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deferoxamine and Canine Diseases

deferoxamine has been researched along with Canine Diseases in 4 studies

Deferoxamine: Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
desferrioxamine B : An acyclic desferrioxamine that is butanedioic acid in which one of the carboxy groups undergoes formal condensation with the primary amino group of N-(5-aminopentyl)-N-hydroxyacetamide and the second carboxy group undergoes formal condensation with the hydroxyamino group of N(1)-(5-aminopentyl)-N(1)-hydroxy-N(4)-[5-(hydroxyamino)pentyl]butanediamide. It is a siderophore native to Streptomyces pilosus biosynthesised by the DesABCD enzyme cluster as a high affinity Fe(III) chelator.

Research Excerpts

ExcerptRelevanceReference
"The iron-chelating agent deferoxamine (DF) was administered as a single dose and also daily over a prolonged period to evaluate availability of storage iron in dogs with induced anemia of inflammatory disease."3.66Anemia of inflammatory disease in the dog: availability of storage iron in inflammatory disease. ( Farver, TB; Feldman, BF; Kaneko, JJ, 1981)
" Chelation therapy with desferrioxamine mesylate did not cause adverse effects in any of the dogs and all survived to discharge."1.35Acute toxicity in five dogs after ingestion of a commercial snail and slug bait containing iron EDTA. ( Davis, RM; Haldane, SL, 2009)
"In dogs, gastric dilatation-volvulus (GDV) is characterized by cardiogenic shock, with resulting hypoperfusion."1.28Treatment of reperfusion injury in dogs with experimentally induced gastric dilatation-volvulus. ( Arkin, TE; Badylak, SF; Hiles, MC; Lantz, GC, 1992)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19901 (25.00)18.7374
1990's1 (25.00)18.2507
2000's1 (25.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Alves, RN1
Levenhagen, MA1
Levenhagen, MM1
Rieck, SE1
Labruna, MB1
Beletti, ME1
Haldane, SL1
Davis, RM1
Feldman, BF1
Kaneko, JJ1
Farver, TB1
Lantz, GC1
Badylak, SF1
Hiles, MC1
Arkin, TE1

Other Studies

4 other studies available for deferoxamine and Canine Diseases

ArticleYear
The spreading process of Ehrlichia canis in macrophages is dependent on actin cytoskeleton, calcium and iron influx and lysosomal evasion.
    Veterinary microbiology, 2014, Jan-31, Volume: 168, Issue:2-4

    Topics: Actin Cytoskeleton; Animals; Calcium; Calcium Channel Blockers; Cells, Cultured; Cytochalasins; Defe

2014
Acute toxicity in five dogs after ingestion of a commercial snail and slug bait containing iron EDTA.
    Australian veterinary journal, 2009, Volume: 87, Issue:7

    Topics: Animals; Deferoxamine; Dog Diseases; Dogs; Female; Gastrointestinal Diseases; Iron; Male; Siderophor

2009
Anemia of inflammatory disease in the dog: availability of storage iron in inflammatory disease.
    American journal of veterinary research, 1981, Volume: 42, Issue:4

    Topics: Anemia; Animals; Biological Availability; Deferoxamine; Dog Diseases; Dogs; Female; Ferritins; Hemos

1981
Treatment of reperfusion injury in dogs with experimentally induced gastric dilatation-volvulus.
    American journal of veterinary research, 1992, Volume: 53, Issue:9

    Topics: Animals; Deferoxamine; Dimethyl Sulfoxide; Disease Models, Animal; Dog Diseases; Dogs; Gastric Dilat

1992