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deferoxamine and Candida Infection

deferoxamine has been researched along with Candida Infection in 2 studies

Deferoxamine: Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
desferrioxamine B : An acyclic desferrioxamine that is butanedioic acid in which one of the carboxy groups undergoes formal condensation with the primary amino group of N-(5-aminopentyl)-N-hydroxyacetamide and the second carboxy group undergoes formal condensation with the hydroxyamino group of N(1)-(5-aminopentyl)-N(1)-hydroxy-N(4)-[5-(hydroxyamino)pentyl]butanediamide. It is a siderophore native to Streptomyces pilosus biosynthesised by the DesABCD enzyme cluster as a high affinity Fe(III) chelator.

Research Excerpts

ExcerptRelevanceReference
"This study investigates the pathophysiology of mucormycosis caused by Rhizopus, which has been reported in 46 dialysis patients, while treated with deferoxamine (DFO)."7.68Mucormycosis during deferoxamine therapy is a siderophore-mediated infection. In vitro and in vivo animal studies. ( Boelaert, JR; Cantinieaux, B; de Locht, M; Kerrels, V; Schneider, YJ; Van Cutsem, J; Van Landuyt, HW; Verdonck, A, 1993)
"This study investigates the pathophysiology of mucormycosis caused by Rhizopus, which has been reported in 46 dialysis patients, while treated with deferoxamine (DFO)."3.68Mucormycosis during deferoxamine therapy is a siderophore-mediated infection. In vitro and in vivo animal studies. ( Boelaert, JR; Cantinieaux, B; de Locht, M; Kerrels, V; Schneider, YJ; Van Cutsem, J; Van Landuyt, HW; Verdonck, A, 1993)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Boelaert, JR2
de Locht, M1
Van Cutsem, J1
Kerrels, V1
Cantinieaux, B1
Verdonck, A1
Van Landuyt, HW1
Schneider, YJ1
Mencacci, A1
Cenci, E1
Bucci, P1
Mosci, P1
Fè d'Ostiani, C1
Bistoni, F1
Romani, L1

Other Studies

2 other studies available for deferoxamine and Candida Infection

ArticleYear
Mucormycosis during deferoxamine therapy is a siderophore-mediated infection. In vitro and in vivo animal studies.
    The Journal of clinical investigation, 1993, Volume: 91, Issue:5

    Topics: Animals; Blood Physiological Phenomena; Candida albicans; Candidiasis; Deferoxamine; Guinea Pigs; Hu

1993
Iron overload alters innate and T helper cell responses to Candida albicans in mice.
    The Journal of infectious diseases, 1997, Volume: 175, Issue:6

    Topics: Animals; Candida albicans; Candidiasis; Cytokines; Deferoxamine; Disease Susceptibility; Ferric Comp

1997