deferoxamine has been researched along with Carcinogenesis in 3 studies
Deferoxamine: Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
desferrioxamine B : An acyclic desferrioxamine that is butanedioic acid in which one of the carboxy groups undergoes formal condensation with the primary amino group of N-(5-aminopentyl)-N-hydroxyacetamide and the second carboxy group undergoes formal condensation with the hydroxyamino group of N(1)-(5-aminopentyl)-N(1)-hydroxy-N(4)-[5-(hydroxyamino)pentyl]butanediamide. It is a siderophore native to Streptomyces pilosus biosynthesised by the DesABCD enzyme cluster as a high affinity Fe(III) chelator.
Carcinogenesis: The origin, production or development of cancer through genotypic and phenotypic changes which upset the normal balance between cell proliferation and cell death. Carcinogenesis generally requires a constellation of steps, which may occur quickly or over a period of many years.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Asbestos-induced mesothelial carcinogenesis is currently a profound social issue due to its extremely long incubation period and high mortality rate." | 1.43 | Dual preventive benefits of iron elimination by desferal in asbestos-induced mesothelial carcinogenesis. ( Akatsuka, S; Chew, SH; Jiang, L; Nakamura, K; Ohara, Y; Toyokuni, S, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Sandoval-Acuña, C | 1 |
| Torrealba, N | 1 |
| Tomkova, V | 1 |
| Jadhav, SB | 1 |
| Blazkova, K | 1 |
| Merta, L | 1 |
| Lettlova, S | 1 |
| Adamcová, MK | 1 |
| Rosel, D | 1 |
| Brábek, J | 1 |
| Neuzil, J | 1 |
| Stursa, J | 1 |
| Werner, L | 1 |
| Truksa, J | 1 |
| Kuang, Y | 1 |
| Guo, W | 1 |
| Ling, J | 1 |
| Xu, D | 1 |
| Liao, Y | 1 |
| Zhao, H | 1 |
| Du, X | 1 |
| Wang, H | 1 |
| Xu, M | 1 |
| Song, H | 1 |
| Wang, T | 1 |
| Jing, B | 1 |
| Li, K | 1 |
| Hu, M | 1 |
| Wu, W | 1 |
| Deng, J | 1 |
| Wang, Q | 1 |
| Jiang, L | 1 |
| Chew, SH | 1 |
| Nakamura, K | 1 |
| Ohara, Y | 1 |
| Akatsuka, S | 1 |
| Toyokuni, S | 1 |
3 other studies available for deferoxamine and Carcinogenesis
| Article | Year |
|---|---|
Targeting Mitochondrial Iron Metabolism Suppresses Tumor Growth and Metastasis by Inducing Mitochondrial Dysfunction and Mitophagy.
Topics: Animals; Carcinogenesis; Cell Death; Cell Movement; Cell Proliferation; Deferoxamine; Heme; Humans; | 2021 |
Iron-dependent CDK1 activity promotes lung carcinogenesis via activation of the GP130/STAT3 signaling pathway.
Topics: A549 Cells; Adaptor Proteins, Signal Transducing; Adenocarcinoma of Lung; Animals; Carcinogenesis; C | 2019 |
Dual preventive benefits of iron elimination by desferal in asbestos-induced mesothelial carcinogenesis.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Asbestos; Body Weight; Carcinogenesis; Cell Proliferation; Def | 2016 |