    Cancer letters, 2018, 09-28, Volume: 432

    Topics: Animals; Apoptosis; Carcinoma, Squamous Cell; Cell Movement; Cell Proliferation; Deferoxamine; Esoph

2018
Improvement of the efficacy of 5-aminolevulinic acid-mediated photodynamic treatment in human oral squamous cell carcinoma HSC-4.
    Acta medica Okayama, 2013, Volume: 67, Issue:3

    Topics: Amino Acid Chloromethyl Ketones; Aminolevulinic Acid; Apoptosis; ATP Binding Cassette Transporter, S

2013
Heat shock protein 90 (HSP90) is overexpressed in p16-negative oropharyngeal squamous cell carcinoma, and its inhibition in vitro potentiates the effects of chemoradiation.
    Cancer chemotherapy and pharmacology, 2014, Volume: 74, Issue:5

    Topics: Antineoplastic Agents; Apoptosis; Blotting, Western; Carcinoma, Squamous Cell; Cell Hypoxia; Cell Li

2014
Effect of HIF-1α on biological activation of human tongue squamous cell carcinoma SCC-15 cells in vitro.
    International journal of oncology, 2015, Volume: 46, Issue:6

    Topics: Apoptosis; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Movement; Cell Proliferation; Deferoxami

2015
Comparing desferrioxamine and light fractionation enhancement of ALA-PpIX photodynamic therapy in skin cancer.
    British journal of cancer, 2016, 09-27, Volume: 115, Issue:7

    Topics: Aminolevulinic Acid; Animals; Carcinoma, Squamous Cell; Cell Line, Tumor; Deferoxamine; Dose Fractio

2016
p-Isothiocyanatobenzyl-desferrioxamine: a new bifunctional chelate for facile radiolabeling of monoclonal antibodies with zirconium-89 for immuno-PET imaging.
    European journal of nuclear medicine and molecular imaging, 2010, Volume: 37, Issue:2

    Topics: Animals; Antibodies, Monoclonal; Carcinoma, Squamous Cell; Cell Line, Tumor; Chelating Agents; Defer

2010
Uptake and kinetics of 5-aminolevulinic acid in oral squamous cell carcinoma.
    International journal of oral and maxillofacial surgery, 2010, Volume: 39, Issue:8

    Topics: Amino Acids, Neutral; Animals; Carcinoma, Squamous Cell; Cell Differentiation; Deferoxamine; Drug Co

2010
Apoptosis, necrosis and hypoxia inducible factor-1 in human head and neck squamous cell carcinoma cultures.
    International journal of oncology, 2005, Volume: 27, Issue:3

    Topics: Acetylcysteine; Apoptosis; Carcinoma, Squamous Cell; Cell Hypoxia; Cell Line, Tumor; Cell Nucleus; C

2005
Expression of vascular endothelial growth factor by photodynamic therapy with mono-L-aspartyl chlorin e6 (NPe6) in oral squamous cell carcinoma.
    Oral oncology, 2007, Volume: 43, Issue:6

    Topics: Carcinoma, Squamous Cell; Cell Line, Tumor; Cycloheximide; Deferoxamine; Enzyme Inhibitors; Enzyme-L

2007
Biochemical manipulation via iron chelation to enhance porphyrin production from porphyrin precursors.
    Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer, 2007, Volume: 26, Issue:2

    Topics: Aminolevulinic Acid; Carcinoma, Squamous Cell; Cell Line, Tumor; Deferoxamine; Dose-Response Relatio

2007
Iron chelator differentially activates macrophage inflammatory protein-3alpha/CCL20 in immortalized and malignant human oral keratinocytes.
    Archives of oral biology, 2008, Volume: 53, Issue:9

    Topics: Carcinoma, Squamous Cell; Chemokine CCL20; Deferoxamine; Enzyme-Linked Immunosorbent Assay; Female;

2008
A mechanistic study of cellular photodestruction with 5-aminolaevulinic acid-induced porphyrin.
    British journal of cancer, 1994, Volume: 70, Issue:1

    Topics: Aminolevulinic Acid; Animals; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Cell Division;

1994
Lethal photosensitization by endogenous porphyrins of PAM cells--modification by desferrioxamine.
    Journal of photochemistry and photobiology. B, Biology, 1993, Volume: 17, Issue:3

    Topics: Aminolevulinic Acid; Animals; Carcinoma, Squamous Cell; Cell Division; Cell Survival; Darkness; Defe

1993
Prevention of hypoxia-induced apoptosis by the angiogenic factor thymidine phosphorylase.
    Biochemical and biophysical research communications, 1998, Dec-30, Volume: 253, Issue:3

    Topics: Angiogenesis Inducing Agents; Apoptosis; Carcinoma, Squamous Cell; Cell Hypoxia; Cobalt; Deferoxamin

1998